HuD stimulates translation via eIF4A.
Mol Cell. 2009 December 25; 36(6): 920–921.
In this issue of Molecular Cell, Fukao et al. (2009) report that HuD upregulates mRNA translation through direct interaction with eIF4A in the 5' cap-binding complex, revealing a posttranscriptional role for HuD in neuronal development and plasticity.
Animals, Cell Line, Eukaryotic Initiation Factor-4A, Hu Paraneoplastic Encephalomyelitis Antigens, Humans, Protein Biosynthesis, RNA, Messenger