Medication-Induced Mood Disorders Following Epidural Steroid Injections in Patients With Pain: A Case Series

Authors

Christian T Vangeison
Joseph P Roys
Marissa N Catalanotto
Wyatt I Kupperman
Alexander R Kovacs
Dan Sebastian Dîrzu
Emanuel N Husu

Publication Date

6-1-2023

Journal

Clinical Case Reports

DOI

10.1002/ccr3.7415

PMID

37251746

PMCID

PMC10213705

PubMedCentral® Posted Date

5-25-2023

PubMedCentral® Full Text Version

Post-print

Published Open-Access

yes

Keywords

case report, epidural steroid injection induced mood disorder, medication‐induced mood disorder, substance‐induced mood disorder

Abstract

KEY CLINICAL MESSAGE: Medication-induced mood disorders following epidural steroid injections are possible therefore should be disclosed to the patient.

ABSTRACT: Medication-induced mood disorders have been rarely reported following epidural steroid injections (ESI). This case series presents three patients who met the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria for substance/medication-induced mood disorder after an ESI. In considering a candidacy for ESI, the rare but significant, side effects of psychiatric side effects should be disclosed to patients.