Open Access full-text copies of the UT GSBS dissertations from 2009 onwards. Topics include all aspects of the biomedical sciences.

Older UT GSBS dissertations (approximately 1979-1999) are available in print-format only and are available in the HAM-TMC Library. They're listed in the Library Catalog under the subject heading: "Dissertations, Academic--University of Texas Health Science Center at Houston. Graduate School of Biomedical Sciences."

Some older full-text dissertations are also available via ProQuest but access to this database is restricted to the TMC community.

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Theses/Dissertations from 2014

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MECHANISMS UNDERLYING DISTINCT EGFR VERSUS FGFR-3 AND -1 DEPENDENCY IN HUMAN BLADDER CANCER CELLS, Tiewei Cheng

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SYSTEMATIC METHODOLOGY FOR THE IDENTIFICATION OF A NOVEL AUTOSOMAL DOMINANT RETINITIS PIGMENTOSA DISEASE-CAUSING GENE, Jennifer D. Churchill

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Gain-of-function Mouse Models to Investigate Biological Roles of PRMT6, Alessandra Di Lorenzo

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COMBINATION THERAPY WITH AEROSOL IL-2 AND NK CELLS FOR THE TREATMENT OF OSTEOSARCOMA LUNG METASTASIS, Sergei R. Guma

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MODULATED FUNCTIONS OF THE FANCONI ANEMIA CORE COMPLEX, Yaling Huang

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TETHERED IL-15 TO AUGMENT THE THERAPEUTIC POTENTIAL OF T CELLS EXPRESSING CHIMERIC ANTIGEN RECEPTOR: MAINTAINING MEMORY POTENTIAL, PERSISTENCE, AND ANTITUMOR ACTIVITY, Lenka Hurton

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COMPETITION BETWEEN GRB2 AND PLCγ1 FOR BINDING TO FGFR2 REGULATES PHOSPHOLIPASE AND PTEN ACTIVITY, LEADING TO CELL INVASION AND PROLIFERATION, zahra timsah

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Differential regulation of IRESs in the Aurora A mRNA by bFGF through the mTOR complex TORC2 modulates Aurora A kinase expression, Roy L. Voice III

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THE ASSOCIATION BETWEEN THE IL-1 PATHWAY, Isaac C. Wun

Theses/Dissertations from 2013

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INTERACTION BETWEEN BRK AND HER2 IN BREAST CANCER, Midan Ai

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GENOME-WIDE PROFILING UNVEILS CRITICIAL FUNCTIONS OF p53 IN HUMAN EMBRYONIC STEM CELLS, Kadir C. Akdemir

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Development and Characterization of an in vitro Four-species Anaerobic Dental Biofilm Model, Fernando Andrade

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ROLE OF MIR-19A RELEASED BY INFLAMMATORY BREAST CANCER CELLS IN THE REGULATION OF DENDRITIC CELL FUNCTIONS: IN VITRO MODEL OF CROSSTALK IN THE TUMOR MICROENVIRONMENT OF INFLAMMATORY BREAST CANCER, Simone Anfossi

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Novel Imaging-Based Techniques Reveal a Role for PD-1/PD-L1 in Tumor Immune Surveillance in the Lung, Todd Bartkowiak

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NEURAL CORRELATES OF AUDIOVISUAL SPEECH PERCEPTION IN APHASIA AND HEALTHY AGING, Sarah H. Baum

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THE STAPHYLOCOCCUS PSEUDINTERMEDIUS ADHESIN SPSD CONTAINS A CENTRAL FIBRONECTIN-BINDING DOMAIN, Andrea S. Bordt

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A Novel Mechanism of Skin Tumor Promotion Involving Interferon-gamma (IFNγ)/Signal Transducer and Activator of Transcription-1 (Stat1) Signaling in Epidermis, Ronald Bozeman

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Galectin-3 Enhances the Malignant Melanoma Phenotype by Regulating Autotaxin, Russell R. Braeuer

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Evaluating the Utility of Clinical Criteria for the Identification of Lynch Syndrome among Endometrial Cancer Patients, Amanda S. Bruegl

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RNA-SEQUENCING APPLICATIONS: GENE EXPRESSION QUANTIFICATION AND METHYLATOR PHENOTYPE IDENTIFICATION, Guoshuai Cai

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INVESTIGATING THE ROLES OF THE p63 ISOFORMS IN THE MICRORNA BIOGENESIS PATHWAY, Deepavali Chakravarti

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Role of Neurogranin in the regulation of calcium binding to Calmodulin, Anuja Chandrasekar

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Comparison of Tumor Shrinkage and Cumulative Dose Distribution for Lung Cancers, Yi Pei Chen

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Development of HIF-1α/HIF-1β heterodimerization inhibitors using a novel bioluminescence reporter assay system for in vitro high throughput screening and in vivo imaging, Yun-Chen Chiang

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Behavioral responses to methylphenidate: correlations with neuronal activity in the caudate nucleus, Catherine M. Claussen

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Inflammatory Breast Cancer: The Immune Perspective, Evan N. Cohen

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Network Dynamics of Visual Naming, Christopher R. Conner

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ATTITUDES AND PRACTICES OF GENETIC COUNSELORS IN PROVIDING PREDICTIVE TESTING TO MINORS AT RISK FOR LI-FRAUMENI SYNDROME, Allison Copeland

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ATTITUDES TOWARD AND UTILIZATION OF NON-INVASIVE PRENATAL TESTING FOR CHROMOSOME ANEUPLOIDY AMONG OB/GYNS, Jessica Davis

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Mismatch Repair Deficient Tumors Lacking Known Sporadic Causes: Are They All Due to Lynch Syndrome?, Katherine M. Dempsey

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T-CELL TREATMENTS FOR SOLID AND HEMATOLOGICAL TUMORS, Drew C. Deniger

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Renal Cryoablation: Investigation of Periprocedural Visualization Tools and Treatment Response Quantification, Katherine L. Dextraze

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THE MOLECULAR INTERACTION BETWEEN TYPE II DIABETES AND ALZHEIMER’S DISEASE THROUGH CROSS-SEEDING OF PROTEIN MISFOLDING, George A. Edwards III

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Scanned Ion Beam Therapy for Thoracic Tumors, John Gordon Eley

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MOLECULAR AND GENOMIC BASED INSIGHTS INTO THE EVOLUTION OF ENTEROCOCCUS FAECIUM FROM COMMENSAL TO HOSPITAL-ADAPTED PATHOGEN, Jessica R. Galloway-Pena

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A Genomic Approach to Identify The Notch Pathway as a Putative Tumor Suppressor in Endometrial Cancer, Rajshi Gandhi

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BASIS FOR TARGETING MET ACTIVATION MEDIATED RESISTANCE TO PI3K INHIBITION IN BREAST CANCER, Ana M. Gonzalez-Angulo

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STIMULATION THROUGH TLR4 INCREASES FVIII INHIBITOR FORMATION IN A MOUSE MODEL OF HEMOPHILIA A, Claire K. Holley

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Radiogenic Second Cancer Risk Differences in Female Hodgkin Lymphoma Patients Treated with Proton versus Photon Radiotherapies, Kenneth L. Homann

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Evaluation of PRESAGE® dosimeters for brachytherapy sources and the 3D dosimetry and characterization of the new AgX100 125I seed model, Olivia Huang

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Induction of synthetic lethality in mutant KRAS cells for non-small cell lung cancers chemoprevention and therapy, Shaoyi Huang

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Radiomics of NSCLC: Quantitative CT Image Feature Characterization and Tumor Shrinkage Prediction, Luke Hunter

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Characterization of Jak, STAT, and Src interactions in Head and Neck Squamous Cell Carcinoma, Reshma Jaseja and Reshma Jaseja

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INTERACTION OF BACILLUS ANTHRACIS EXOSPORIUM PROTEIN BCLA WITH COMPLEMENT FACTOR H AND SPORE PERSISTENCE IN THE LUNG, Sarah A. Jenkins

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PRKCa: Identification of a Novel Downstream Target of WT1, Devin Jones

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VENTRAL TEGMENTAL AREA NEURONAL RESPONSES TO METHYLPHENIDATE CORRELATED TO BEHAVIORAL RESPONSES OF ADOLESCENT AND ADULT RATS, Zachary Jones

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A NOVEL CARDIAC FUNCTION OF SUMO2/3 AND SENP5 DEPENDENT PATHWAY AND ITS PHYSIOLOGICAL IMPACT ON CONGESTIVE CARDIOMYOPATHY, Eun Young Kim

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C-JUN N-TERMINAL KINASES REGULATE ADENOVIRUS-MEDIATED AUTOPHAGY AND ANTIGEN PRESENTATION, Sarah R. Klein

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THE ROLE AND MECHANISM OF THE HOMEOBOX GENE HOXA9 IN THE GROWTH OF EPITHELIAL OVARIAN CANCER, Song Yi Ko

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Molecular Mechanisms of Vascular Disease in Patients with Rare Variants in MYH11, Callie Kwartler

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EZH2 T416 Phosphorylation Enhances Breast Cancer Tumorigenesis, Adam M. LaBaff and Adam M. LaBaff

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CHARACTERIZATION OF THE ROLE(S) OF ENV PROTEIN OF HUMAN ENDOGENOUS RETROVIRUS-K IN MULTIPLE HUMAN CANCERS, Ming Li

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THERAPEUTIC EFFICACY OF P53 RESTORATION IN MDM2-OVEREXPRESSING TUMORS, Qin Li

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BAYESIAN STATISTICAL METHODS IN GENE-ENVIRONMENT AND GENE-GENE INTERACTION STUDIES, Changlu Liu

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CHARACTERIZATION OF TCL1-Tg:P53-/- MICE THAT RESEMBLE HUMAN CHRONIC LYMPHOCYTIC LEUKEMIA WITH 17P-DELETION, Jinyun Liu

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Targeting Histone deacetylases (HDAC) for the treatment of soft tissue sarcoma, Gonzalo Lopez

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Novel Functions of Cetuximab in EGFR-targeted Therapy: Radiosensitization, Glycolysis Inhibition, and Cellular Redox Status Regulation, Haiquan Lu

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CXCR2 EXPRESSION IN TUMOR CELLS IS A POOR PROGNOSTIC FACTOR AND PROMOTES INVASION AND METASTASIS IN LUNG ADENOCARCINOMA, Erminia Massarelli

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Investigation of Respiratory Motion Management Techniques for Proton and Photon Radiotherapy of Lung Cancer, Jason E. Matney

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STUDYING AGGREGATE FORMATION BY AMYOTROPHIC LATERAL SCLEROSIS-ASSOCIATED MUTANT SOD1 PROTEIN IN DROSOPHILA MODEL, Michael McCarthy

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Knowledge and Expectations of Support People in Prenatal Genetic Counseling Sessions, Michelle A. McDougle

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AN EVALUATION OF THE CONSISTENCY OF IMRT PATIENT-SPECIFIC QA TECHNIQUES, Elizabeth M. McKenzie

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THE IMPACT OF FAMILY HISTORY ON MEDULLARY THYROID CANCER IN MEN2A PATIENTS, Nicole D. Mohrbacher

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DEVELOPMENTAL AND MOLECULAR FUNCTIONS OF PLAKOPHILIN-3, William A. Munoz

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Use of Echogenic Immunoliposomes for Delivery of both Drug and Stem Cells for Inhibition of Atheroma Progression, Ali K. Naji

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Development and implementation of a dynamic heterogeneous proton equivalent anthropomorphic thorax phantom for the assessment of scanned proton beam therapy, James L. Neihart

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Targeted Deletion Of Functionally Validated Enhancers Defines Their Role in Mouse Limb Development, Mark J. Nolte

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INTRODUCING A NOVEL METHOD FOR GENETIC ANALYSIS OF AUTISM SPECTRUM DISORDER, sepideh nouri

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INVESTIGATING APOPTOSIS PATHWAY IN CHRONIC LYMPHOCYTIC LEUKEMIA: STROMAL INFLUENCE AND THERAPEUTIC ACTIVATION, Viralkumar M. Patel

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CHARACTERIZATION OF OSLDS FOR USE IN SMALL FIELD PHOTON BEAM DOSIMETRY, Christopher Pham

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Acceleration of the PanIN Development in Mice Expressing Oncogenic K-Ras Due to a High Fat Diet, Bincy Philip

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CONFORMATIONAL DYNAMICS OF K-RAS AND H-RAS PROTEINS: IS THERE FUNCTIONAL SPECIFICITY AT THE CATALYTIC DOMAIN?, NANDINI RAMBAHAL

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c-REL is a Transcriptional Target of Mesoderm Inducer in Xenopus Like 1 (MIXL1), Aaron C. Raymond

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Delayed Thrombus Resolution and Fibroproliferative Vascular Wound Healing From Deficiency of Type III Collagen: a Paradoxical Mechanism for Tissue Fragility, Amy J. Reid

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αvβ8 Integrin Interacts with RhoGDI1 to Regulate Rac1 and Cdc42 Activation and Drive Glioblastoma Cell Invasion, Steve Reyes

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OXIDATIVE STRESS BASED STRATEGIES FOR ENHANCING THE EFFICACY OF HISTONE DEACETYLASE INHIBITORS (HDACi), Nilsa Rivera-Del Valle

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AN ASSESSMENT OF KNOWLEDGE AND ATTITUDES OF GENETIC COUNSELING SERVICES IN U.S. HTCs, Brad Rolf; Deborah Brown; Miguel Escobar; Syed Hashmi M.D., Ph.D; Aroub Ayham Khleif; Sarah Noblin; and Marianna Raia

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MTORC1 SIGNALING IN MEMORY FORMATION AND DYSFUNCTION, Natalia S. Rozas de O'Laughlin

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The Role of Type I Insulin-Like Growth Factor Receptor Signaling in Breast Cancer Brain Metastasis, Sandra M. Saldana

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Structure-function analysis of human Integrator subunit-4, Anupama Sataluri

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NOVEL INDUCERS OF GLIOTOXIN PRODUCTION IN ASPERGILLUS FUMIGATUS, Taylor J. Schoberle

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NOVEL THERAPEUTIC TARGETS IDENTIFIED BY HIGH-THROUGHPUT TECHNOLOGIES FOR TRIPLE-NEGATIVE BREAST CANCER, Christine Shiang

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Ligand-Directed AAVP to Deliver a Therapeutic Transgene to Neuroendocrine Tumors of the Pancreas, Tracey L. Smith and Tracey Smith

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The Role Of IL-8-Mediated Src Family Kinase Activation In Tumor-Tumor And Tumor-Stromal Interactions In Metastasis Of Prostate Cancer, Lynnelle Thorpe

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INTEGRATIVE BIOMARKER IDENTIFICATION AND CLASSIFICATION USING HIGH THROUGHPUT ASSAYS, Pan Tong

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THE p63 ISOFORM ∆Np63α INHIBITS EPITHELIAL – MESENCHYMAL TRANSITION BY PROMOTING THE EXPRESSION OF MIR-205 IN HUMAN BLADDER CANCER CELLS, Mai Tran

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Characterization of the RNA binding and RNA degrading subunits of the eukaryotic exosome, Borislava Tsanova

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Design, Synthesis and Development of Transporter Targeting Agents for Image-guided Therapy and Drug Delivery, Ning Tsao

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TURNOVER RATE OF THE NEURONAL CONNEXIN CX36 IN HELA CELLS, Yanran Wang

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Mechanisms Underlying the Heterogeneous Sensitivities of Cancer Cells to Proteasome Inhibitors, Matthew C. White

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The Role of Nucleolin in B-cell Lymphomas and Fas-Mediated Apoptotic Signaling, Jillian F. Wise

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The Influence of Immunization Route on the Adjuvant Effect of alpha-Galactosylceramide, Ameerah M. Wishahy

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CHARACTERIZATION OF DIFFERENTIATION AND PROGNOSTIC BIOMARKERS ON CD8+ TUMOR-INFILTRATING LYMPHOCYTES IN METASTATIC MELANOMA, Richard C. Wu

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TRPV1 Channels Contribute to Behavioral Hypersensitivity and Spontaneous Activity in Nociceptors After Spinal Cord Injury, zizhen wu

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THE NATURAL AND ORTHOGONAL INTERACTION (NOIA) MODELS FOR QUANTITATIVE TRAITS (QTs) AND COMPLEX DISEASES, Feifei Xiao

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PIM KINASE INHIBITION: SINGLE AGENT AND COMBINATION APPROACHES IN B-CELL LYMPHOMA, Qingshan Yang

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The Role of K63-linked Ubiquitination Cycles in Akt Kinase Activation, Wei-Lei Yang

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CHARACTERIZING THE EFFECT OF DASATINIB ON ANTI-TUMOR IMMUNE RESPONSE AND EXPLORING THE POTENTIAL OF COMBINING TARGETED THERAPY AND IMMUNOTHERAPY IN A C-KIT MUTANT MASTOCYTOMA MODEL, Yan Yang

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Improving Cervical Cancer Nodal Boost Radiation Therapy by Quantifying Uncertainties and Exploring Advanced Radiation Therapy Modalities, Zhiqian Yu

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Altered ovarian cancer metabolism increases neuronal n-acetylaspartate to promote tumor growth, Behrouz Zand