CIRCADIAN RHYTHM IN THE BIOAVAILABILITY OF ORALLY ADMINISTERED THEOPHYLLINE

GLENNA MAXEY KYLE, The University of Texas School of Public Health

Abstract

The effect of time (i.e., biologic time structure) of drug administration on the bioavailability of theophylline was investigated in man after both a single dosage as well as after repeated, or chronic, drug administrations. Preliminary laboratory investigations on Balb-C mice showed the toxic

Subject Area

Pharmacology

Recommended Citation

KYLE, GLENNA MAXEY, "CIRCADIAN RHYTHM IN THE BIOAVAILABILITY OF ORALLY ADMINISTERED THEOPHYLLINE" (1979). Texas Medical Center Dissertations (via ProQuest). AAI8112521.
https://digitalcommons.library.tmc.edu/dissertations/AAI8112521

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