UT GSBS Dissertations (via ProQuest)
Digital dissertations from 1966-2009. Free access is limited to The TMC Library's academic-level users; other users may be able to obtain them through their own libraries or purchase them from ProQuest. For remote access click here.
Dissertations from 2009-the present are open-access here in DigitalCommons@TMC.
Older UT GSBS dissertations (dating approximately 1979-1999) are available at The TMC Library in print format. Check the Library Catalog. For best results, search using the subject heading: "Dissertations, Academic--University of Texas Health Science Center at Houston. Graduate School of Biomedical Sciences."
Submissions from 2003
Using K5 Myc transgenic mice to delineate *Myc's apoptotic and tumorigenic pathways, Robert J Rounbehler
Role of the transcription factor activator protein-2alpha in prostate carcinogenesis, Maribelis Ruiz Vega
Gene regulation during placenta development: Murine adenosine deaminase as a model to study placenta specific expression, Bryan Marc Schaubach
Implication of bFGF signaling in lung carcinogenesis, Jie Shen
Importance of sperm transition proteins demonstrated in mice carrying Tnp1- and Tnp2-null alleles, Cynthia Renee Christian Shirley
Endogenous nitric oxide regulates p53 signaling and DNA damage-induced apoptosis in melanoma cells, Chi-Hui Tang
YKL -40, a vascular -associated serum marker for glioblastoma, correlates with chronic activation of AKT, Meena Kumari Tanwar
Loss of activator protein-2alpha results in overexpression of the thrombin receptor and correlates with the malignant phenotype of human melanoma, Carmen S Tellez
The roles of Smads and Pitx2 in cardiac development, Degang Wang
Functional studies of insulin-like growth factor binding protein 2 pathway in glioma progression, Hua Wang
Preclinical evaluation of proteasome inhibition for the treatment of prostate cancer, Simon Alexander Williams
Detecting the signature of natural selection with microsatellites, Hongyan Xu
Retinoic receptor gamma in squamous epithelial tumorigenesis, Hui Xu
Antitumor activity of an Ets protein, PEA3, in breast cancer cell lines MDA-MB-361DYT2 and BT474M1, Zhenming Yu
Submissions from 2002
Delineating the molecular basis of human genetic diseases: Epigenetic and functional studies, Dayna Tirpak Akey
Theoretical and experimental studies of linkage disequilibrium in human populations, Joshua Michael Akey
Role of FbpA and FbpB in the pathogenesis and mycolyltransferase activity of Mycobacterium tuberculosis, Lisa Yvonne Armitige
Characterization of the NOP -1 opsin photoreceptor in the filamentous fungus Neurospora crassa, Jennifer Anne Bieszke
Vasculogenesis: A process of vessel formation and its role during Ewing's sarcoma development, Marcela Fabiana Bolontrade de Fernandez
Regulation of Bcl-2 expression by the product of the prostate apoptosis response gene -4, Par-4, Sangeeta Kaur Cheema
Significance of tissue transglutaminase expression in multidrug resistant MCF -7 human breast cancer cells, Jack Shou-Kung Chen
Role of organic cation transporters in the renal secretion of nucleoside analogs, Rong Chen
Studies of the structure and function of a fibrinogen binding MSCRAMM(RTM) from Staphylococcus epidermidis, Stacey Lee Davis
Structural and functional analysis of p84N5, Randall Lowell Evans
Requirements for Staphylococcus aureus in vitro cellular internalization, Trent C Fowler
Isolation and characterization of a novel human Mix -like homeobox gene MIXL, Wei Guo
Activation of c -Met contributes to growth and metastasis of human colorectal carcinoma, Matthew H Herynk
Critical determinants of estrogen receptor -mediated agonist activity, Leslie Carol Hodges
Functional analysis of BMP4 signaling in mouse neural development, Qiyong Hu
Dimethylsphingosine evokes diverse cellular death modes in HL60, David Barqueti Jendiroba
RNA binding characteristics and overall topology of the vaccinia virus polyadenylation complex, Lela Ann Johnson
Functional analysis of the Galpha protein, GNA -3, in the development of Neurospora crassa using biochemical and genetic studies, Ann Marlena Kays
NFkappaB and STAT binding elements participate in regulation of MUC1 expression in normal and transformed mammary epithelial cells, Errin Leigh Lagow
Characterization of healing tissue in a tooth extraction socket in a rabbit model, Zahid Sultanali Lalani
Emodin, a tyrosine kinase inhibitor, and human cancer, Yiu-Keung (James) Lau
Characterization of hLodestar: A CDC5L interacting protein, Deana Marie Leonard
Genetic analysis of Pitx2 in left -right asymmetry and cardiovascular development, Chengyu Liu
The functions of pitx2 and Bmp signaling in craniofacial development, Wei Liu
Novel mechanisms for PKC family enzymes to regulate PI3K signaling pathway, Muling Mao
The role of endogenous IFN-beta in cutaneous melanoma: Consequences of epidermal hyperplasia, Marya Faith McCarty
Genetic integration of a nuclear -encoded mitochondrial gene with cardiac function, Meredith L Moore
4HPR-X radiation mechanisms of interactions in non-small cell lung cancer (NSCLC) cells in vitro, Melita Maria Nasca
The yeast STM1 protein binds G*G multiplex nucleic acids in vitro and associates with ribosomes in vivo, Laura Diane Nelson
The contributions of the hippocampal formation, perirhinal cortex and areas TH/TF to object, spatial and contextual recognition memory in primates, Sarah Ellen Nemanic
Calcium mobilization from the endoplasmic reticulum to the mitochondria during apoptosis in prostate cancer, Leta Kang Nutt
Analysis of BMP signalling through the receptor type IA in embryogenesis using conditional gene inactivation in mice, Dmitry Alexander Ovchinnikov
Alteration of CEACAM1 gene transcription in prostate cancer cells: The role of AR, Sp2, and HDAC, Dillon Thanh Phan
Cell survival in early embryogenesis requires proper dosage of GCN5 and p300, Huy Minh Phan
Plasmid -encoded virulence determinants of Borrelia burgdorferi, Joye Elizabeth Purser
*Ras proteins and human tumor cell radiosensitivity, Jeffery Scott Russell
The regulation of protein kinase C by thiol oxidation, Nancy Elaine Ward
Function and regulation of the Pem homeobox gene in vivo, Chad Michael Wayne
Requirement of the Jak2 tyrosine kinase in Bcr -Abl oncogenic transformation, Shanhai Xie
The heparan sulfate-fibroblast growth factor signaling system in liver growth and function, Chundong Yu
Identification and characterization of the vegetally localized Hermes mRNA, Nancy Ruth Zearfoss
Constitutively active cAMP receptor mutants dominantly inhibit receptor-mediated signaling pathways in Dictyostelium discoideum, Minghang Zhang
Adenosine mediated lung mast cell degranulation in the mouse, Hongyan Zhong
Submissions from 2001
Mapping and characterization of the Xlsirt P11 RNA cis-acting localization element, Luetta Ann Humphries Allen
An analysis of the function of region 1.2 of the primary sigma factor, sigma 70, from Escherichia coli, Nicole Elizabeth Baldwin
Role of janus tyrosine kinase -3 (JAK3) and signal transducer and activator of transcription (STAT5) pathway in T lymphocyte activation, Fariba Behbod
Cleavage and activation of calpain and its substrate caspase-7 in prostate cancer cells: Evidence for a role in apoptotic sensitization, Sharon Alexis Beresford
Positional candidate cloning of the RP10 form of retinitis pigmentosa, Sara Juanita Bowne
Pencil -beam redefinition algorithm dose calculations for electron therapy treatment planning, Robert Arthur Boyd
Cross -packing among retroviruses and characterization of the feline immunodeficiency virus (FIV) packaging signal: Implications for the development of FIV-based gene transfer systems, Matthew Taylor Browning
Temporal analysis of PI-3kinase and MAPK signal transduction during skeletal muscle overload, Christian Joseph Carlson
Integrin mediated growth and apoptosis in human gastric adenocarcinoma, Denise Anne Caruso
A novel myeloid leukemia suppressor locus at human chromosome 5q13.3, Patricia Diane Castro
Mechanisms of Ad-p53 induced apoptosis in human malignant glioma, Julie Ann Marie Cerrato
Mechanisms of TGF-beta1-induced neuronal plasticity in Aplysia, Jeannie Chin
Participation of bcl -2 and bax in epidermal homeostasis and non-melanoma skin cancer, Song Hye Cho
Genetic alterations associated with prostate cancer progression, Lisa Wey-Lan Chu
The functional role of the tumor suppressor MMAC /PTEN in glioblastoma multiforme and prostate cancer, Michael Arwyn Davies
Mechanisms of apoptosis in bleomycin-induced lung injury: Implications for pulmonary fibrosis, Darren Wynn Davis
Functional activation of p53 induces apoptosis in the absence of MDM2, Sohela de Rozieres
Signal transduction of CEACAM1-L tumor suppressor, Vicky Sharon Tantingco Estrera
Fas ligand and soluble Fas -opposing molecules in melanoma lung metastasis, Christopher Louis Hall
Estradiol and insulin cross -talk in breast cancer, Ginny Graham Hutchins
Regulation of p53 antiproliferative function by transactivation domain phosphorylation at threonine 18 and serine 20, James Ramzi Jabbur
Collagen I modulates growth and gene expression in prostate cancer cells, Jeffrey Allen Kiefer
Development of colorectal cancer gene therapy, Ka Yin (Simon) Kwong
Impact of BCR -ABL on DNA repair, Eunice Laurent
Molecular regulatory mechanisms and embryonic tissue specification in sea urchin development, Xiaotao Li
From gene to protein: Investigating the disease etiology of retinitis pigmentosa, Kimberly Anne Malone
Functional and physical associations of beta1 integrins in the activation of human T lymphocytes, Yuko June Miyamoto
Familial aggregation, candidate genes and genome scans: Analyzing the role of genetics in stroke, Alanna Christine Morrison
Human complement component C3 -binding proteins of Mycobacterium tuberculosis, Stacey Leigh Mueller-Ortiz
Predictors of benzodiazepine self -administration behavior in anxious patients, Lynn Marie Miklas Oswald
Molecular mechanisms of apoptosis induction in chronic lymphocytic leukemia, Jessica Caroline Pahler
Rescue of embryonic lethality in mdmx null mice by loss of p53 suggests a non-overlapping pathway with MDM2 to regulate p53, John Michael Parant
Learning -dependent plasticity of movement representations in the primate primary motor cortex, Erik Jon Plautz
The role of LMX1B and PITX2 in anterior segment development and adult ocular function, Carolyn Leah Pressman