Diagnosis and Management of Shrimp Allergy

Authors

Bin Brenda Su
Warren Blackmon
Chun Xu
Christopher Holt
Nathaniel Boateng
Darren Wang
Vibha Szafron
Aikaterini Anagnostou
Sara Anvari
Carla M Davis

Publication Date

1-1-2024

Journal

Frontiers in Allergy

DOI

10.3389/falgy.2024.1456999

PMID

39493746

PMCID

PMC11527777

PubMedCentral® Posted Date

10-18-2024

PubMedCentral® Full Text Version

Post-print

Published Open-Access

yes

Keywords

shrimp allergy, genetics, environmental exposure, diagnosis, management, specific IgE

Abstract

Shrimp allergy, the most common food allergy in the United States, affects up to 2% of the population. Its etiology is multi-factorial with the combination of genetic predisposition and environmental exposures. This review summarizes the latest diagnosis and management strategies for shrimp allergy. Currently, the double-blind, placebo-controlled food challenge is the gold standard for diagnosis. Moreover, mainstream and experimental management strategies include food allergen avoidance, the FDA-approved omalizumab, and oral immunotherapy. Herein, we emphasize the urgent need to develop more effective diagnostic tools and therapies for shrimp allergy.