Publication Date
3-1-2024
Journal
Pediatric Nephrology
DOI
10.1007/s00467-023-06186-4
PMID
37930418
PMCID
PMC10817827
PubMedCentral® Posted Date
11-6-2023
PubMedCentral® Full Text Version
Post-print
Published Open-Access
yes
Keywords
Humans, Child, Critical Illness, Acute Disease, Renal Replacement Therapy, Renal Dialysis, Acute Kidney Injury, Kidney, AKI, CRRT, Dialysis, CVVH, Critical care
Abstract
Pediatric acute kidney support therapy (paKST) programs aim to reliably provide safe, effective, and timely extracorporeal supportive care for acutely and critically ill pediatric patients with acute kidney injury (AKI), fluid and electrolyte derangements, and/or toxin accumulation with a goal of improving both hospital-based and lifelong outcomes. Little is known about optimal ways to configure paKST teams and programs, pediatric-specific aspects of delivering high-quality paKST, strategies for transitioning from acute continuous modes of paKST to facilitate rehabilitation, or providing effective short- and long-term follow-up. As part of the 26th Acute Disease Quality Initiative Conference, the first to focus on a pediatric population, we summarize here the current state of knowledge in paKST programs and technology, identify key knowledge gaps in the field, and propose a framework for current best practices and future research in paKST.