Digital dissertations from 1966-2009. Free access is limited to The TMC Library's academic-level users; other users may be able to obtain them through their own libraries or purchase them from ProQuest. For remote access click here.

Dissertations from 2009-the present are open-access here in DigitalCommons@TMC.

Older UT GSBS dissertations (dating approximately 1979-1999) are available at The TMC Library in print format. Check the Library Catalog. For best results, search using the subject heading: "Dissertations, Academic--University of Texas Health Science Center at Houston. Graduate School of Biomedical Sciences."

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Submissions from 2006

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Adenosine induced pulmonary fibrosis and the contribution of the adenosine A2B receptor to the induction of osteopontin in a mouse model of pulmonary fibrosis, Janci Lee Chunn

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Developmental programming of tumor suppressor gene penetrance, Jennifer DeAnn Cook

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Subcellular targeting of and protein -protein interaction within the bacterial cell division complex, Brian Dale Corbin

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Generation of an hTERT-restricted, CMV-augmented oncolytic adenovirus capable of tumor-specific transgene expression: Development, characterization, and optimization, John Joseph Davis

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Nuclear functions of dynein light chain 1 in hormone action, Petra den Hollander

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Non B-DNA structures and genomic instability associated with myotonic dystrophy type 2 (CCTG).(CAGG) repeats, Sharon Patricia Fernandez Edwards

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Mechanisms of heterosynaptic modulation of transmission in Aplysia, Diasinou Fioravante

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Identifying the roles of the Escherichia coli FtsZ-associated proteins by minimizing the requirements for division, Brett Lawrence Geissler

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A novel role for neural crest cells in thymus organogenesis, Ann Venables Griffith

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Hypersensitive granulomatous response to mycobacterial glycolipid trehalose 6,6'-dimycolate, Tera Vale Guidry

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Transcriptional upregulation of the p21Cip1 promoter by STAT3 and nuclear ErbB2, Valerie Stone Hawthorne

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Radical S -adenosyl methionine domain containing-1 (rsad1): A novel gene essential for cell survival during vertebrate development, Raegan D Hunt

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Lactoferrin: An adjuvant to enhance the efficacy of the BCG vaccine, Shen-An Hwang

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Novel molecular insights into human tooth agenesis, Hitesh Kapadia

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Whole genome analysis of Fusobacterium nucleatum, Rickettsia typhi and Francisella tularensis, Sandor Ervin Karpathy

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The transcription factor nuclear factor kappa B (NFkappaB) maintains TRAIL resistance in human pancreatic cancer cells, Sanaz Khanbolooki

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Modifiers of mammary tumorigenesis in p53 heterozygous mice, Joanna Gail Koch

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Monte Carlo and analytical dose calculations for ocular proton therapy, Nicholas Corey Koch

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Requirement of GCN5 histone acetyltransferase in mouse neural tube closure and skeletal patterning, Wenchu Lin

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Analysis of Wnt/beta-catenin signaling in kidney tubulogenesis, Jon P Lyons

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The genetic contribution of the major histocompatibility complex to bleomycin-induced lung injury, Suneil Singh Malhotra

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Regulation of T cell function by complement C5A in mice during mycobacterial infection, Mary Anne Mashruwala

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Investigation of the molecular mechanisms of endometrial hyperplasia, Adrienne Williams McCampbell

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Abnormal expression of E2F1 and E2F4 results in hyperproliferation of the ependyma and lethal hydrocephalus, Diana R Medrano

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T cell adhesion regulation from clustering GM1 lipid rafts, Jason Sterling Mitchell

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The role of adenosine in pulmonary angiogenesis, Amir Mohsenin

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Ligand-directed targeting of malignant gliomas, Catherine Moya

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Proactive aggression: A two part study, Sylvain Olivier Nouvion

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Diversity of neuronal connexins in the mammalian retina, Jennifer Jane O'Brien

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Image -guided adaptive radiotherapy for prostate and head-and-neck cancers, Jennifer C O'Daniel

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The role of deregulated E2F1 expression in brain tumors, Melissa Vinores Olson

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Mechanism of IFN-induced apoptosis and sensitization by the proteasome inhibitor bortezomib in bladder cancer cells, Paraskevi Angeliki Papageorgiou

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Radiosensitization of human cancer cell lines in vitro by genetic targeting of Ku70 and the PI3 -kinase/Akt pathway, Gus Pappas

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The p120-catenin/Kaiso signaling pathway, Jae-il Park

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Negative regulation of Drosophila Transformer2 by SR splicing factors, Junlin Qi

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Insights into the biology of lymphatic metastasis, Robert B Rebhun

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The effects of proteasome inhibition in chronic lymphocytic leukemia and prostate cancer, Stacey Lynn Ruiz

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Caenorhabditis elegans germinal center kinase (Gck-1) is a p-body component that inhibits precocious ectopic MAP kinase dependent meiotic maturation, Katherine Roeder Schouest

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Biochemical and genetic characterization of the Saccharomyces cerevisiae Hsp110 molecular chaperone Sse1, Lance Mercer Shaner

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The in vivo and in vitro formation of sticky DNA and the GAA.TTC trinucleotide repeat associated with Friedreich's ataxia, Leslie Spitz Son

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Tp53-dependent repression of cell cycle target genes: Global and mechanistic analysis, Kevin Bradford Spurgers

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Investigations of stress responses in Saccharomyces cerevisiae: Transcriptional control and heat shock protein function, Amy Elizabeth Trott

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New cytochromes P450: Tale of two variants, Cheri Marie Turman

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Dysregulation of alternative splicing of coagulation factor V results in bleeding disorder, east Texas type and other disorders of hemostasis, Lisa Marie Vincent

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The role of ecto -5' -nucleotidase (CD73) in lung injury, Jonathan Barnard Volmer

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A mechanism of insulin-like growth factor binding protein 2-induced cell mobility in glioma, George K Wang

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The role of 14-3-3 sigma in the c -Myc -Pin1 complex: Impacting upon the c-Myc degradation process and c-Myc-induced DNA damage, Yu-Ye Wen

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Chimpanzee: A predictive model for the human cytochrome P450 3A subfamily, Eric Trey Williams

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Integrating sequence information in microarray data analysis by free energy modeling, Chunlei Wu

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Roles of mismatch repair proteins in the recognition and processing of DNA interstrand crosslinks in human cells, Qi Wu

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p21 activated kinase 5 links multiple GTPase signaling pathways at mitochondria, Xiachong Wu

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Mitogen -activated protein kinase kinase-4 maintains cell survival through NFkappaB-dependent inhibition of PTEN gene expression, Dianren Xia

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Lipid-dependent topogenesis and function of membrane proteins, Jun Xie

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The role of coactivator associated arginine methyltransferase 1 (CARM1) in nuclear receptor mediated transcription, Neelu Hariram Yadav

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Metastatic lung cancer in a new mouse model inheriting p53 and latent K-ras mutations, Shuling Zheng

Submissions from 2005

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Respiratory rhythm generation: A modeling study of the respiratory central pattern generator and the phrenic motor neuron, Behrang Amini

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Female-specific regulation of cytochrome P450 3As and their response to xenobiotic stress, Sayeepriyadarshini Anakk

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RNA polymerase II large subunit degradation induced by ecteinascidin 743: Molecular characterization and subsequent rational investigation of antitumor mechanisms in cancers with clinical response, Gregory J Aune

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Targeted cancer diagnosis with radiolabeled endostatin, Ali Azhdarinia

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The role of functional tumor suppressor 15-lipoxygenase 2 (15-LOX2) in normal human prostate epithelial cells and prostate cancer development, Bipin Bhatia

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Cellular and molecular mechanisms of hippocampus-dependent long -term memory, Sonja Blum

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An Sp1/Sp3 site polymorphism associated with hypermethylation of the candidate tumor suppressor gene RIL in cancer, Yanis A Boumber

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Mitochondrial defects in primary leukemia cells: Biological consequences and therapeutic implications, Jennifer Sue Carew

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Assessment of cone beam computed tomography techniques for imaging lung damage in mice in vivo, Dawn Cavanaugh

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Targeting dysregulated nuclear proteins androgen receptor and enhancer of zeste homolog 2: Clinical implication and mechanism underline, Tai-Lung Cha

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Breast cancer -specific activation of topoisomerase IIalpha and its application in the tumor -targeting gene therapy, Chi-Ping Day

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Xp95 is phosphorylated within the proline rich domain during Xenopus oocyte maturation, Robert Edward Dejournett

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Esx1 dosage impacts reproductive fitness: Effects on viability and fertility, Laurel E Fohn

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Immune restoration of patients with chronic myelogenous leukemia in complete cytogenetic remission, Hui Gao

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Defective antitumor function of monocyte -derived macrophages from epithelial ovarian cancer patients, Ilyssa Okrent Gordon

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A conditional Mdm2 allele shows the importance of Mdm2 in heart development, Jason Dwain Grier

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Role of entorhinal cortical plasticity in spatial and contextual memory, April Ethel Hebert

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DNA incisions stimulate genetic instability of triplet repeat sequences related to human hereditary neurological diseases, Micheal Lee Hebert

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Effect of thiazolidinedione, a class of anti-diabetic drugs, on the mouse skin tumorigenesis, Guobin He

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The function of the murine complement *C3a and *C5a anaphylatoxin receptors in endotoxemia, bacteremia and septic shock, Travis J Hollmann

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Analysis of Agrobacterium tumefaciens VirB6 and VirB9 of the VirB /D4 type IV secretion system, Simon Jan Jakubowski

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Characterization of cytochrome P450 4F subfamily: Functional role and response in inflammation, Auinash Kalsotra

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p16-induced apoptosis in Ewing's sarcoma, Geoffrey Sumithran Kannan

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High -avidity PR1-specific CD8+ lymphocytes contribute to the maintenance of remission in patients with myeloid leukemia, Shreya Kant

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Upregulation of VEGF through p70S6K in ErbB2 -mediated angiogenesis and inhibition by combined herceptin plus taxol therapy, Kristine Sue Klos

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Analyzing the function of myogenin in adult satellite cells through the construction of a myogenin conditional allele, Jennifer Rebecca Knapp

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Tackling ErbB2: ErbB2-targeting peptide therapy and combination therapy with trastuzumab plus PI3K inhibitors, Keng-Hsueh Lan

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Bortezomib modulates TRAIL sensitivity in human bladder and prostate cancer, Laura Michelle Lashinger

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DNA vaccination against the novel tumor antigen, MUC18, for the therapy of metastatic melanoma, Michael Clinton Leslie

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Expression regulation of AP -2 gamma gene, Mei Li

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Cellular mechanisms of operant and classical conditioning, Frederick D Lorenzetti

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POU domain transcription factor Brn3b is critical for the normal development and survival of retinal ganglion cells, Suzanna Elizabeth Martin

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Function of GCIP (CCNDBP1), a helix -loop -helix leucine -zip protein, in cell differentiation and tumorigenesis, Wenbin Ma

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The biologic and signaling effects of Tiam1 overexpression in colorectal carcinoma, Meghan Elizabeth Minard

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Elucidation of the role of 53BP1 in DNA double strand break (DSB) repair and tumor suppression, Julio Cesar Morales

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IL -24; a glycosylated dimeric cytokine affecting monocytes and cytotoxic to melanoma cells, John Mumm

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Molecular genetic analyses of extracellular signaling pathways during murine retinal development, Deepa Murali

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Induction of endoplasmic reticular stress by bortezomib: A novel therapeutic strategy for pancreatic cancer, Steffan Todd Nawrocki

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Mechanisms involved in suppression of the elicitation of immune responses by ultraviolet light, Dat Xuan Nghiem

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Molecular mechanism of the relaxin signaling pathways: Activation of cAMP, PI3K, and PKCzeta, Bao The Nguyen

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The role of interleukin-6 in the angiogenesis of ovarian carcinoma, Monique Boagni Nilsson

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Roles of Alix in regulating cell morphology, Shujuan Pan

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Dysregulated CD40-NF-kappaB signaling in the pathophysiology of aggressive non -Hodgkin's lymphoma B cells, Lan Pham

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Multiple gradient echo propeller (MGREP) MRI: Technical development and potential applications, Aziz Hatim Poonawalla

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The role of Lmx1b in the control of dorsoventral compartmentalization in the distal mesenchyme of the developing mouse limb, Qiong Qiu