Open-access journal articles from UT GSBS faculty and students.
Submissions from 2010
S9511: a Southwest Oncology Group phase II study of trimetrexate, 5-fluorouracil, and leucovorin in unresectable or metastatic adenocarcinoma of the stomach., Charles D Blanke, Kari Chansky, Kathy L Christman, Scott A Hundahl, Brian F Issell, Peter J Van Veldhuizen, G Thomas Budd, James L Abbruzzese, and John S Macdonald
FoxM1B regulates NEDD4-1 expression, leading to cellular transformation and full malignant phenotype in immortalized human astrocytes., Bingbing Dai, Russell O Pieper, Dawei Li, Ping Wei, Mingguang Liu, Shiao Y Woo, Kenneth D Aldape, Raymond Sawaya, Keping Xie, and Suyun Huang
Evolutionary conservation of residues in vertebrate DNA polymerase N conferring low fidelity and bypass activity., Kei-ichi Takata, Mercedes E Arana, Mineaki Seki, Thomas A Kunkel, and Richard D Wood
Loss of DNA polymerase zeta enhances spontaneous tumorigenesis., John P Wittschieben, Vaishali Patil, Veronika Glushets, Lisa J Robinson, Donna F Kusewitt, and Richard D Wood
Polymorphisms of the DNA repair gene MGMT and risk and progression of head and neck cancer., Zhengdong Zhang, Luo Wang, Sheng Wei, Zhensheng Liu, Li-E Wang, Erich M Sturgis, and Qingyi Wei
Submissions from 2009
CA125/MUC16 is dispensable for mouse development and reproduction., Dong-Joo Cheon, Ying Wang, Jian Min Deng, Zhen Lu, Lianchun Xiao, Chun-Ming Chen, Robert C Bast, and Richard R Behringer
CREB mediates prostaglandin F2alpha-induced MUC5AC overexpression., Wen-Cheng Chung, Seung-Hee Ryu, Hongxia Sun, Darryl C Zeldin, and Ja Seok Koo
Dicer is required for female reproductive tract development and fertility in the mouse., Gabriel Gonzalez and Richard R Behringer
Long-term survival after multidisciplinary management of resected pancreatic adenocarcinoma., Matthew H G Katz, Huamin Wang, Jason B Fleming, Charlotte C Sun, Rosa F Hwang, Robert A Wolff, Gauri Varadhachary, James L Abbruzzese, Christopher H Crane, Sunil Krishnan, Jean-Nicolas Vauthey, Eddie K Abdalla, Jeffrey E Lee, Peter W T Pisters, and Douglas B Evans
KEAP1 E3 ligase-mediated downregulation of NF-kappaB signaling by targeting IKKbeta., Dung-Fang Lee, Hsu-Ping Kuo, Mo Liu, Chao-Kai Chou, Weiya Xia, Yi Du, Jia Shen, Chun-Te Chen, Longfei Huo, Ming-Chuan Hsu, Chia-Wei Li, Qingqing Ding, Tsai-Lien Liao, Chien-Chen Lai, Ann-Chi Lin, Ya-Hui Chang, Shih-Feng Tsai, Long-Yuan Li, and Mien-Chie Hung
Therapeutic Targeting of ATP7B in Ovarian Carcinoma., Lingegowda S Mangala, Vesna Zuzel, Rosemarie Schmandt, Erik S Leshane, Jyotsna B Halder, Guillermo N Armaiz-Pena, Whitney A Spannuth, Takemi Tanaka, Mian M K Shahzad, Yvonne G Lin, Alpa M Nick, Christopher G Danes, Jeong-Won Lee, Nicholas B Jennings, Pablo E Vivas-Mejia, Judith K Wolf, Robert L Coleman, Zahid H Siddik, Gabriel Lopez-Berestein, Svetlana Lutsenko, and Anil K Sood
Antibodies targeting hepatoma-derived growth factor as a novel strategy in treating lung cancer., Hening Ren, Zuoming Chu, and Li Mao
Submissions from 2008
An Sp1/Sp3 binding polymorphism confers methylation protection., Yanis A. Boumber, Yutaka Kondo, Xuqi Chen, Lanlan Shen, Yi Guo, Carmen Tellez, Marcos R H Estécio, Saira Ahmed, and Jean-Pierre J. Issa
Killing of human melanoma cells induced by activation of class I interferon-regulated signaling pathways via MDA-7/IL-24., Suhendan Ekmekcioglu, John B Mumm, Malini Udtha, Sunil Chada, and Elizabeth A Grimm
Sp1 up-regulates cAMP-response-element-binding protein expression during retinoic acid-induced mucous differentiation of normal human bronchial epithelial cells., Jeong Soo Hong, Seung-Wook Kim, and Ja Seok Koo
Eomesodermin, a target gene of Pou4f2, is required for retinal ganglion cell and optic nerve development in the mouse., Chai-An Mao, Takae Kiyama, Ping Pan, Yasuhide Furuta, Anna-Katerina Hadjantonakis, and William H Klein
LY2109761, a novel transforming growth factor beta receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis., Davide Melisi, Satoshi Ishiyama, Guido M Sclabas, Jason B Fleming, Qianghua Xia, Giampaolo Tortora, James L Abbruzzese, and Paul J Chiao
Genetic variation in genes for the xenobiotic-metabolizing enzymes CYP1A1, EPHX1, GSTM1, GSTT1, and GSTP1 and susceptibility to colorectal cancer in Lynch syndrome., Mala Pande, Christopher I Amos, Daniel R Osterwisch, Jinyun Chen, Patrick M Lynch, Russell Broaddus, and Marsha L Frazier
REST maintains self-renewal and pluripotency of embryonic stem cells., Sanjay K Singh, Mohamedi N Kagalwala, Jan Parker-Thornburg, Henry Adams, and Sadhan Majumder
FoxM1B transcriptionally regulates vascular endothelial growth factor expression and promotes the angiogenesis and growth of glioma cells., Yujian Zhang, Nu Zhang, Bingbing Dai, Mingguang Liu, Raymond Sawaya, Keping Xie, and Suyun Huang
Submissions from 2007
Phosphorylation of the proline-rich domain of Xp95 modulates Xp95 interaction with partner proteins., Robert E Dejournett, Ryuji Kobayashi, Shujuan Pan, Chuanfen Wu, Laurence D Etkin, Richard B Clark, Oliver Bögler, and Jian Kuang
Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia., Benjamin T Kile, Athanasia D Panopoulos, Roslynn A Stirzaker, Douglas F Hacking, Lubna H Tahtamouni, Tracy A Willson, Lisa A Mielke, Katya J Henley, Jian-Guo Zhang, Ian P Wicks, William S Stevenson, Paquita Nurden, Stephanie S Watowich, and Monica J Justice
Regulation of mucin gene expression by CREB via a nonclassical retinoic acid signaling pathway., Seung-Wook Kim, Jeong Soo Hong, Seung-Hee Ryu, Wen-Cheng Chung, Joo-Heon Yoon, and Ja Seok Koo
Is a 3-mm intrafractional margin sufficient for daily image-guided intensity-modulated radiation therapy of prostate cancer?, Adam D Melancon, Jennifer C O'Daniel, Lifei Zhang, Rajat J Kudchadker, Deborah A Kuban, Andrew K Lee, Rex M Cheung, Renaud de Crevoisier, Susan L Tucker, Wayne D Newhauser, Radhe Mohan, and Lei Dong
K1 protein of human herpesvirus 8 suppresses lymphoma cell Fas-mediated apoptosis., Suizhao Wang, Shu Wang, Hoyoung Maeng, Daniel P Young, Om Prakash, Luis E Fayad, Anas Younes, and Felipe Samaniego
Single-stranded DNA-binding proteins regulate the abundance of LIM domain and LIM domain-binding proteins., Zhixiong Xu, Xianzhang Meng, Ying Cai, Hong Liang, Lalitha Nagarajan, and Stephen J Brandt
Submissions from 2006
Constitutive NF-kappaB and NFAT activation leads to stimulation of the BLyS survival pathway in aggressive B-cell lymphomas., Lingchen Fu, Yen-Chiu Lin-Lee, Lan V Pham, Archito Tamayo, Linda Yoshimura, and Richard J Ford
Natriuretic peptides and nitric oxide stimulate cGMP synthesis in different cellular compartments., Leslie A Piggott, Kathryn A Hassell, Zuzana Berkova, Andrew P Morris, Michael Silberbach, and Thomas C Rich
Abnormal expression of REST/NRSF and Myc in neural stem/progenitor cells causes cerebellar tumors by blocking neuronal differentiation., Xiaohua Su, Vidya Gopalakrishnan, Duncan Stearns, Kenneth Aldape, Fredrick F Lang, Gregory Fuller, Evan Snyder, Charles G Eberhart, and Sadhan Majumder
Platelet-activating factor is crucial in psoralen and ultraviolet A-induced immune suppression, inflammation, and apoptosis., Peter Wolf, Dat X Nghiem, Jeffrey P Walterscheid, Scott Byrne, Yumi Matsumura, Yasuhiro Matsumura, Cora Bucana, Honnavara N Ananthaswamy, and Stephen E Ullrich
Submissions from 2005
Activation of Src kinase Lyn by the Kaposi sarcoma-associated herpesvirus K1 protein: implications for lymphomagenesis., Om Prakash, O Rama Swamy, Xiochang Peng, Zhen-Ya Tang, Li Li, Janet E Larson, J Craig Cohen, Javed Gill, Gist Farr, Suizhao Wang, and Felipe Samaniego
Prime-boost vaccination with plasmid and adenovirus gene vaccines control HER2/neu+ metastatic breast cancer in mice., Xiaoyan Wang, Jian-Ping Wang, Xiao-Mei Rao, Janet E Price, Heshan S Zhou, and Lawrence B Lachman
Submissions from 2004
NF-kappaB and AP-1 connection: mechanism of NF-kappaB-dependent regulation of AP-1 activity., Shuichi Fujioka, Jiangong Niu, Christian Schmidt, Guido M Sclabas, Bailu Peng, Tadashi Uwagawa, Zhongkui Li, Douglas B Evans, James L Abbruzzese, and Paul J Chiao
Conversion of myoblasts to physiologically active neuronal phenotype., Yumi Watanabe, Sei Kameoka, Vidya Gopalakrishnan, Kenneth D Aldape, Zhizhong Z Pan, Frederick F Lang, and Sadhan Majumder
The recombinant adeno-associated virus vector (rAAV2)-mediated apolipoprotein B mRNA-specific hammerhead ribozyme: a self-complementary AAV2 vector improves the gene expression., Shumei Zhong, Shihua Sun, and Ba-Bie Teng
Submissions from 2003
rIFN-gamma-mediated growth suppression of platinum-sensitive and -resistant ovarian tumor cell lines not dependent upon arginase inhibition., Bohuslav Melichar, Wei Hu, Rebecca Patenia, Karolina Melicharová, Stacie T Gallardo, and Ralph Freedman
Submissions from 1993
Estimation of the incidence of a rare genetic disease through a two-tier mutation survey., R Chakraborty, M R Srinivasan, and S Raskin
Submissions from 1992
Multiple alleles and estimation of genetic parameters: computational equations showing involvement of all alleles., R Chakraborty
Submissions from 1991
Inclusion of data on relatives for estimation of allele frequencies., R Chakraborty
Statistical interpretation of DNA typing data., R Chakraborty
Submissions from 1988
Parentage analysis with genetic markers in natural populations. I. The expected proportion of offspring with unambiguous paternity., R Chakraborty, T R Meagher, and P E Smouse
Population amalgamation and genetic variation: observations on artificially agglomerated tribal populations of Central and South America., R Chakraborty, P E Smouse, and J V Neel
Submissions from 1984
Detection of nonrandom association of alleles from the distribution of the number of heterozygous loci in a sample., R Chakraborty
Genetics and epidemiology of gallbladder disease in New World native peoples., K M Weiss, R E Ferrell, C L Hanis, and P N Styne
Submissions from 1982
Genetically controlled variation of "acid" beta-galactosidase detected in Rattus norvegicus by isoelectric focusing., T C Douglas, K A Kimmel, and P E Dawson
Submissions from 1979
Polymorphisms, linkage and mapping of four enzyme loci in the fish genus Xiphophorus (Poeciliidae)., D C Morizot and M J Siciliano
Submissions from 1977
Three linked enzyme loci in fishes: implications in the evolution of vertebrate chromosomes., D C Morizot, D A Wright, and M J Siciliano