HuD Stimulates Translation via eIF4A

Authors

Chyi-Ying A Chen
Ann-Bin Shyu

Publication Date

12-25-2009

Journal

Molecular Cell

Abstract

In this issue of Molecular Cell, Fukao et al. (2009) report that HuD upregulates mRNA translation through direct interaction with eIF4A in the 5' cap-binding complex, revealing a posttranscriptional role for HuD in neuronal development and plasticity.

Keywords

Animals, Cell Line, Eukaryotic Initiation Factor-4A, Hu Paraneoplastic Encephalomyelitis Antigens, Humans, Protein Biosynthesis, RNA, Messenger

DOI

10.1016/j.molcel.2009.12.013

PMID

20064457

PMCID

PMC2995272

PubMedCentral® Posted Date

December 2010

PubMedCentral® Full Text Version

Author MSS

Published Open-Access

yes