Authors

    Language

    English

    Publication Date

    1-1-2021

    Journal

    AACE Clinical Case Reports

    DOI

    10.1016/j.aace.2021.06.011

    PMID

    34250225

    PMCID

    PMC8253658

    PubMedCentral® Posted Date

    7-3-2021

    PubMedCentral® Full Text Version

    Post-print

    Abstract

    OBJECTIVE: A thyroid storm is a severe exacerbation of thyrotoxicosis that can cause significant morbidity and mortality. The emergence of the novel coronavirus (SARS-CoV-2) that originated in Wuhan, China, has become a worldwide pandemic. We present the first documented case of thyroid storm (as defined by the Burch-Wartofsky criteria) in a patient with COVID-19.

    METHODS: Laboratory and diagnostic studies, including thyroid function tests, thyroid antibody testing, SARS-CoV-2 nasopharyngeal polymerase chain reaction testing, and thyroid ultrasound were performed.

    RESULTS: A 25-year-old woman presented to the hospital with dry cough, dyspnea, palpitations, weight loss, diarrhea, and anxiety. Physical examination revealed exophthalmos with proptosis and chemosis, tachycardia, diffusely enlarged goiter with bruit, and fine tremor. Laboratory results demonstrated a thyroid-stimulating hormone level of

    CONCLUSION: Thyroid storms are one of the more prevalent endocrine emergencies and are often precipitated by acute events including infections. Patients with thyroid storms may have concomitant SARS-CoV-2 infection that could influence the clinical course and severity of the disease. In patients with symptoms of thyrotoxicosis and respiratory symptoms, clinicians should consider performing a COVID-19 test.

    Keywords

    COVID-19, SARS-CoV-2, thyroid, thyroid storm, NR, normal range; T3, triiodothyronine; T4, thyroxine

    Published Open-Access

    yes

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