Faculty, Staff and Student Publications

Authors

    Language

    English

    Publication Date

    8-27-2022

    Journal

    Bulletin of Mathematical Biology

    DOI

    10.1007/s11538-022-01064-w

    PMID

    36029391

    PMCID

    PMC9418661

    PubMedCentral® Posted Date

    August 2022

    PubMedCentral® Full Text Version

    Post-print

    Abstract

    As the availability of COVID-19 vaccines, it is badly needed to develop vaccination guidelines to prioritize the vaccination delivery in order to effectively stop COVID-19 epidemic and minimize the loss. We evaluated the effect of age-specific vaccination strategies on the number of infections and deaths using an SEIR model, considering the age structure and social contact patterns for different age groups for each of different countries. In general, the vaccination priority should be given to those younger people who are active in social contacts to minimize the number of infections, while the vaccination priority should be given to the elderly to minimize the number of deaths. But this principle may not always apply when the interaction of age structure and age-specific social contact patterns is complicated. Partially reopening schools, workplaces or households, the vaccination priority may need to be adjusted accordingly. Prematurely reopening social contacts could initiate a new outbreak or even a new pandemic out of control if the vaccination rate and the detection rate are not high enough. Our result suggests that it requires at least nine months of vaccination (with a high vaccination rate > 0.1%) for Italy and India before fully reopening social contacts in order to avoid a new pandemic.

    Keywords

    Age structure, Vaccination strategy, COVID-19 control, Reopening policy, Social contact

    Published Open-Access

    yes

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