Open-access full-text journal articles from UT Medical School from 1999-present

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Submissions from 2009

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Active water in protein-protein communication within the membrane: the case of SRII-HtrII signal relay., Vladislav B Bergo, Elena N Spudich, John L Spudich, and Kenneth J Rothschild

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Adenine nucleotide-dependent regulation of assembly of bacterial tubulin-like FtsZ by a hypermorph of bacterial actin-like FtsA., Tushar K Beuria, Srinivas Mullapudi, Eugenia Mileykovskaya, Mahalakshmi Sadasivam, William Dowhan, and William Margolin

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Molecular basis for class V beta-tubulin effects on microtubule assembly and paclitaxel resistance., Rajat Bhattacharya and Fernando Cabral

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PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores., Perry E Bickel, John T Tansey, and Michael A Welte

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Lipid-protein interactions drive membrane protein topogenesis in accordance with the positive inside rule., Mikhail Bogdanov, Jun Xie, and William Dowhan

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Localized diacylglycerol-dependent stimulation of Ras and Rap1 during phagocytosis., Roberto J Botelho, Rene E Harrison, James C Stone, John F Hancock, Mark R Philips, Jenny Jongstra-Bilen, David Mason, Jonathan Plumb, Michael R Gold, and Sergio Grinstein

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A randomized, double-blind, placebo-controlled pilot study of naltrexone in outpatients with bipolar disorder and alcohol dependence., E Sherwood Brown, Thomas J Carmody, Joy M Schmitz, Raul Caetano, Bryon Adinoff, Alan C Swann, and A John Rush

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Regulation of hepatic cytochrome P450 expression in mice with intestinal or systemic infections of citrobacter rodentium., Madhusudana R Chaluvadi, Ryan D Kinloch, Beatrice A Nyagode, Terrilyn A Richardson, Malik J Raynor, Melanie Sherman, Leposava Antonovic, Henry W Strobel, Dirck L Dillehay, and Edward T Morgan

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HuD stimulates translation via eIF4A., Chyi-Ying A Chen and Ann-Bin Shyu

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Ago-TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps., Chyi-Ying A Chen, Dinghai Zheng, Zhenfang Xia, and Ann-Bin Shyu

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Computational selection of inhibitors of Abeta aggregation and neuronal toxicity., Deliang Chen, Zane S Martin, Claudio Soto, and Catherine H Schein

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Genomic screening identifies novel linkages and provides further evidence for a role of MYH9 in nonsyndromic cleft lip and palate., Brett T Chiquet, Syed S Hashmi, Robin Henry, Amber Burt, John B Mulliken, Samuel Stal, Molly Bray, Susan H Blanton, and Jacqueline T Hecht

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A trilocus sequence typing scheme for hospital epidemiology and subspecies differentiation of an important nosocomial pathogen, Enterococcus faecalis., Shahreen A Chowdhury, Cesar A Arias, Sreedhar R Nallapareddy, Jinnethe Reyes, Rob J L Willems, and Barbara E Murray

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Post-translational regulation of an Aplysia glutamate transporter during long-term facilitation., Maria Sol Collado, Omar Khabour, Diasinou Fioravante, John H. Byrne, and Arnold Eskin

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Detailed analysis of sequence changes occurring during vlsE antigenic variation in the mouse model of Borrelia burgdorferi infection., Loïc Coutte, Douglas J Botkin, Lihui Gao, and Steven J Norris

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Detailed analysis of sequence changes occurring during vlsE antigenic variation in the mouse model of Borrelia burgdorferi infection., Loïc Coutte, Douglas J. Botkin, Lihui Gao, and Steven J. Norris

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Polysensory interneuronal projections to foot contractile pedal neurons in Hermissenda., Terry Crow and Lian-Ming Tian

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Validity assessment of the Breast Cancer Risk Reduction Health Belief scale., Mfon Cyrus-David, Jason King, Therese Bevers, and Emily Robinson

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Sulforaphane improves cognitive function administered following traumatic brain injury., Pramod K Dash, Jing Zhao, Sara A Orsi, Min Zhang, and Anthony N Moore

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Improved cerebellar tissue classification on magnetic resonance images of brain., Sushmita Datta, Guozhi Tao, Renjie He, Jerry S Wolinsky, and Ponnada A Narayana

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Strong-meter and weak-meter rhythm identification in spina bifida meningomyelocele and volumetric parcellation of rhythm-relevant cerebellar regions., Maureen Dennis, Talar Hopyan, Jenifer Juranek, Paul T Cirino, Khader M Hasan, and Jack Fletcher

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Molecular genetic approaches to defining lipid function., William Dowhan

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Physical and functional interaction between the dopamine transporter and the synaptic vesicle protein synaptogyrin-3., Loreto A Egaña, Rolando A Cuevas, Tracy B Baust, Leonardo A Parra, Rehana K Leak, Sarah Hochendoner, Karina Peña, Marisol Quiroz, Weimin C Hong, Mario M Dorostkar, Roger Janz, Harald H Sitte, and Gonzalo E Torres

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Genetic and hormonal factors modulate spreading depression and transient hemiparesis in mouse models of familial hemiplegic migraine type 1., Katharina Eikermann-Haerter, Ergin Dileköz, Chiho Kudo, Sean I Savitz, Christian Waeber, Michael J Baum, Michel D Ferrari, Arn M J M van den Maagdenberg, Michael A Moskowitz, and Cenk Ayata

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Altered transmission of HOX and apoptotic SNPs identify a potential common pathway for clubfoot., Audrey R Ester, Katelyn S Weymouth, Amber Burt, Carol A Wise, Allison Scott, Christina A Gurnett, Matthew B Dobbs, Susan H Blanton, and Jacqueline T Hecht

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Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation., Marc R Fabian, Géraldine Mathonnet, Thomas Sundermeier, Hansruedi Mathys, Jakob T Zipprich, Yuri V Svitkin, Fabiola Rivas, Martin Jinek, James Wohlschlegel, Jennifer A Doudna, Chyi-Ying A Chen, Ann-Bin Shyu, John R Yates, Gregory J Hannon, Witold Filipowicz, Thomas F Duchaine, and Nahum Sonenberg

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Morphoproteomic evidence of constitutively activated and overexpressed mTOR pathway in cervical squamous carcinoma and high grade squamous intraepithelial lesions., Wei Feng, Xiuzhen Duan, Jinsong Liu, Jianguo Xiao, and Robert E Brown

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High-sensitivity rod photoreceptor input to the blue-yellow color opponent pathway in macaque retina., Greg D Field, Martin Greschner, Jeffrey L Gauthier, Carolina Rangel, Jonathon Shlens, Alexander Sher, David W Marshak, Alan M Litke, and E J Chichilnisky

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Optical imaging of postsynaptic odor representation in the glomerular layer of the mouse olfactory bulb., Max L Fletcher, Arjun V Masurkar, Junling Xing, Fumiaki Imamura, Wenhui Xiong, Shin Nagayama, Hiroki Mutoh, Charles A Greer, Thomas Knöpfel, and Wei R Chen

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Analysis of clonality and antibiotic resistance among early clinical isolates of Enterococcus faecium in the United States., Jessica R Galloway-Peña, Sreedhar R Nallapareddy, Cesar A Arias, George M Eliopoulos, and Barbara E Murray

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Learning reward timing in cortex through reward dependent expression of synaptic plasticity., Jeffrey P Gavornik, Marshall G Hussain Shuler, Yonatan Loewenstein, Mark F Bear, and Harel Z Shouval

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Intravenous mesenchymal stem cell therapy for traumatic brain injury., Matthew T Harting, Fernando Jimenez, Hasan Xue, Uwe M Fischer, James Baumgartner, Pramod K Dash, and Charles S Cox

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Subacute neural stem cell therapy for traumatic brain injury., Matthew T Harting, Leeann E Sloan, Fernando Jimenez, James Baumgartner, and Charles S Cox

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Reduced vascular endothelial growth factor expression in contusive spinal cord injury., Juan J Herrera, Olivera Nesic, and Ponnada A Narayana

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TB research at UT-Houston--a review of cord factor: new approaches to drugs, vaccines and the pathogenesis of tuberculosis., Robert L Hunter, Lisa Armitige, Chinnaswamy Jagannath, and Jeffrey K Actor

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Explanations for unsuccessful weight loss among bariatric surgery candidates., Kevin O Hwang, Joseph H Childs, G Ken Goodrick, Wael A Aboughali, Eric J Thomas, Craig W Johnson, Sherman C Yu, and Elmer V Bernstam

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Screening for obstructive sleep apnea on the internet: randomized trial., Kevin O Hwang, Abdurrahman M Hamadah, Craig W Johnson, Eric J Thomas, G Ken Goodrick, and Elmer V Bernstam

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The detrimental role of angiotensin receptor agonistic autoantibodies in intrauterine growth restriction seen in preeclampsia., Roxanna A Irani, Yujin Zhang, Sean C Blackwell, Cissy Chenyi Zhou, Susan M Ramin, Rodney E Kellems, and Yang Xia

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5-HT and GABA modulate intrinsic excitability of type I interneurons in Hermissenda., Nan Ge Jin, Lian-Ming Tian, and Terry Crow

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Irresistible curves., Jennifer R Juarez and William Margolin

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Hybrid stochastic simulations of intracellular reaction-diffusion systems., Georgios Kalantzis

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Evaluating statistical methods used to estimate the number of postsynaptic receptors., Georgios Kalantzis, Yoshira Kubota, and Harel Z Shouval

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Structural plasticity can produce metaplasticity., Georgios Kalantzis and Harel Z Shouval

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The use of second-generation antipsychotics and the changes in physical growth in children and adolescents with perinatally acquired HIV., Suad Kapetanovic, Lisa Aaron, Grace Montepiedra, Patricia A Sirois, James M Oleske, Kathleen Malee, Deborah A Pearson, Sharon L Nichols, Patricia A Garvie, John Farley, Molly L Nozyce, Mark Mintz, and Paige L Williams

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Is paromomycin an effective and safe treatment against cutaneous leishmaniasis? A meta-analysis of 14 randomized controlled trials., Dae Hyun Kim, Hye Jin Chung, Joachim Bleys, and Reza F Ghohestani

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Mechanism for sortase localization and the role of sortase localization in efficient pilus assembly in Enterococcus faecalis., Kimberly A Kline, Andrew L Kau, Swaine L Chen, Adeline Lim, Jerome S Pinkner, Jason Rosch, Sreedhar R Nallapareddy, Barbara E Murray, Birgitta Henriques-Normark, Wandy Beatty, Michael G Caparon, and Scott J Hultgren

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Dopamine-stimulated dephosphorylation of connexin 36 mediates AII amacrine cell uncoupling., W Wade Kothmann, Stephen C Massey, and John O'Brien

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Long-lasting hyperexcitability induced by depolarization in the absence of detectable Ca2+ signals., Kumud K Kunjilwar, Harvey M Fishman, Dario J Englot, Roger G O'Neil, and Edgar T Walters

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Changes in the PQRST intervals and heart rate variability associated with rewarming in two newborns undergoing hypothermia therapy., Robert E Lasky, Nehal A Parikh, Amber L Williams, Nikhil S Padhye, and Seetha Shankaran

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Organization of hue selectivity in macaque V2 thin stripes., Heejin Lim, Yi Wang, Youping Xiao, Ming Hu, and Daniel J Felleman

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Intact flagellar motor of Borrelia burgdorferi revealed by cryo-electron tomography: evidence for stator ring curvature and rotor/C-ring assembly flexion., Jun Liu, Tao Lin, Douglas J Botkin, Erin McCrum, Hanspeter Winkler, and Steven J Norris

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Ultraviolet radiation intensity predicts the relative distribution of dermatomyositis and anti-Mi-2 autoantibodies in women., Lori A Love, Clarice R Weinberg, D Robert McConnaughey, Chester V Oddis, Thomas A Medsger, John D Reveille, Frank C Arnett, Ira N Targoff, and Frederick W Miller

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Following the "herb"., Gerald W Mank

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BTG/TOB factors impact deadenylases., Fabienne Mauxion, Chyi-Ying A Chen, Bertrand Séraphin, and Ann-Bin Shyu

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Synaptotagmin-2 controls regulated exocytosis but not other secretory responses of mast cells., Ernestina Melicoff, Leticia Sansores-Garcia, Alejandra Gomez, Daniel C Moreira, Proleta Datta, Pratima Thakur, Youlia Petrova, Tanya Siddiqi, Jayasimha N Murthy, Burton F Dickey, Ruth Heidelberger, and Roberto Adachi

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Cardiolipin membrane domains in prokaryotes and eukaryotes., Eugenia Mileykovskaya and William Dowhan

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Cross currents in protein misfolding disorders: interactions and therapy., Rodrigo Morales, Kristi M Green, and Claudio Soto

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ANKRD1, the gene encoding cardiac ankyrin repeat protein, is a novel dilated cardiomyopathy gene., Mousumi Moulik, Matteo Vatta, Stephanie H Witt, Anita M Arola, Ross T Murphy, William J McKenna, Aladin M Boriek, Kazuhiro Oka, Siegfried Labeit, Neil E Bowles, Takuro Arimura, Akinori Kimura, and Jeffrey A Towbin

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Inoculum effect with cefazolin among clinical isolates of methicillin-susceptible Staphylococcus aureus: frequency and possible cause of cefazolin treatment failure., Esteban C Nannini, Martin E Stryjewski, Kavindra V Singh, Agathe Bourgogne, Tom H Rude, G Ralph Corey, Vance G Fowler, and Barbara E Murray

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Diffusion tensor imaging of cocaine-treated rodents., Ponnada A Narayana, Pallavi Ahobila-Vajjula, Jaivijay Ramu, Juan Herrera, Joel L Steinberg, and F Gerard Moeller

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A loss-of-function variant of PTPN22 is associated with reduced risk of systemic lupus erythematosus., Valeria Orrú, Sophia J Tsai, Blanca Rueda, Edoardo Fiorillo, Stephanie M Stanford, Jhimli Dasgupta, Jaana Hartiala, Lei Zhao, Norberto Ortego-Centeno, Sandra D'Alfonso, Frank C Arnett, Hui Wu, Miguel A Gonzalez-Gay, Betty P Tsao, Bernardo Pons-Estel, Marta E Alarcon-Riquelme, Yantao He, Zhong-Yin Zhang, Hooman Allayee, Xiaojiang S Chen, Javier Martin, and Nunzio Bottini

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Activity of anidulafungin in a murine model of Candida krusei infection: evaluation of mortality and disease burden by quantitative tissue cultures and measurement of serum (1,3)-beta-D-glucan levels., Luis Ostrosky-Zeichner, Victor L Paetznick, Jose Rodriguez, Enuo Chen, and Daniel J Sheehan

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Heart rate variability in response to pain stimulus in VLBW infants followed longitudinally during NICU stay., Nikhil S Padhye, Amber L Williams, Asif Z Khattak, and Robert E Lasky

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Migraine and vasodepressor syncope in a large family., Robert D Paisley, Harvinder S Arora, Alireza Nazeri, Ali Massumi, and Mehdi Razavi

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Volumetric and anatomical MRI for hypoxic-ischemic encephalopathy: relationship to hypothermia therapy and neurosensory impairments., N A Parikh, R E Lasky, C N Garza, E Bonfante-Mejia, S Shankaran, and J E Tyson

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Effect of VEGF treatment on the blood-spinal cord barrier permeability in experimental spinal cord injury: dynamic contrast-enhanced magnetic resonance imaging., Chirag B Patel, David M Cohen, Pallavi Ahobila-Vajjula, Laura M Sundberg, Tessy Chacko, and Ponnada A Narayana

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Relationship between threshold and suprathreshold perception of position and stereoscopic depth., Saumil S Patel, Harold E Bedell, Dorcas K Tsang, and Michael T Ukwade

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Intra-hippocampal administration of the VEGF receptor blocker PTK787/ZK222584 impairs long-term memory., Shibani Pati, Sara A Orsi, Anthony N Moore, and Pramod K Dash

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Adenosine signaling contributes to ethanol-induced fatty liver in mice., Zhongsheng Peng, Pier Andrea Borea, Katia Varani, Tuere Wilder, Herman Yee, Luis Chiriboga, Michael R Blackburn, Gianfranco Azzena, Giuseppe Resta, and Bruce N Cronstein

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Prion protein glycosylation is not required for strain-specific neurotropism., Justin R Piro, Brent T Harris, Koren Nishina, Claudio Soto, Rodrigo Morales, Judy R Rees, and Surachai Supattapone

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Upregulation of defensins in burn sheep small intestine., Brian J Poindexter, Gordon L Klein, Stephen M Milner, and Roger J Bick

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Rubisco in complex with Rubisco large subunit methyltransferase., Stefan Raunser, Roberta Magnani, Zhong Huang, Robert L Houtz, Raymond C Trievel, Pawel A Penczek, and Thomas Walz

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Dissemination of methicillin-resistant Staphylococcus aureus USA300 sequence type 8 lineage in Latin America., Jinnethe Reyes, Sandra Rincón, Lorena Díaz, Diana Panesso, Germán A Contreras, Jeannete Zurita, Carlos Carrillo, Adele Rizzi, Manuel Guzmán, Javier Adachi, Shahreen Chowdhury, Barbara E Murray, and Cesar A Arias

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Does colon cancer ever metastasize to bone first? a temporal analysis of colorectal cancer progression., Eira S Roth, David T Fetzer, Bruce J Barron, Usha A Joseph, Isis W Gayed, and David Q Wan

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Cardiolipin biosynthesis and remodeling enzymes are altered during development of heart failure., Harjot K Saini-Chohan, Michael G Holmes, Adam J Chicco, William A Taylor, Russell L Moore, Sylvia A McCune, Diane L Hickson-Bick, Grant M Hatch, and Genevieve C Sparagna

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Proton magnetic resonance spectroscopy in multiple sclerosis., Balasrinivasa R Sajja, Jerry S Wolinsky, and Ponnada A Narayana

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Sequencing of TGF-beta pathway genes in familial cases of intracranial aneurysm., Teresa Santiago-Sim, Sumy Mathew-Joseph, Hariyadarshi Pannu, Dianna M Milewicz, Christine E Seidman, J G Seidman, and Dong H Kim

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Pancreatic adenocarcinoma in a patient with situs inversus: a case report of this rare coincidence., Eric L Sceusi and Curtis J Wray

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A family of fibrinogen-binding MSCRAMMs from Enterococcus faecalis., Jouko Sillanpää, Sreedhar R Nallapareddy, Janeu Houston, Vannakambadi K Ganesh, Agathe Bourgogne, Kavindra V Singh, Barbara E Murray, and Magnus Höök

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Distribution of genes encoding MSCRAMMs and Pili in clinical and natural populations of Enterococcus faecium., Jouko Sillanpää, Vittal P Prakash, Sreedhar R Nallapareddy, and Barbara E Murray

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Timely follow-up of abnormal diagnostic imaging test results in an outpatient setting: are electronic medical records achieving their potential?, Hardeep Singh, Eric J Thomas, Shrinidi Mani, Dean Sittig, Harvinder Arora, Donna Espadas, Myrna M Khan, and Laura A Petersen

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Impact of medications prescribed for treatment of attention-deficit hyperactivity disorder on physical growth in children and adolescents with HIV., Patricia A Sirois, Grace Montepiedra, Suad Kapetanovic, Paige L Williams, Deborah A Pearson, Kathleen Malee, Patricia A Garvie, Betsy L Kammerer, Sharon L Nichols, Molly L Nozyce, Mark Mintz, Wendy G Mitchell, and James M Oleske

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Interlinked dual-time feedback loops can enhance robustness to stochasticity and persistence of memory., Paul Smolen, Douglas A Baxter, and John H Byrne

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Mutation analysis of the PVRL1 gene in caucasians with nonsyndromic cleft lip/palate., Mehmet A Sözen, Jacqueline T Hecht, and Richard A Spritz

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Mutation and association analysis of the PVR and PVRL2 genes in patients with non-syndromic cleft lip and palate., Mehmet A Sözen, Jacqueline T Hecht, and Richard A Spritz

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Do binucleate cardiomyocytes have a role in myocardial repair? Insights using isolated rodent myocytes and cell culture., Michael J Stephen, Brian J Poindexter, Johan A Moolman, David Sheikh-Hamad, and Roger J Bick

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Opioid dependence treatment: options in pharmacotherapy., Angela L Stotts, Carrie L Dodrill, and Thomas R Kosten

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Ultrasound feedback and motivational interviewing targeting smoking cessation in the second and third trimesters of pregnancy., Angela L Stotts, Janet Y Groff, Mary M Velasquez, Ruby Benjamin-Garner, Charles Green, Joseph P Carbonari, and Carlo C DiClemente

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Using Acceptance and Commitment Therapy during Methadone Dose Reduction: Rationale, Treatment Description, and a Case Report., Angela L Stotts, Akihiko Masuda, and Kelly Wilson

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Ketamine-induced hepatoprotection: the role of heme oxygenase-1., James W Suliburk, Jeremy L Ward, Kenneth S Helmer, Sasha D Adams, Brian S Zuckerbraun, and David W Mercer

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Continuum of depressive and manic mixed states in patients with bipolar disorder: quantitative measurement and clinical features., Alan C Swann, Joel L Steinberg, Marijn Lijffijt, and Gerard F Moeller

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Intracranial EEG reveals a time- and frequency-specific role for the right inferior frontal gyrus and primary motor cortex in stopping initiated responses., Nicole Swann, Nitin Tandon, Ryan Canolty, Timothy M Ellmore, Linda K McEvoy, Stephen Dreyer, Michael DiSano, and Adam R Aron

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Deep gray matter atrophy in multiple sclerosis: a tensor based morphometry., Guozhi Tao, Sushmita Datta, Renjie He, Flavia Nelson, Jerry S Wolinsky, and Ponnada A Narayana

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Symmetric inverse consistent nonlinear registration driven by mutual information., Guozhi Tao, Renjie He, Sushmita Datta, and Ponnada A Narayana

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Further characterization of the epa gene cluster and Epa polysaccharides of Enterococcus faecalis., Fang Teng, Kavindra V Singh, Agathe Bourgogne, Jing Zeng, and Barbara E Murray

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Body weight, insulin resistance, and serum adipokine levels 2 years after 2 types of bariatric surgery., Michael A Trakhtenbroit, Joshua G Leichman, Mohamed F Algahim, Charles C Miller, Frank G Moody, Thomas R Lux, and Heinrich Taegtmeyer

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Phase I clinical trials in 56 patients with thyroid cancer: the M. D. Anderson Cancer Center experience., Apostolia Maria Tsimberidou, Christos Vaklavas, Sijin Wen, David Hong, Jennifer Wheler, Chaan Ng, Aung Naing, Susan Tse, Naifa Busaidy, Maurie Markman, Steven I Sherman, and Razelle Kurzrock

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Cost-effectiveness of universal prophylaxis in pregnancy with prior group B streptococci colonization., Mark A Turrentine, Mildred M Ramirez, and Joan M Mastrobattista

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Advances in progenitor cell therapy using scaffolding constructs for central nervous system injury., Peter A Walker, Kevin R Aroom, Fernando Jimenez, Shinil K Shah, Matthew T Harting, Brijesh S Gill, and Charles S Cox

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Modern approaches to pediatric brain injury therapy., Peter A Walker, Matthew T Harting, James E Baumgartner, Stephen Fletcher, Nathan Strobel, and Charles S Cox