Precision Recruitment and Engagement of Individuals at Risk for Diabetes and Hypertension in Clinical Trials (PREDHICT): A Randomized Trial for an E-Persuasive Mobile Application to Inform Decision Making about Clinical Trials

Authors

Azizi Seixas
Shannique Richards
Jesse Q Moore
Chigozirim Izeogu
Laronda A Hollimon
Peng Jin
Girardin Jean-Louis

Publication Date

11-27-2023

Journal

International Journal of Environmental Research and Public Health

Abstract

The primary objective of this randomized trial was to test the effectiveness of the PREDHiCT digital application, which provides educational and supportive navigation to increase willingness to participate in a future clinical trial. The second objective was to test whether PREDHiCT increased clinical trial literacy or enhanced psychological facilitators of clinical trial participation, such as altruism. To test these two objectives, we conducted a 1-month remote decentralized trial with 100 participants who either have a personal or family history of cardiometabolic health conditions, such as hypertension, diabetes, and obesity. Results indicated significant changes in altruism (mean: -2.94 vs. 0.83;

Keywords

decentralized trials, clinical trial, health literacy, altruism