Language
English
Publication Date
7-1-2025
Journal
Radiology
DOI
10.1148/radiol.242897
PMID
40728402
PMCID
PMC12314773
PubMedCentral® Posted Date
7-29-2025
PubMedCentral® Full Text Version
Post-print
Abstract
Background Evaluating peripheral nerve response after injury or repair remains a critical clinical challenge. Current medical imaging approaches provide limited insight into the degenerative or regenerative environment of affected nerves. Purpose To assess the efficacy of ultrashort echo time (UTE) quantitative MRI (qMRI) for evaluating peripheral nerve degeneration and regeneration in rat models of sciatic nerve injury and to assess correlations between UTE qMRI parameters and histologic findings. Materials and Methods In this animal study conducted from November 2022 to December 2023, four experimental groups were created in 6-8-week-old male Lewis rats:
Keywords
Animals, Magnetic Resonance Imaging, Rats, Inbred Lew, Rats, Male, Nerve Regeneration, Sciatic Nerve, Disease Models, Animal, Peripheral Nerve Injuries, Nerve Degeneration
Published Open-Access
yes
Recommended Citation
Wu, Yuanshan; Ma, Yajun; Cheng, Xin; et al., "Quantitative Ultrashort Echo Time MRI for Evaluation of Sciatic Nerve Degeneration and Regeneration in Rat Models" (2025). Faculty, Staff and Students Publications. 7988.
https://digitalcommons.library.tmc.edu/baylor_docs/7988