Comparative Outcomes of Interventions for Femoropopliteal Chronic Total Occlusion Versus Non-Chronic Total Occlusion Lesions From the Multicenter XLPAD Registry

Authors

Shirling Tsai
Yulun Liu
Lawrence Hoang
Michael Vu
Hua Lu
Bala Ramanan
David Fernandez Vazquez
Zachary Rosol
Sameh Sayfo
Mohamad Amer Alaiti
Panagiotis Koutakis
Emmanouil S Brilakis
Mehdi H Shishehbor
Subhash Banerjee

Publication Date

6-20-2023

Journal

Journal of the American Heart Association

Abstract

Background Endovascular intervention of femoropopliteal chronic total occlusions (CTOs) is technically more complex. However, there is lack of comparative analysis between CTO and non-CTO femoropopliteal interventions. Methods and Results We report procedural details and outcomes of patients treated for femoropopliteal CTO and non-CTO lesions in the XLPAD (Excellence in Peripheral Artery Disease) registry (NCT01904851) between 2006 and 2019. Primary outcomes were procedural success and 1-year major adverse limb events, a composite of all-cause death, target limb revascularization, or major amputation. Analysis included 2895 patients (CTO: n=1516 patients; non-CTO: n=1379 patients) with 3658 lesions (CTO: n=1998 lesions; non-CTO: n=1660 lesions). Conventional balloon angioplasty (20.86% versus 33.48%,

Keywords

chronic total occlusion, femoropopliteal disease, outcomes analysis, peripheral artery disease, prospective registry