Digital dissertations from 1966-2009. Free access is limited to the HAM-TMC community; others may be able to access them through their own libraries or purchase them from ProQuest. For remote access click here.

Dissertations from 2009-current are available open-access here

Older UT GSBS dissertations (approximately 1979-1999) are available in print-format only and are available in the HAM-TMC Library. They're listed in the Library Catalog under the subject heading: "Dissertations, Academic--University of Texas Health Science Center at Houston. Graduate School of Biomedical Sciences."

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Submissions from 2009

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11beta-hydroxysteroid dehydrogenases as regulators of pulmonary corticosterone during the granulomatous response to trehalose 6,6'-dimycolate, April Nicole Abbott

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The role of IL-25 in allergic lung disease, Pornpimon Angkasekwinai

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Src takes center stage in chronic stress-induced tumor growth, Guillermo Nicolas Armaiz-Pena

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Identification of a conserved cluster in the RH domain of GRK critical for activation by GPCRs, Faiza Baameur

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Why does low dose morphine augment fentanyl analgesia?, Katherine Elaine Barker

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Molecular consequences of the loss of 3'→5' exonuclease activity of DNA polymerases delta and epsilon, Rina Bhagat

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Mechanisms by which nonsense codons downregulate T-cell receptor transcripts, Angela Bhalla

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Identification and characterization of virulence determinants in the Lyme disease spirochete Borrelia burgdorferi, Douglas John Botkin

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A dual oxidase generates a protective oxidative burst during infection in C. elegans, Violeta Chavez

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Roles of PI3K/Akt activated MDM2 and p21 in mammary development and tumorigenesis, Xiaoyun Cheng

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Genetic variations in the PI3K-AKT-mTOR pathway and bladder cancer susceptibility and clinical outcomes, Meng Chen

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Role of ovarian cancer antigen CA125/MUC16 in development and cancer, Dong-Joo (Ellen) Cheon

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The role of AKT-mediated phosphorylation in suppression of MAD1 and the development of new approach in protein complex detection, Chao-Kai Chou

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Establishment of a complex inflammatory and protumorigenic microenvironment in mouse pancreas through cyclooxygenase-2 overexpression, Jennifer Kay Long Colby

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Cryo-electron tomography and single-particle cryo-electron microscopy: Structures of Kaposi's sarcoma-associated herpesvirus and propionyl-CoA carboxylase, Binbin Deng

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Involvement of lipocalin 2 in leukemia and breast cancer, Tian Ding

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The role of ATM in the cell cycle control of V(D)J recombination, Melanie Elizabeth Dujka

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Roles of insulin-like growth factor binding protein-3 in gastrointestinal stromal tumors, Jheri J Dupart

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A systematic analysis of INO80 in DNA replication, Karina Beatriz Falbo

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The effects of antipsychotic medications on eye movements in schizophrenia, Shelby Babin Fontenot

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Mechanisms of transcription inhibition by 8-amino-adenosine, Jennifer Frey

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The eukaryotic cellular stress response: Biochemical and genetic analyses in Saccharomyces cerevisiae, Patrick Allen Gibney

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E2F1's role in ultraviolet-induced DNA damage response, Ruifeng Guo

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Dynamic population coding in primary visual cortex, Diego Gutnisky

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The transcriptional repressor Delta EF1 controls resistance to the EGFR inhibitor erlotinib in human HNSCC lines, Yasmine Haddad

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Identification and characterization of an optimal three-dimensional dosimetry system for remote auditing by the RPC, Malcolm P Heard

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Effects of treatment on orienting in Parkinson disease, Ashley Jagar Hood

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Nonsense-mediated decay: A branched and regulated pathway, Lulu Huang

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From protein microarray to biology: The discovery of epigenetic regulatory molecules, Aimee Nicole Iberg

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The INO80 chromatin remodeling complex is involved in the nucleotide excision repair pathway, Yingjun Jiang

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Spatial and temporal aspects of synaptic plasticity, Georgios Kalantzis

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Trehalose 6,6'-dimycolate promotes the survival of Mycobacterium tuberculosis in murine macrophages, Celestine Wing-Wah Kan-Sutton

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Elucidating the role of mesenchymal stem cell participation in the tumor microenvironment, Shannon Michelle Kidd

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Role of activation of the protein tyrosine kinase, Src, in colorectal cancer chemoresistance, Edmund Scott Kopetz

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ARD1 stabilization of TSC2 suppresses tumorigenesis via the mTOR signaling pathway, Hsu-Ping Kuo

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The role of reactive astrocytes in the resistance of melanoma brain metastasis to chemotherapy, Qingtang Lin

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The critical role and regulation of transcription factor FoxM1 in gastric cancer development and progression, Qiang Li

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Triplex-forming oligonucleotide directed psoralen interstrand crosslinks can induce targeted homologous recombination in mammalian cells, Yaobin Liu

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Coordination of murine limb muscle, skeleton and connective tissue development by Lmx1b, Ying Li

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Macromolecular interaction studies on FF1-3 of human CA150 and STAT1-importin alpha5 using biophysical and biochemical methods, Ming Lu

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Organization of the inferotemporal cortex in the macaque monkey: Connections of areas PITv and CITvp, Evelyn McClendon

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Caspase 8: Mediating the effects of a novel proteasome inhibitor, NPI-0052, Claudia Patricia Miller

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Membrane trafficking from lysosomes to the plasma membrane regulates phosphatidylserine externalization during apoptosis, S. Banafsheh Mirnikjoo

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NHERF1 recruits the tumor suppressors PTEN and PHLPP to synergistically inhibit the PI-3K pathway, Jennifer Rosario Molina

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Organization and function of platelet glycoprotein Ib-IX complex, Xi Mo

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DNA methylation inhibits p53 mediated survivin repression in cancer cells, Nancy H Nabilsi

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The survival role and the potential therapeutic targeting of MET in multiple myeloma, Cornel Phillip

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Alterations in cell adhesion and migration are transcriptionally regulated by the tumor suppressor, TP53, Nicole Lynn Pinaire

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Alternative carbon metabolism: Virulence and regulation in Candida albicans, Melissa Ann Ramirez

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Anti-glomerular basement membrane glomerulonephritis: Characterization of an epitope, antibody response, and the potential role of IL-4Ralpha in disease progression, Julie Milayna Robertson

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Regulation of two P450 isoforms: CYP2D6 and CYP4F11, Daniel J Ryder

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Antigen-specific proteolytic antibodies, Gopal Sapparapu

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The role of plasmacytoid dendritic cells in the regulation of adaptive immunity, Joanne Louise Shaw

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Mechanism of methylation gene reactivation in human cancer cells, Jiali Si

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Transcriptional and translational regulators of gene expression in germ cell development, Hye-Won Song

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Investigating the pathogenicity of mutations in two ubiquitously expressed housekeeping genes that cause autosomal dominant retinitis pigmentosa, Catherine Jean Spellicy

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In vivo longitudinal studies of spinal cord injury and vascular endothelial growth factor treatment, Laura Michelle Sundberg

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The role of beta-arrestin 2 in lysophosphatidic acid-induced NF-kappaB activation, Jiyuan Sun

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Regulation of chromatin structure, Smad binding and AFP expression by the Forkhead box transcription factor: Foxa1, Joseph Harvey Taube

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The cellular and molecular responses to a novel nucleotide analogue, GS-9219, Cheng-Yu Tsai

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Molecular mechanisms by which p53/LSD1 and ERalpha/Trim24 complexes mediate gene regulation, Wen-Wei Tsai

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Protease-activated receptor-1 signaling plays a major role in melanoma growth and metastasis, Gabriel Jose Villares

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Identification and characterization of mutations in SMC contractile genes involved in thoracic aortic aneurysms and dissections, Li Wang

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Characterization of cytochrome P450 4F subfamily: Response in traumatic brain injury and gene regulation, Ying Wang

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Therapeutic potential of p53 restoration in spontaneous tumors, Yongxing Wang

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A blood-borne PDGF/VEGF-like ligand initiates wound-induced epidermal cell migration in Drosophila larvae, Yujane Wu

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Identification of essential apoptotic genes in Drosophila, Dongbin Xu

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Polycomb repressive complex 2 and induced basal-like breast cancer phenotype mediated by cyclin E/Cdk2, Chen-Chieh Yang

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A new fork for clinical application: Targeting forkhead transcription factors in cancer therapy, Jer-Yen Yang

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Transcriptional regulation of lung tumor suppressor GPRC5A in malignant and normal cells, Xiaofeng Ye

Submissions from 2008

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Emerging roles for the double strand break repair protein 53BP1 in transcriptional regulation, Melissa Marie Adams

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Characterization of Staphylococcus aureus adhesins important for respiratory tract infection, Elena Magdalena Barbu

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Diversity in T cell costimulation by alpha4beta1 integrin, Matthew John Billard

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EphA2 expression is regulated by EGFR and KRAS and promotes non-small cell lung cancer progression, Jennifer Mary Brannan

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Acetate metabolism and the control of environmental pH in Candida albicans and Saccharomyces cerevisiae, Aaron J Carman

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SFRP4 regulation of Wnt7a signaling and cellular proliferation in the endometrium, Kendra S Carmon

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Beta-catenin in testicular development and tumorigenesis, Hao Chang

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A novel mechanism of 3-bromopyruvate-induced cell death through targeting hexokinase and ubiquitination, Zhao Chen

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Glioma-specific alternative RNA splicing: A role for polypyrimidine tract binding protein-1, Hannah Chung-yan Cheung

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Role of telomere dysfunction, DNA damage response and p53 mutations in tumorigenesis and aging, Wilfredo Cosme-Blanco

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The molecular mechanisms of sensing nucleoside analogue-induced DNA damage, Brett J Ewald

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Proton therapy versus intensity modulated x-ray therapy in the treatment of prostate cancer: Estimating secondary cancer risks, Jonas David Fontenot

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Anticancer activity of OSW-1: Induction of apoptotic pathway in leukemia and autophagic death in pancreatic cancer through a calcium mediated mechanism, Celia Garcia-Prieto

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CARMA3 serves as a critical mediator of NF-kappaB in multiple signal transduction pathways, Brian Chandler Grabiner

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The mechanism of action of a novel benzo[c]phenanthridine alkaloid, NK314 and the cellular responses, Lei Guo

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An integrated molecular biology and computational approach to CYP1A1 expression in human brain, Jade Michelle Hatley

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Identification and analysis of novel mitotic inhibitors of the Caenorhabditis elegans Aurora B kinase, Todd Ryan Heallen

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Ligand-stimulated internalization of a Dictyostelium discoideum G protein-coupled cAMP receptor, Mark Richard Hickman

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CARD9 functions as a key regulator in monocyte homeostasis and pathogen clearance, Yen-Michael Sheng Hsu

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Alterations in redox and energy metabolism in Ras-transformed cells: Mechanisms and therapeutic implications, Yumin Hu

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Downstream targets of the Rhox5 homeobox gene, Zhiying Hu

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Reactive oxygen species-dependent mechanisms of N-(4-hydroxyphenyl)retinamide (4HPR)-induced apoptosis in human carcinoma cells, Humam Kadara

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Forebrain-cerebellum interactions revealed by trace eyelid conditioning, Brian Edward Kalmbach

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Mechanotransduction pathway activation in familial thoracic aortic aneurysms and dissections, Andrea Lee Lafont

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Involvement of HMGB1 in the repair of DNA adducts and the responses to DNA damage in mammalian cells, Sabine Sue Lloyd Lange

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Role of IkappaB kinase beta in inflammation-mediated breast cancer development, Dung-Fang Lee

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Analysis of the E1-ubiquitin activating enzyme, Uba1, in cell death and tissue growth in Drosophila, Tom Van Lee

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Oncogenic activation of c-Abl tyrosine kinase in non-small cell lung cancer: FUS1 tumor suppressor down-regulates c-Abl tyrosine kinase, Jacki Lin

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Dissecting the role of LIM-homeobox gene LMX1B in the development of the ocular anterior segment, Pu Liu

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14-3-3 zeta mediated epithelial-mesenchymal transition (EMT) contributes to ErbB2 overexpressing ductal carcinoma in situ (DCIS) progression into invasive breast cancer, Jing Lu