Invasive Group A Streptococcus in Infants Less Than 1-year of Age From 2012 to 2022: A Single-Center Experience

Authors

Taylor Nack
Jesus G Vallejo
James Dunn
Anthony R Flores
J Chase McNeil

Publication Date

1-29-2024

Journal

Journal of the Pediatric Infectious Diseases Society

DOI

10.1093/jpids/piad105

PMID

37978871

PMCID

PMC10824259

PubMedCentral® Posted Date

11-18-2023

PubMedCentral® Full Text Version

Post-print

Published Open-Access

yes

Keywords

Infant, Humans, Pandemics, Streptococcus pyogenes, Streptococcal Infections, Anti-Bacterial Agents, Incidence, GAS, infant, invasive infection, pediatric, Streptococcus pyogenes

Abstract

The incidence of invasive Group A Streptococcus (iGAS) has varied throughout the COVID-19 pandemic. We reviewed iGAS infections in infants ≤1 year from 2012 to 2022. Twenty-five percent of cases occurred in the last quarter of 2022. Pneumonia (21.8%) was the most common presentation. Twenty-one patients (65.6%) were successfully transitioned to oral antibiotics.