Publication Date

12-21-2022

Journal

Journal of Clinical Medicine

DOI

10.3390/jcm12010058

PMID

36614855

PMCID

PMC9821081

PubMedCentral® Posted Date

12-21-2022

PubMedCentral® Full Text Version

Post-print

Published Open-Access

yes

Keywords

fetal brain tumor, macrocephaly, teratoma, hydrocephalus, prenatal imaging

Abstract

Fetal brain tumors are a rare entity with an overall guarded prognosis. About 10% of congenital brain tumors are diagnosed during fetal life. They differ from the postnatally encountered pediatric brain tumors with respect to location and tumor type. Fetal brain tumors can be benign or malignant and infiltrate or displace adjacent brain structures. Due to their high mitotic rate, they can show rapid growth. Outcome depends on age of diagnosis, size, and histological tumor type. Findings like polyhydramnios and macrocephaly encountered on routine ultrasound are frequently associated. Detailed prenatal anomaly scan and subsequent fetal magnetic resonance imaging (MRI) may identify the brain tumor and its severity. Both maternal and fetal prognosis should be included in prenatal counselling and decision making.

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