Digital dissertations from 1966-2009. Free access is limited to The TMC Library's academic-level users; other users may be able to obtain them through their own libraries or purchase them from ProQuest. For remote access click here.

Dissertations from 2009-the present are open-access here in DigitalCommons@TMC.

Older UT GSBS dissertations (dating approximately 1979-1999) are available at The TMC Library in print format. Check the Library Catalog. For best results, search using the subject heading: "Dissertations, Academic--University of Texas Health Science Center at Houston. Graduate School of Biomedical Sciences."

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Submissions from 2001

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Arabinosylguanine: Metabolism, action, and lineage-specific cytotoxicity in human leukemia cells, Carlos O. Rodriguez

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A study in the molecular and cellular functions of GSK3beta in prostate adenocarcinoma, Thomas Ricardo Salas

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Dielectrophoretic approaches to sample preparation and analysis, Jon Alexander Schwartz

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Regulation of vascular endothelial growth factor expression in human pancreatic cancer, Qian Shi

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Circumvention of cellular defense responses to DNA -directed nucleoside analogues by the protein kinase inhibitor, UCN-01, Zheng (Jane) Shi

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Characterization of template switching and recombination during Moloney murine leukemia virus replication, Cynthia Ruth Skinner

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Fast magnetic resonance temperature imaging for focused ultrasound thermal therapy, Roger Jason Stafford

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Learning in the cerebellar nucleus is necessary for acquisition of Pavlovian eyelid conditioning, Philip Michael Steele

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Temporal and spatial regulation of cell division by the nucleoid in Escherichia coli, Qin Sun

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Identification and characterization of antigens and potential virulence factors in Enterococcus, Fang Teng

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Role of cytochrome P450 in DNA damage produced by treatment of colon cells with 1,2-dimethylhydrazine, Hernan G Vasquez-Jaramillo

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Evaluation of candidate genes for susceptibility to spina bifida, Kelly Ann Volcik

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Dielectrophoresis-based analyte separation and analysis, Jody Valentine Vykoukal

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An interferon-inducible protein, p202, in cancer gene therapy, Yong Wen

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Physical and functional mapping of a novel tumor suppressor locus for prostate cancer within chromosome 10p12.31-q11, Patricia Eva Wong

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PML tumor suppressor potentiates cell death through inhibition of the NF -kappa B survival pathway, Wen-Shu Wu

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The utility of N5 for gene therapy of human cancer, Shenmin Yin

Submissions from 2000

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Glucocorticoid alterations in the human type-1/type-2 cytokine balance and the role of CD28/B7 costimulation, Sandeep Krishna Agarwal

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Tumor immunization strategies for enhancing the graft versus tumor activity of allogeneic bone marrow transplantation, Larry Don Anderson

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Constitutive expression of interleukin-6 in renal cell carcinoma is modulated by p53, Laura Searfoss Angelo

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Expression cloning of a candidate prostate cancer oncogene, Jimmy Jarald Caudell

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Modulation of replicative senescence of skeletal muscle satellite cells by insulin -like growth factor-I (IGF-I), Manu V Chakravarthy

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Functional studies of a LIM -homeodomain transcription factor lmx1b in murine mid -hindbrain and limb development, Haixu Chen

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Retinoid -induced regression of human head and neck squamous cell carcinomas is associated with the induction of a pro -inflammatory response, Mimi Cho

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A novel mechanism of regulation of phosphatidylinositol 3 -kinase: Tyrosine phosphorylation of p85 residue 688, Bruce Daniel Cuevas

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Regulation of sex hormone dependent growth by a serum borne inhibitor, Jorge E. Moreno Cuevas

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Cytochrome P450 4F isoforms in different species: Identification, gene regulation and putative roles in inflammation, Xiaoming Cui

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Proteolytic mechanisms of cell injury following glucose -oxygen deprivation in primary neuronal cultures, Jennifer Kiersten Newcomb Fernandez

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Is sensitization to stimulants time dependent and mediated via NMDA receptors?, Osvaldo Gaytan

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Regulations of SOX9 activity during chondrogenesis, Wendong Huang

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The role of p53 in skin cancer induction by UV radiation and as a potential tumor antigen in UV-induced murine skin tumors, Weidong Jiang

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The antiapoptotic effect of overexpression c -erBb2 in breast cancer, Tong Jing

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Enhanced in vivo angiogenesis within a model tissue engineered construct using biodegradable microspheres containing encapsulated VEGF, Timothy Wells King

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Axl -Gas6 signaling counteracts adenovirus type 5 E1A-mediated cell growth suppression and proapoptotic activity, Wei-Ping Lee

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Characterization of anti -sulfatide autoantibodies in demyelinating diseases, Bin Liu

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Genetic and functional analyses of cell division proteins FtsZ and FtsA in Escherichia coli, Xiaolan Ma

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A novel treatment planning methodology for high dose 166Ho-DOTMP therapy in patients with multiple myeloma, Steven Patrick McCullough

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Cerebellar mechanisms for motor learning: Testing predictions from a large-scale computer simulation, Javier Francisco Medina

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Identification and characterization of cellular genes differentially expressed in a subset of tumors with non -functional WT1, Hariyadarshi Pannu

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Identification and characterization of virulence factors in Enterococcus faecalis, Xiang Qin

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Dual role of interleukin-12 on ultraviolet -induced immune suppression, David Alan Schmitt

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Genome -wide and locus -specific instability, Salina Victoria Spring

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The localization and identification of candidate tumor suppressor genes involved in prostate cancer, Jonathan Daemon Stein

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Variables affecting the stability of multiple cloning sites and hairpin structures in retroviral vectors, John Renn Su

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Searching for the ideal DNA recognition code of covalent ligands, Gulshan Fram Sunavala

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The role of erbB2 receptor in human breast cancer metastasis, Ming Tan

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Characterization of recombinant class I MHC alloantigen action upon the survival of disparate heart allografts, Barton Wink Trawick

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Functional requirements of histone deacetylases in Tup1-Ssn6 repression, Anjanette Dee Watson

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Ovarian cancer angiogenesis, biology and therapy, Lei Xu

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Biochemical and genetic analysis of two protein kinases JNKK2 and MEKK3, Jianhua Yang

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Activation of matrix metalloproteinase -9 (MMP-9) by heregulin in human breast cancer cells involves multiple signaling pathways, Jun Yao

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The role of MAPK during the activation of NK cells, Tse-Kuan Yu

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Structural conservations and diversities of dsRNA viruses: Structural studies of the cytoplasmic polyhedrosis virus by electron cryomicroscopy and 3D reconstruction, Hong Zhang

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Global patterns of DNA polymorphism in noncoding regions in human populations, Zhongming Zhao

Submissions from 1999

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A urokinase receptor promoter element (-152/-135) bound with an AP-2-alpha-related protein and SP1 is required for the induction of gene expression by PMA and SRC, Heike Allgayer

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In vivo definition of genetic and cellular aspects of mammalian sexual differentiation, Nelson Alexander Arango

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Effects of butyrate on the colon cancer cell phenotype-chemosensitization and upregulation of proteins implicated in cancer progression, Philip John Bergman

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Transcription factor SEF: Purification and functional characterization, Zhanyong Bing

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Functional analysis of SOX9 in chondrogenesis by targeted gene inactivation, Weimin Bi

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Behavioral effects of plasma tryptophan depletion in aggressive and nonaggressive men, James Matthew Bjork

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The two -state model of receptor activation: The agonist and the efficacy, Tracy Lynn Blevins

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The LPS O -antigen is required for Myxococcus xanthus social motility and multicellular development, Maria Gabriela Bowden

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The role of conserved region 1 of Escherichia coli sigma-70 in transcription initiation, Christina Wilson Bowers

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Immunology and HIV expression in skin, in vitro, and in response to ultraviolet light, Joan Nancy Breuer-McHam

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The role of menaquinone in the nitrate reductase complex, Francisco R Brito

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Potential roles for bcl-2 in the pathogenesis, progression, and treatment of prostate cancer, Elizabeth Mary Bruckheimer

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Purification and cloning of the novel phosphoprotein copine III and characterization of its associated kinase activity, Eva Gisela Caudell

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Transcriptional regulation of the human Fas (CD95) promoter, Henry Him Lei Chan

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Analysis of Lim1 LIM domains in mouse development, Siew-Sim Cheah

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Transcriptional regulation of cell lineage-specific expression of the murine type I collagen genes and of osteoblast differentiation, Su Sin Chen

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Structural studies of cytochrome P4501A1: Identification of substrate and cumene hydroperoxide binding regions in the active site of P4501A1 and characterization of the P4501A1 interaction with cytochrome P450 reductase, Tomas Cvrk

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A distinct element involved in the lipopolysaccharide activation of the tumor necrosis factor -alpha promoter in a promonocytic cell line, THP-1, Belisa Diaz

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Estrogen action during early mouse mammary gland development, Donna DiPaolo

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Regulation of phosphatidylinositide turnover in the myometrium by cAMP: Implications for the control of uterine contraction, Kimberly Lynn Dodge

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Diffusion tensor imaging of rat spinal cord in vivo, David Anthony Fenyes

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A study of the biology of perlecan, Margaret McIntosh French

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The effect of protein tyrosine phosphatase SHP1 on tumorigenicity of the MDA -MB231 breast cancer cells, Chuan Gao

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Analysis of primary Wilms tumors for WT1 RNA processing alterations, Kerry Bryce Gunning

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ATXA -dependent gene expression in Bacillus anthracis, Alex R Hoffmaster

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The cDNA cloning of murine HIP /L29 and the functional analysis of HIP/L29 domains, David Edmund Hoke

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Functional analysis of GNA -1, a Galphai superfamily member found in the filamentous fungus Neurospora crassa, Frank Douglas Ivey

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The role of the amino terminus of Bacillus subtilis sigmaK in transcription initiation, Bradley Dan Johnson

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Protein-protein interaction between phototaxis receptor sensory Rhodopsin I and its transducer HtrI, Kwang-Hwan Jung

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NMR structural analysis of cardiac troponin C: Monitoring conformational changes induced by binding calcium, troponin I, and calcium -sensitizing drugs, Quinn Koos Kleerekoper

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Behavioral and cellular analysis of classical conditioning of feeding behavior in Aplysia, Hilde Anna Elisabeth Lechner

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The cGMP -PKG pathway is critical for inducing long-term sensitization of identified nociceptive sensory neurons, Matthew Robert Lewin

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Signals underlying the induction and expression of long-term, injury-related plasticity in sensory neurons of Aplysia, Xiaogang Liao

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The Shc adaptor protein and its role on Her -2 /neu oncogenesis, Kaiyi Li

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Two prognostic factors in breast cancer: Novel functions of EGFR and beta-catenin, Shiaw-Yih Lin

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Altered tumorigenic phenotype in mice with a hypomorphic p53 mutant allele, Geng Liu

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Rapid effects of 1alpha,25-dihydroxyvitamin D3 on osteoblasts: Studies of membrane transducers that affect calcium signals, Riting (Allan) Liu

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The effects of IL -10 producing monocytes on T-cell activation in patients with epithelial ovarian cancer, Amy Elizabeth Loercher

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Developmental effects of estrogen and PCBs in the reproductive tract of BALB/C mice, Jeanelle M Martinez

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Delineation of a novel genetic region at 5q11 harboring tumor suppressor gene(s) and identification of the telomeric DNA as a marker for human prostate cancer, Mustafa Ozen

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Development of a protective vaccine against Helicobacter pylori, Bulent Ozpolat

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The mechanism of the pharmacological actions of dexrazoxane on different tissue types, Michael Leslie Pearlman

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Role of transducer proteins in photoaxis signaling of Halobacterium salinarum, Bastianella Perazzona

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Tolerance of allografts across MHC barriers by allochimeric class I MHC proteins, Johnny Perez

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Structural studies of proteinase entrapment by human alpha 2-macroglobulin using 3-D electron microscopy, Usman Abdul Aziz Qazi

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Population and molecular evolution studies on the Melanocortin 1 receptor locus implicate its role in human pigmentation variation, Brinda Kawti Rana