Title

An update on pathobiologic roles of anti-glycan antibodies in Guillain-Barré syndrome.

Publication Date

1-1-2010

Journal

F1000 Biol Rep. 2010; 2: 21.

Abstract

Anti-glycan antibodies directed against gangliosides are now considered the major immune effectors that induce damage to intact nerve fibers in some variants of the monophasic neuropathic disorders that comprise Guillain-Barré syndrome. Recent experimental studies elucidating the complexity of anti-glycan antibody-mediated pathobiologic effects on intact and injured nerves undergoing repair are discussed.