Open-access, full-text copies of UT GSBS dissertations from 2009 onwards. Topics include all aspects of the biomedical sciences.

Older UT GSBS dissertations (from approximately 1979-1999) are available in print format only, in The TMC Library. They are listed in the Catalog. Search by subject heading: "Dissertations, Academic--University of Texas Health Science Center at Houston. Graduate School of Biomedical Sciences" for the full list.

Some older GSBS dissertations are available online via ProQuest, but full-text access is restricted to TMC academic institutions affiliated with The TMC Library.

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Theses/Dissertations from 2017

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ANALYSIS OF THE BIOCHEMICAL AND CELLULAR ACTIVITIES OF SUBSTRATE BINDING BY THE MOLECULAR CHAPERONE HSP110/SSE1, Veronica M. Garcia

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ANDROGEN RECEPTOR AND PROSTATE CANCER CELL HETEROGENEITY, Qu Deng

A PRECLINICAL STUDY OF RADIATION-INDUCED LUNG TOXICITY WHEN IRRADIATING IN A STRONG MAGNETIC FIELD, Ashley E. Rubinstein

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A tail-based test for differential expression analysis and pathway analysis in RNA-sequencing data, Jiong Chen

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Attitudes of Clinicians Towards Cardiac Surgery and Trisomy 18, Meagan Kaulfus

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Attitudes Toward and Uptake of Prenatal Genetic Screening and Testing in Twin Pregnancies, Kathryn M. Reese

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Barriers to Expansion of Supervision Networks at Genetic Counseling Training Programs, Jordan E. Berg

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CD47+ Exosomes Facilitate Effective Targeting of Oncogenic Kras in Pancreatic Cancer, Sushrut Kamerkar

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CHARACTERIZATION AND REVERSAL OF DOXORUBICIN-MEDIATED CHANGES IN SENSORY NEURONS, Brittany L. Coughlin

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CHARACTERIZATION OF THE ROLE OF THE pKM101-ENCODED T4SS OUTER MEMBRANE CORE COMPLEX IN SUBSTRATE TRANSFER, PILUS BIOGENESIS, AND RECIPIENT CELL CONTACT, Jay E. Gordon

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CHARACTERIZATION OF THE UBIQUITIN LIGASE, UBE4B, IN ENDOCYTIC TRAFFICKING, Natalie Sirisaengtaksin and Natalie Sirisaengtaksin

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Characterizing the source of neutrophil elastase and proteinase 3 cross-presentation in B-cell acute lymphoblastic leukemia, Selena Carmona

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CLINICAL AND THERAPEUTIC SIGNIFICANCE OF OBESITY IN MELANOMA, Jennifer L. McQuade

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CLINICAL APPLICABILITY OF PROPOSED ALGORITHM FOR IDENTIFYING INDIVIDUALS AT RISK FOR HEREDITARY HEMATOLOGIC MALIGNANCIES, Maggie Clifford

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Computer-Aided Detection of Pathologically Enlarged Lymph Nodes On Non-Contrast CT In Cervical Cancer Patients For Low-Resource Settings, Brian M. Anderson, Laurence E. Court, Ann Klopp, Stephen F. Kry, Jennifer Johnson, Erik Cressman, Arvind Rao, and Jinzhong Yang

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CONTRASTING EFFECTS OF AN MDM2 FUNCTIONAL POLYMORPHISM ON TUMOR PHENOTYPES, Guadalupe J. Ortiz IV

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Cyclin B1 mediates the effect of UCHL1 in promoting cell cycle progression in uterine papillary serous carcinoma, Suet Ying Kwan

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Detecting and Evaluating Therapy Induced Changes in Radiomics Features Measured from Non-Small Cell Lung Cancer to Predict Patient Outcomes, Xenia J. Fave

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DEVELOPING NOVEL APPROACHES TO IMPROVE RESPONSE TO T CELL BASED CANCER IMMUNOTHERAPY, Rina M. Mbofung

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EFFECT OF ENTINOSTAT ON NK CELL-MEDIATED CYTOTOXICITY AGAINST OS CELLS AND OS LUNG METASTSIS, Simin Kiany

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Evaluating the impact of post-translational modifications by the secreted zinc metalloprotease, GelE, on the major autolysin of E. faecalis, AtlA, and a stress-induced protein, SalB, Emily K. Stinemetz

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FRET-Based Investigations of the Structure-Function Relationships in the NMDA Receptor, Drew M. Dolino

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FUNCTIONAL ASYMMETRY OF THE IMMUNE CELL PLASMA MEMBRANE, Eric Malmberg

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Functional consequences of RNA exosome complex alteration by conformational changes and cofactor binding, Jaeil Han

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FURTHER ADVANCES FOR THE SEQUENTIAL MULTIPLE ASSIGNMENT RANDOMIZED TRIAL (SMART), TIANJIAO DAI

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Gcn5 Impacts FGF Signaling At Multiple Levels And Activates C-Myc Target Genes During Early Differentiation Of Embryoid Bodies, Li Wang

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Genesurance Counseling: Patient Perspectives, Chelsea Wagner

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GSK3B regulates epithelial-mesenchymal transition and cancer stem cell properties and is a novel drug target for triple-negative breast cancer, Geraldine Vidhya Raja

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HIGH-THROUGHPUT MAPPING OF THE BIOLOGICAL EFFECTS OF PARTICLE THERAPY, Lawrence Bronk

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HSP27 AND CHEMOTHERAPY-INDUCED AUTOPHAGY AS BIOMARKERS IN OSTEOSARCOMA, John Andrew Livingston

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IDENTIFYING THE IMMUNE RELATED METABOLIC PROPERTIES OF PANCREATIC CANCER USING NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND DYNAMIC MAGNETIC RESONANCE SPECTROSCOPIC IMAGING WITH HYPERPOLARIZED PYRUVATE, Joseph Weygand

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Image Registration to Map Endoscopic Video to Computed Tomography for Head and Neck Radiotherapy Patients, William S. Ingram

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Improvements in four-dimensional and dual energy computed tomography, Rachael M. Martin

Improvements in Robustness and Optimality of Intensity-Modulated Proton Therapy Plans for Lung Cancer Patients with 4-Dimensional Robust Optimization, shuaiping ge

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IMPROVING NK CELL THERAPY FOR OSTEOSARCOMA, Jennifer Foltz

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INTEGRATIVE ANALYSIS OF OMICS DATA IN ADULT GLIOMA AND OTHER TCGA CANCERS TO GUIDE PRECISION MEDICINE, Xin hu and xin hu

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Investigating the Neural Basis of Audiovisual Speech Perception with Intracranial Recordings in Humans, Muge O. Sertel

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INVESTIGATING THE ROLE OF PRMT1 AND ARGININE METHYLATION OF HSP70 IN HUMAN PANCREATIC CANCER, Liang Wang

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INVESTIGATION OF THE ROLES OF ASF1 AND CAF-1-MEDIATED CHROMATIN ASSEMBLY IN THE HUMAN DNA DAMAGE RESPONSE, Ting-Hsiang Huang

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INVOLVEMENT OF THE RECEPTOR FOR ADVANCED GLYCATION END PRODUCTS (RAGE) IN PROGRESSION OF PANCREATIC CANCER, Nancy Azizian MS

LBPI: A WEB INTERFACE FOR THE IDENTIFICATION OF ALLOSTERIC LIGAND BINDING SITES, Nabina Paudyal

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MANAGING VARIANT DISCREPANCY IN HEREDITARY CANCER: CLINICAL PRACTICE, BARRIERS, AND DESIRED RESOURCES, Ellen Zirkelbach

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MATHEMATICAL MODELING REVEALS THAT G2/M CHECKPOINT OVERRIDE, Hui Ju Hsieh

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MECHANISMS UNDERLYING THE SENSITIVITY AND RESISTANCE OF GASTRIC CANCER CELLS TO MET INHIBITORS, Rebecca Schroeder

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MODIFICATION OF APLYSIA FEEDING NETWORK BY L-DOPA AND DOPAMINE-DEPENDENT LEARNING, Curtis Neveu and Curtis L. Neveu

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MOLECULAR DETERMINANTS OF RESIDUAL DISEASE IN OVARIAN CANCER, Kshipra M. Gharpure

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MOLECULAR MECHANISMS OF INWARD AND OUTWARD BUDDING FROM MULTIVESICULAR ENDOSOMES, Monica Gireud Goss

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NON-CODING RNAS IDENTIFY THE INTRINSIC MOLECULAR SUBTYPES OF MUSCLE-INVASIVE BLADDER CANCER, Andrea E. Ochoa

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NOVEL BAYESIAN ADAPTIVE CLINICAL TRIAL DESIGNS IN EARLY PHASES, Haitao Pan

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On the Origin of Sensory Errors, Jonathan R. Flynn

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Optogenetic interrogation of primary visual cortex and its impact on neural coding and behavior, Ariana R. Andrei

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PARP inhibitor upregulates PD-L1 expression and enhances cancer-associated immunosuppression, Shiping Jiao

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PEPTIDE VACCINE FORMULATION CONTROLS THE DURATION OF ANTIGEN PRESENTATION AND MAGNITUDE OF TUMOR‐SPECIFIC CD8+ T CELL RESPONSE, Hiep Khong

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Pharmacologic and Genetic Manipulations of Angiotensin Signaling in Thoracic Aortic Disease Models, Andrew M. Peters

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PHOPSPHORYLATION AND UBIQUITIN MODIFICATION AT DNA DAMAGE SITES IN RESPONSE TO DOUBLE-STRAND BREAKS, Atanu Paul

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Preclinical Development of Therapeutic Strategies Against Triple-Negative and Inflammatory Breast Cancer, Angie M. Torres-Adorno

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PROTEOMIC IDENTIFICATION OF HISTONE POST-TRANSLATIONAL MODIFICATIONS INDUCED BY DNA DOUBLE-STRAND BREAKS AND NOVEL PROTEINS INVOLVED IN THE DNA DAMAGE RESPONSE, Pingping Wang

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Quantitative DWI as an Early Imaging Biomarker of the Response to Chemoradiation in Esophageal Cancer, Benjamin C. Musall

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ROLE AND REGULATION OF SPHINGOSINE 1-PHOSPHATE IN ERYTHROCYTE, Kaiqi Sun

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STATISTICAL METHODS FOR ASSESSING STRUCTURAL CHANGE IN HUMAN & MICROBIAL GENOMES, Xuan Zhu

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Statistical Methods for Two Problems in Cancer Research: Analysis of RNA-seq Data from Archival Samples and Characterization of Onset of Multiple Primary Cancers, Jialu Li

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Stromal Fibroblasts Restrain the Rate of Colon Cancer Progression and Metastasis by Suppressing Regulatory T Cells and Colon Cancer Stem Cells, Changsoo Kwak

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STRUCTURAL AND FUNCTIONAL EFFECT OF PHOSPHORYLATION ON AMPA RECEPTORS, Caitlin E. Nurik

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TARGETING APOPTOTIC PATHWAYS TO OVERCOME DRUG RESISTANCE IN ACUTE MYELOID LEUKEMIA, Rongqing Pan

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TARGETING AUTOPHAGY TO IMPROVE EFFICACY OF CDK4/6 INHIBITION IN BREAST CANCER, Smruthi Vijayaraghavan

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Targeting Epigenetic Regulators for the Treatment of Diffuse Large B-Cell Lymphoma, Aarthi Goverdhan

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The External Globus Pallidus: Bidirectional Control Over Anxiety-Related Behavior Mediated by CRFR1, Albert J. Hunt Jr

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The Hypoxic Adenosine Response Modulates Macrophage Differentiation and Contributes to Lung Disease, Kemly Mary Philip

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THE ROLE OF ADENOSINE SIGNALING IN MATURE ERYTHROCYTES AND ERYTHROID PROGENITORS, Hong Liu

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The Role of the DIRAS Family Members in Regulating Ras Function, Cancer Growth and Autophagy, Margie Nicole Sutton

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THE ROLE OF THE EPITHELIAL-TO-MESENCHYMAL TRANSITION (EMT) IN LUNG CANCER PROGRESSION, David H. Peng

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The Utilization of Prenatal Microarray: A Survey of Current Genetic Counseling Practices and Barriers, Leslie N. Durham and Leslie Durham

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TUMOR-CELL DERIVED INHIBIN, BETA A IS ESSENTIAL FOR ADRENERGIC EFFECTS ON FIBROBLAST ACTIVATION, Archana Sidalaghatta Nagaraja

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Undergraduate Student Perceptions and Awareness of Genetic Counseling, Amanda Gerard

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UNDERSTANDING THE MECHANISM OF GENOMIC INSTABILITY DURING REPLICATIVE AGING IN BUDDING YEAST, Sangita Pal

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VISUALIZING THE DYNAMICS OF IMMUNE SURVEILLANCE IN BRAIN TUMORS BY INTRAVITAL MULTIPHOTON MICROSCOPY, Felix Nwajei

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VOLUMETRIC, MAGNETIC RESONANCE-VISIBLE, AND RADIATION-SENSITIVE DETECTORS FOR MAGNETIC RESONANCE IMAGE-GUIDED RADIATION THERAPY, Hannah J. Lee

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WISP1 IS AN OVEREXPRESSED DRIVER OF GLIOBLASTOMA, Pushan R. Dasgupta

Theses/Dissertations from 2016

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Accurate mutation annotation and functional prediction enhance the applicability of -omics data in precision medicine, Tenghui Chen

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AN AUTOMATED SYRINGE PUMP SYSTEM FOR IMPROVING THE REPRODUCIBILITY OF DYNAMIC HYPERPOLARIZED MRI PHANTOMS, Harlee G. Harrison

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A Phase I dose-escalation study of the BRAF inhibitor vemurafenib in combination with the MTOR inhibitor everolimus in subjects with advanced cancer, Javier Munoz

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Assessing the Potential Clinical Impact of Variable Biological Effectiveness in Proton Radiotherapy, Christopher R. Peeler Ph.D.

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Attitudes Towards Prenatal Genetics Among Southeast and East Asian Women: A Qualitative Pilot Study, GINGER J. TSAI

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BIAS AND VARIABILITY IN IMAGE-BASED VOLUMETRIC YTTRIUM-90 DOSIMETRY, Wendy Siman

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Cellular and genetic bases of cold nociception and nociceptive sensitization in Drosophila larvae, Heather N. Turner

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Characterization of Stem Cell Turnover in a Living Epithelial Bilayer, Elizabeth Sumner

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Characterization of the ATO Gene Family in Alternative Carbon Metabolism, Heather A. Danhof

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Characterization of Vesicular Monoamine Transporter 2 and its role in Parkinson's Disease Pathogenesis using Drosophila, Antonio Joel Tito Jr. and Sheng Zhang

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CIRCUMVENTING CISPLATIN RESISTANCE IN OVARIAN CANCERS THROUGH REACTIVATION OF p53 BY NON-CROSS-RESISTANT PLATINUM ANALOGS, Michelle Martinez-Rivera

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Clinical Significance of Homologous Recombination Deficiency Score Testing in Endometrial Cancer, Jean M. Hansen

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CLL METABOLISM IS REGULATED BY PROGNOSTIC FACTORS, MODULATED BY STROMA AND ABROGATED BY PI3K INHIBITION, Hima Vangapandu

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CONCOMITANT TARGETING OF THE MTOR/MAPK PATHWAYS: NOVEL THERAPEUTIC STRATEGY IN SUBSETS OF NON-SMALL CELL LUNG CANCER, Dennis Ruder

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¬¬DEFINE THE EPIGENETIC PROFILES AND SUBTYPE-SPECIFIC GENES OF BREAST CANCER, Wenqian Li

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DEFINING THE FUNCTIONS OF USP22 AND USP44 IN REGULATION OF H2BUB1 LEVELS, xianjiang Lan

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Determination of Thermal Dose Model Parameters Using Magnetic Resonance Imaging, Christopher James MacLellan

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Determining Mechanisms of Response to Polo-like Kinase 1 Inhibition in Non-Small Cell Lung Cancer, Ruchitha Goonatilake

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Developing and using methyl-specific antibodies to study the biological roles of arginine methylation, Vidyasiri Vemulapalli

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Development and Implementation of an Anthropomorphic Head & Neck Phantom for the Assessment of Proton Therapy Treatment Procedures, Daniela Branco

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Development Of An In Silico Kir Genotyping Algorithm And Its Application To Population And Cancer Immunogenetic Analyses, Howard Rosoff

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DEVELOPMENT OF RATIONAL COMBINATION THERAPY WITH PARP INHIBITORS AND KINASE INHIBITORS IN TNBC, Wen-Hsuan Yu