Digital dissertations from 1966-2009. Free access is limited to The TMC Library's academic-level users; other users may be able to obtain them through their own libraries or purchase them from ProQuest. For remote access click here.

Dissertations from 2009-the present are open-access here in DigitalCommons@TMC.

Older UT GSBS dissertations (dating approximately 1979-1999) are available at The TMC Library in print format. Check the Library Catalog. For best results, search using the subject heading: "Dissertations, Academic--University of Texas Health Science Center at Houston. Graduate School of Biomedical Sciences."

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Submissions from 1999

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Transcriptional repression of serum amyloid A1 by AP -2 contributes to its liver -specific expression, Yongsheng Ren

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New algorithms for automated phylogenetic reconstruction using artificial intelligence and data mining techniques, Andrew S Rodin

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Characterization of osteopontin charge forms produced by osteoblasts, Jeffrey Bryan Safran

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Identification and evaluation of candidate genes for inherited retinal -degenerative diseases, Melanie Michelle Sohocki

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Effects of exogeneous p53 on growth suppression, apoptosis, and differentiation in oral cancer cell lines, Lisa Susanne St. John

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Cytochrome P450 2D18 in the mammalian brain: Recombinant expression, purification, and characterization of xenobiotic and endobiotic metabolism, Chadwick Moore Thompson

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New implications of E1A gene therapy in breast and ovarian cancer, Naoto Tada Ueno

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Use of a hypomorphic allele of myogenin to analyze Myogenin-dependent processes in mouse development, Jay LaVerne Vivian

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A novel form of CYP3A from rat brain: cDNA cloning, protein characterization and gene regulation of cytochrome P450 3A9, Huamin Wang

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A novel DNA damage inducible inhibitor of p53, Sung-Ling Wang

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Bcr: A conditional inhibitor of Bcr -Abl oncoprotein, Yun Wu

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Modular organization of the cortical connections linking visual areas V1, V2 and V4 in Macaque monkeys, Youping Xiao

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Mechanism of mRNA stability control mediated by AU -rich element: Characterization of cis-elements and trans-factors, Nianhua Xu

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Functions of GCN5 and P /CAF acetyltransferases in mammalian development, Wanting Xu

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Heterotrimeric G protein -mediated signal transduction in Neurospora crassa, Qi Yang

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Interactions and structural analysis of the zinc -binding motif in decorin, a small leucine rich proteoglycan in extracellular matrix, Vivian Wei-Chung Yang

Submissions from 1998

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The role of specific regions of ribosomal RNAs in translation termination, Alexey Leonovich Arkov

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Growth regulatory role of R -PTPmu in normal and neoplastic epithelial cells, Pedro Jose Beltran

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Regulation of angiogenesis by interferon-beta, Diane Renee Bielenberg

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Linkage and association of candidate obesity genes in Mexican-Americans from Starr County, Texas, Molly Sue Bray

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Autoregulation of TRA-2 pre -mRNA splicing, Dawn Suzan Chandler

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Mechanisms of apoptosis in chronic lymphocytic leukemia (CLL), Joya Chandra

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Identification and characterization of genes encoding phospholipid biosynthetic enzymes of {\it Saccharomyces cerevisiae\/}, Shao-Chun Chang

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Study of retinoic acid signaling in cancer cells: Cloning and characterization of retinoic acid responsive genes, Yijun Cheng

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Stability and potential application of spliced nuclear pre -mRNA introns, Jade Qiuyu Clement

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Suppression of T lymphocyte activation in simulated microgravity, David Cooper

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Analysis of VirB4, a membrane-associated ATPase subunit essential for T -complex transport in Agrobacterium tumefaciens, Tu Anh Tran Dang

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Characterization of dermatan sulfate proteoglycan 3 (DSPG3) and cartilage oligomeric matrix protein (COMP), Michelle Williams Deere

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Mechanisms of adenovirus 5 E1A -mediated tumor suppression and E1A-mediated apoptosis, Jiong Deng

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Redistribution of plasma membrane phosphatidylserine during erythroid development, Cecilia Diaz-Oreiro

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Effects of galectin-1 and galectin-3 expression on prostate cancer cell adhesion, differentiation, proliferation, and tumorigenicity, Julie Ann Ellerhorst

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Characterization of the interactions between two sites of plasticity engaged during eyelid conditioning, Keith Siamond Garcia

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Cloning and genetic characterization of Skb1: A novel regulator of Shk1 and mitosis in Schizosaccharomyces pombe, Mary Alice Gilbreth

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Expression of neuromuscular junction messenger RNAs and protein in aged rats, Ronald Richard Gomes

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Modulating bioreductive drug activity with antivascular agents, Virginia Lynn Harrod

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Inputs to parasol ganglion cells in the primate retina, Roy Alton Jacoby

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Structural determinants of subunit -subunit interactions and subcellular localization of the calcium /calmodulin -dependent protein kinase II, Stephen James Kolb

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Development of prostate cancer gene therapy, Song-Chu Ko

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Peptide nucleic acids: Mechanism of tight binding and application in artificial nuclease, Larisa Anatolievna Kosynkina

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Analysis of the mechanism of replication inhibition of the tumor suppressor gene p53, Eliyahu Kraus

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Esx1 is an X-chromosome-imprinted regulator of placental formation and fetal growth, Yuanhao Li

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Cost and power analysis of linkage disequilibrium methods for locating genes influencing quantitative traits in humans, Grier Philip Page

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Studies of subcellular localization and complex formation of the Agrobacterium tumefaciens transport ATPase VirB11, Svetlana Lazarova Rashkova

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Modulation of BCL-X$\sb{\rm L}$ is a critical determinant of c-myc induced apoptosis, Mona Sarkiss

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Investigation of mechanisms involved in ultraviolet B radiation-induced, T cell -mediated immune suppression, Vijay Krishnarathnam Shreedhar

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Aberrant regulation of the Src -FAK signaling pathway in the human colon adenocarcinoma cell line HT-29, Doris Rieko Siwak

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The evolution of paired domains, Hongmin Sun

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A genetically engineered, adherent smooth muscle cell lining for left ventricular assist devices, Christine Linn Tock

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myogenin: Human candidate gene and knockout mouse effect, Brian Siang-Juh Tseng

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The role of BCL-2 in regulation of apoptosis susceptibility by modulation of glutathione, David Ward Voehringer

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Integrins in human T cell function: Transdominant regulation, conformational constraints, and intracellular effectors, Darren G Woodside

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Integrin signaling in the regulation of lymphocyte morphology, David Kent Wooten

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Mechanism of molecular regulation of nuclear -encoded mitochondrial gene expression by electrical stimulation in the cultured neonatal rat cardiac myocytes, Yang Xia

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Biological effects of PEA3 expression in {\it HER-2\/}/{\it neu\/}-overexpressing human cancer cells and the molecular mechanisms of PEA3-mediated transcriptional repression on {\it HER-2\/}/{\it neu\/}, Xiangming Xing

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Molecular and genetic analysis of Myxococcus xanthus early *development, Di Xu

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Involvement of a region of 23S ribosomal RNA of {\it E. coli\/} in decoding of termination codons, WenBing Xu

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Identification of antigen-encoding genes of Enterococcus faecalis during human infections and characterization of a gene cluster for the biosynthesis of an antigenic polysaccharide, Yi Xu

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The SasS -SasR two-component signal transduction system required for early Myxococcus xanthus multicellular *development, Chun Yang

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Development of combined micro -preparation, separation, and mass spectrometry methods and application in the microdialysis study of neuropeptide metabolism, Haiying Zhang

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Functional analysis of histones H3 and H4 in Tup1 repression and in GCN5 activation, Wenzheng Zhang

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Transcriptional regulation and functional analysis of the human Wilms' tumor 1 gene, Xiaohong Zhang

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Phototaxis signaling by the membrane complex of archaeal sensory rhodopsins and their transducers, Xue-Nong Zhang

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Functions and intramolecular interactions of ribosomal RNA in decoding of termination codons, Song Qing Zhao

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Transcriptional regulation of the rat {\it mdr1b\/} gene, Ge Zhou

Submissions from 1997

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Genetic predisposition to prostate cancer, Michael D Badzioch

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Genes to blood pressure: The effects of variation in genes of the renin-angiotensin system on the hormonal and renal control of blood pressure, Alan Lee Biddinger

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Radiolabeled human monoclonal IgM for intracompartmental cancer therapy, Paul Eric Borchardt

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Targeting of {\it HER\/}-{\it 2\/}/{\it neu\/} with E1A gene therapy, Joe Yujiao Chang

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Regulatory factors and control of anthrax toxin gene expression, Zhihao Dai

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Osteopontin (OPN) and neoplastic disease: Circulating levels and tissue distribution, Robert Earl Devoll

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drp, A novel cell density regulated protein, Jeffrey E Deyo

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Regulation of the expression of {\it mutS, mutL}, and {\it mutH\/} mismatch repair genes in {\it Escherichia coli\/} K-12, Gang Feng

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Identification of the signal pathways modulated by expression of p210$\rm\sp{bcr-abl}$ and the inhibition of p210$\rm\sp{bcr-abl}$ transforming activity by polypeptides interacting with p210$\rm\sp{bcr-abl}$ in murine myeloid 32D cells, Xiang-Yang Guo

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Mouse models and quantitative trait loci of susceptibility to bleomycin- and radiation-induced pulmonary fibrosis, Christina Kathleen Haston

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Role and regulation of c-KIT gene expression in tumor growth and metastasis of human melanoma, Suyun Huang

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Inactivation and self -association of CaM kinase: Effects of ATP, substrate binding domains, and isozymic forms, Andy Hudmon

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Mechanism of silica -induced apoptosis in human alveolar macrophages, Rashi Iyer

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$\beta\sb2$-adrenergic receptor desensitization, internalization and phosphorylation in response to full and partial agonists, Bridgette Goodwin January

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Design, synthesis and biological evaluation of 5$\sp\prime$-mononucleotide prodrugs: Strategies to introduce nucleotides into cells, Saeed R Khan

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2-methylthio-N$\sp6$-dimethylallyl modification of adenosine 37 of tRNAs in {\it Escherichia coli\/} K-12, Hon-chiu Eastwood Leung

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Evidence for the involvement of proximal chromosome 3P loci in the progression of Von Hippel-Lindau related tumors, Steven Trent Lott

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Regulation of pyridoxal $5\prime$-phosphate biosynthesis in {\it Escherichia coli\/} K-12, Tsz-Kwong Man

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Involvement of {\it p53\/} in PUVA-induced skin cancers, Arun Jayaraman Nataraj

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Fibrillins: Sequence, phylogeny and carboxy terminal domain proteolytic processing, Timothy Mark Ritty

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Functional studies of the homeobox gene {\it Goosecoid\/} during mouse embryogenesis, Jaime Antonio Rivera-Perez

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Regulation of apoptosis during the pathogenesis of non -melanoma skin cancer, Julio Garcia Rodriguez-Villanueva

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Role of {\it ERCC1\/} in DNA repair and genetic recombination, Rhonda Lynn Rolig

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Regulation of phospholipid biosynthesis in {\it Saccharomyces cerevisiae\/} by CDP-diacylglycerol synthase, Haifa Shen

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The volume effect in irradiated mouse colorectum, Mark William Skwarchuk

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Genetic analysis of tumor progression susceptibility in the mouse skin model, Mariana Carla Stern

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Structure-function analyses of {\it PAX6\/} and the molecular bases of aniridia, Hank Kejun Tang

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The identification and regulation of a novel interaction occurring between $\beta$-catenin and the actin -bundling protein fascin, Ying-Shuang Tao

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Accessing novel developmental mechanisms in the mouse by gene trapping, Daniel Scudder Wagner

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Rescue from apoptosis in early (CD34 selected) versus late (CD34 unselected) human hematopoietic cells by VLA-4 and VCAM-1 dependent adhesion to bone marrow stromal cells, Wen-jung Michael Wang

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Transcriptional regulation of the human {\it PAX6\/} gene, Zheng-Ping Xu

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Long-term synaptic facilitation of tail sensorimotor connections in {\it Aplysia\/}, Fan Zhang

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Antigenic variation in Lyme disease spirochetes by segmental recombination of VMP-like sequence cassettes, Jing-Ren Zhang

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Molecular mechanisms of chondrocyte-specific expression on the mouse pro$\alpha$1(II) collagen gene, Guang Zhou

Submissions from 1996

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Aggression, impulsivity and serotonin in drug dependence, Terry Jean Allen

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{\it RAS\/} is required for the expression of interleukin-1$\beta$ in two diverse leukemic cell lines, Darrin M Beaupre