Digital dissertations from 1966-2009. Free access is limited to The TMC Library's academic-level users; other users may be able to obtain them through their own libraries or purchase them from ProQuest. For remote access click here.

Dissertations from 2009-the present are open-access here in DigitalCommons@TMC.

Older UT GSBS dissertations (dating approximately 1979-1999) are available at The TMC Library in print format. Check the Library Catalog. For best results, search using the subject heading: "Dissertations, Academic--University of Texas Health Science Center at Houston. Graduate School of Biomedical Sciences."

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Submissions from 2008

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Mitochondrial dysfunction leads to NOX activation: A novel mechanism to maintain high glycolysis in cancer cells, Weiqin Lu

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Spectroscopic and functional investigations of the AMPA subtype of ionotropic glutamate receptors, Kimberly Anne Mankiewicz

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Characterization of humoral immune responses against Treponema pallidum antigens, Melanie Ann McGill

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Vital function for PRELI and essential requirement for its LEA motif, Morgan Rouse McKeller

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The role of the cap and poly(A) tail in mRNA metabolism, Stacie Ann Meaux

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Studies of pseudoachondroplasia chondrocytes and knockdown of the cartilage oligomeric matrix protein, Thomas M Merritt

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In-vivo diffusion tensor imaging of rat spinal cord with a phased array coil at 7T, Venkata Kishore Mogatadakala

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Functional architecture of mammalian horizontal cells, Feng Pan

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The role of SRC family kinase activation in prostate cancer growth and lymph node metastasis, Serk In Park

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Scaffolding of adenylyl cyclase by A Kinase Anchoring Proteins, Leslie Ann Piggott

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Antibody chemical reactivity: Beneficial and pathogenic roles, Stephanie Andree Planque

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Characterization of the interactions between fibronectin and the Borrelia burgdorferi lipoprotein, BBK32, Sabitha Prabhakaran

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The imaging and dosimetric capabilities of a CT/MR-suitable, anatomically adaptive, shielded intracavitary brachytherapy applicator for the treatment of cervical cancer, Michael Price

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Maximizing efficacy of the hypomethylating drug 5-aza-2'-deoxycytidine in human leukemia, Taichun Qin

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Molecular mechanism of jet fuel induced immune suppression, Gerardo Ramos

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Depolarization-dependent synaptic potentiation and hyperexcitability induced by a Ca2+-independent trigger, Fredy D Reyes

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Role of T cell response during vaccine immunity to tuberculosis, Cherie Michelle Roche

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cAMP regulates IL-2 receptor signaling in human T cells, Georgialina Rodriguez

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The molecular basis for beta-lactamase gene expression in B. anthracis, B. cereus and B. thuringiensis, Cana Lynn Ross

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The regulation of JAB1 and its role in herceptin resistance, Terry Jo Shackleford

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Regulation of estrogen receptor alpha by the tumor suppressor p53 in breast cancer cells, Stephanie Harkey Shirley

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The effect of DNA methylation in carcinogenesis, Jingmin Shu

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Evaluation of the C5a anaphylatoxin and its receptor (CD88) in allergic lung disease, Meenal Sinha

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Contribution of transmembrane and cytoplasmic domains to membrane protein association, Sankaranarayanan Srinivasan

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Selective elimination of cancer cells by PEITC: Biological basis and therapeutic implications, Dunyaporn Trachootham

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The role of MEKK3 in T cell homeostasis and IFNgamma production, Xiaofang Wang

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EGFR and Notch signaling pathways are regulated by distinct isoforms of Drosophila cbl, Yuan Wang

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Structures of thromboxane A2 receptor intracellular domain and Galphaq C -terminal domain: Their roles in receptor-G protein coupling, Jiaxin Wu

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S100A4 is a molecular mediator of endometrial carcinoma invasion, Ran Xie

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Functional analysis of BLAP75, a BLM-associated protein, Chang Xu

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Protecting blood -brain barrier integrity following traumatic brain injury, Jing Zhao

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Impact of COP9 signalosome subunit 6 (CSN6) on MDM2-p53 axis in DNA damage-mediated apoptosis and tumorigenesis, Ruiyang Zhao

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Regulation of Alix by an autoinhibitory intramolecular interaction, Xi Zhou

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G870A polymorphism of cyclin D1 gene influences cancer risk - From epidemiological study to mechanism analysis, Jing Zhu

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Identification of germ cell tumor modifier genes from the 129.MOLF-Chr19 consomic mouse strain, Rui Zhu

Submissions from 2007

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Preclinical modeling of multi-drug cancer therapies, John C Boik

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High-resolution microarray analysis of chromosome 20q in human colon cancer metastasis model systems, Jennifer Lee Carter

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T -cell receptor nonsense-associated altered splicing, Yao-Fu Chang

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Homeostatic transcriptional regulation of bcl-2 in the epidermis, Nikhil S Chari

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Identification and functional characterization of novel phosphotyrosine and phosphoserine residues in the interleukin-2 receptor complex, Hanyin Cheng

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Thoracic cancer imaging with PET /CT in radiation oncology, Pai-Chun Melinda Chi

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Characterization of glucocorticoid receptor (NR3C1) gene polymorphisms and a family-based association study with hypertension, Charles C Chung

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14-3-3 zeta overexpression in early stage breast disease and tumor progression, Christopher George Danes

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Examination of the engraftment of exogenous mesenchymal stem cells in ovarian tumors and their potential use as delivery vehicles for therapeutic genes, Jennifer L Dembinski

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Insulin-like growth factor binding protein 2 (IGFBP2) promotes glioma development and progression, Sarah M Dunlap

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Characterization of tumor-associated Foxp3+ regulatory T cells and de-novo induction by the tumor microenvironment, Omar Duramad

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BLyS/BAFF-R signaling pathway in human aggressive non Hodgkin's lymphoma B cell and normal peripheral blood B lymphocytes, Lingchen Fu

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Mouse retinal development: Role of cell adhesion and mechanism of gene regulation, Xueyao Fu

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Cis-acting elements and developmental regulators govern toxin gene expression in Bacillus anthracis, Maria Hadjifrangiskou

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The connection between E2F and ATM in p53-dependent apoptosis, Sung Ki Hong

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The role and mechanism of supressor of cytokine signaling 1 in brain metastasis, Feng-Ju Huang

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Post-transcriptional regulation of human pulmonary surfactant protein B (SP-B) mRNA, Helen Wan-ching Huang

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Regulation of RNA splicing by nonsense mutations, J. Saadi Imam

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Hypoxia-induced transcriptional regulation through chromatin modifications and NC2 function, Amber Johnson

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The development and validation of a Monte Carlo model for calculating the out -of -field dose from radiotherapy treatments, Stephen Kry

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Identification of genetic variation influencing apolipoprotein E levels: Follow-up of genome-wide linkage scans in the GENOA study, Magalie Sophie Leduc

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CCAAT -binding factor (CBF) function in endoplasmic reticulum stress response, Rong Luo

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Expression study of the atherosclerosis mouse aorta reveals significant disturbance of calcium signaling pathway, Solida K Mak

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New insights into the role of the duodenal vitamin D receptor in calcium homeostasis, Hilary Diane Marks

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Using in vivo diffusion -weighted MRI to quantify treatment response in murine tumors, Rebecca Milman Marsh

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Molecular mechanisms of response in gastrointestinal stromal tumors treated with imatinib mesylate, John Christopher McAuliffe

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Near infra-red-activatable nanocarriers for selective cancer diagnosis and treatment, Marites Pasuelo Melancon

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Regulation of poly -c -RNA binding protein 1 functions by Pak1 signaling, Qingchang Meng

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Effects of early and late lesion of orbital frontal cortex on visual processing of faces in rhesus macaques (Macaca mulatta), Eugena Pixley Mitchell

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The differential staurosporine mediated G1 arrest in normal versus tumor cells is dependent on the retinoblastoma and Chk1 proteins, Mollianne McGahren Murray

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Reduction of setup uncertainties and tumor motion in the radiation therapy of lung tumors, Christopher Lee Nelson

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Life and death of the embryonic female reproductive tract, Grant Donovan Orvis

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The role of STAT3 in the emergency neutrophil response, Anthanasia Demetra Panopoulos

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Stem -like cancer cells in human cell lines and xenografts: Identification and characterization, Lubna Patrawala

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Molecular interactions and signal transfer between sensory rhodopsin-I and its cognate transducer, Brian James Phillips

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Identification and characterization of distinct classes of cAMP-pulse-induced genes in Dictyostelium discoideum development, Jason Mathew Rall

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Bone marrow-derived stem/progenitor cells play an important role in the growth of Ewing's sarcoma tumors, Krishna Reddy

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The role of CD1d in adipogenesis, Corina Rosales

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Proteomic identification and functional characterization of prohibitin 1 and 2 in T cell activation, expansion, survival and disease, Jeremy Aaron Ross

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The roles of costimulatory molecules in the cooperative effects of combination epinephrine and dexamethasone on type-1/type-2 cytokine production in tetanus-toxoid specific stimulated human peripheral blood mononuclear cells, Adriano N Salicru

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Ser88 phosphorylation regulates dynein light chain 1 (DLC1) function in the mouse mammary gland, Chunying Song

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Identification and characterization of new genes involved in Drosophila heart development, Ye Tao

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The p53 pathway in the homeostasis of the intestinal epithelium, Yasmine A Valentin-Vega

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ERK-MAPK-mediated activation of CDC25 during G2 /M transition, Ruoning Wang

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Electron intensity modulation for mixed-beam radiation therapy with an x-ray multi-leaf collimator, Rebecca Weinberg

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Long-term hyperexcitability of sensory and motor axons in Aplysia californica: Induction by axotomy, serotonin, and transient depolarization, Ramal Majintha Silva Weragoda

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Tumor suppressor cross-talk: The p53 and TGFbeta pathways converge to repress gene transcription, Deepti Srinivas Wilkinson

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Adaptation and maladaptation of heart and skeletal muscle to different diets in a rodent model of human obesity, Christopher Robert Wilson

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Understanding the molecular mechanisms of nonstop mRNA metabolism in Saccharomyces cerevisiae, Marenda Wilson

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The low molecular weight (LMW) isoforms of cyclin E provide a novel mechanism of cell cycle deregulation, Hannah Wingate

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Roles of IkappaB kinase alpha in centrosome duplication and skin carcinogenesis, Xiaojun Xia

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Studies on behavioral regulations of morphine tolerance in rats, Jijun Xu

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Functional differences of beta-tubulin isotypes: A study of microtubule assembly and antimitotic drug resistance, Hailing Yang

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The relationship of mutations in alpha- and beta-tubulin to microtubule assembly and anti-mitotic drug resistance, Shanghua Yin

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The expression and functional roles of the actin filament -associated protein AFAP-110 in human prostate carcinoma, Jing Zhang

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The effects of proteasome inhibition on angiogenesis and autophagy in human prostate cancer cells, Keyi Zhu

Submissions from 2006

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A physiological role of cytochromes P450 4Fs: Mouse model, Leposava Antonovic

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Neuronal plasticity in relation to long -term memory for sensitization in Aplysia, Evangelos G Antzoulatos

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Mdm2 and Mdm4 control distinct p53 functions that cooperate in suppression of tumorigenesis, Juan Antonio Barboza

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The interaction between Bcl-6 and STAT6 pathway in non -Hodgkin lymphoma, Kimberly Diane Bunce

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Osterix inhibits bone destruction in osteosarcoma through transcriptional repression of Interleukin-1alpha expression, Ying Cao

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The roles of UPF3a and UPF3b in nonsense mediated decay, Chan Wai-kin

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Comparative studies of Hox genes in mammalian limb and vertebral pattern formation, Chih-Hsin Chen

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GMZ27 is a new organic arsenic derivative with anti-leukemic activity, via the induction of reactive oxygen species through NADPH oxidase and mitochondrial pathway that lead to leukemia cell apoptosis, Xiaodong Cheng

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Lethal giant discs, a novel C2 domain protein, restricts Notch activation during endocytosis, Jennifer Lauren Childress