Publication Date

5-1-2024

Journal

Journal of Autism and Developmental Disorders

DOI

10.1007/s10803-023-05912-z

PMID

36847894

PMCID

PMC11846066

PubMedCentral® Posted Date

2-22-2025

PubMedCentral® Full Text Version

Author MSS

Published Open-Access

yes

Keywords

Humans, Cognitive Behavioral Therapy, Male, Female, Child, Anxiety, Autistic Disorder, Treatment Outcome, Severity of Illness Index, Child, Preschool, Social Interaction, Autism Spectrum Disorder, Autism spectrum disorder, Anxiety, Treatment, Cognitive behavioral therapy, Obsessive-compulsive disorder, Assessment

Abstract

PURPOSE: Using data from a randomized clinical trial evaluating cognitive behavioral therapy (CBT) for children with autism and co-occurring anxiety, this study examined the relationship between autism features and anxiety symptoms throughout CBT.

METHODS: Two multilevel mediation analyses were run which examined the mediating role of changes in anxiety for changes in two core features of autism, (a) repetitive and restrictive behaviors (RRBs) and (b) social communication/interaction impairments, between pre- and post-treatment.

RESULTS: Indirect effects between time and autism characteristics were significant for both models, indicating that as anxiety changes, so do RRBs and social communication/interaction as the outcomes respectively.

CONCLUSION: Findings suggest a bidirectional relationship between anxiety and autism features. Implications of these findings are discussed.

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