Publication Date
12-1-2022
Journal
Cellular Reprogramming
Abstract
By dissecting and comparing the transcriptional trajectories and epigenomic traits of reprogramming and transforming cells at the single-cell resolution, Huyghe et al discovered Bcl11b and Atoh8, two key transcription factors controlling cell plasticity during pluripotent reprogramming and oncogenic transformation.
Keywords
Humans, Cell Plasticity, Transcription Factors, Cell Transformation, Neoplastic, Tumor Suppressor Proteins, Cellular Reprogramming, Repressor Proteins
Included in
Biological Phenomena, Cell Phenomena, and Immunity Commons, Integrative Medicine Commons, Medical Cell Biology Commons