Publication Date
5-1-2024
Journal
JPGN Reports
DOI
10.1002/jpr3.12041
PMID
38756121
PMCID
PMC11093934
PubMedCentral® Posted Date
2-12-2024
PubMedCentral® Full Text Version
Post-print
Published Open-Access
yes
Keywords
drug induced liver injury, herbal and dietary supplements, Herbalife®, liver failure
Abstract
Herbal and dietary supplements (HDS) are a common etiology of drug induced liver injury and, specifically, Herbalife® supplements have been implicated. Hepatitis associated aplastic anemia (HAAA) is a rare and potentially fatal complication after acute hepatitis characterized by pancytopenia. While there have been rare cases of HDS leading to HAAA, no cases of Herbalife® induced liver injury leading to HAAA have been reported from this specific HDS. We report a unique case of severe aplastic anemia developing after sub-fulminant liver failure associated with chronic HDS use. This case illustrates the importance of warning the public about HDS as their use continues to increase. It is not only important to recognize HDS as etiology, but also for healthcare providers to carefully monitor these patients after resolution of liver injury for the development of HAAA.
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Digestive System Diseases Commons, Gastroenterology Commons, Hepatology Commons, Medical Sciences Commons, Pediatrics Commons