Part of the Biochemistry, Biophysics, and Structural Biology Commons

Works in Biochemistry, Biophysics, and Structural Biology

2023

Regulation and Function of ZEB1 Acetylation in Lung Adenocarcinoma Progression and Metastasis, Mabel Perez-Oquendo
Dissertations and Theses (Open Access)

PDF

TARGETING METABOLIC ALTERATIONS ASSOCIATED WITH SMOOTH MUSCLE α-ACTIN PATHOGENIC VARIANT ATTENUATES MOYAMOYA-LIKE CEREBROVASCULAR DISEASE, Anita Kaw
Dissertations and Theses (Open Access)

PDF

ELUCIDATING THE DIRECT ROLE OF M6A IN THE HUMAN TRANSCRIPTOME, Lana Al Hasani
Dissertations and Theses (Open Access)

PDF

S-Acylation is a Key Regulator of Orai1/STIM1-Mediated Store-Operated Calcium Entry in T Cells, Savannah J. West Diaz
Dissertations and Theses (Open Access)

PDF

2022

ANKYRIN DEPENDENT MITOCHONDRIAL FUNCTION AND BIOENERGETICS IN THE HEART, Janani Subramaniam, Janani Subramaniam
Dissertations and Theses (Open Access)

PDF

Lipid composition and configuration drive biophysical properties of the mammalian plasma membrane, Jessica L. Symons
Dissertations and Theses (Open Access)

PDF

The Role of the Hypoxia-Inducible Factor 2 in Pancreatic Cancer: Mechanisms of Tumor Immunosuppression and Intestinal Radioprotection, Carolina Garcia Garcia
Dissertations and Theses (Open Access)

PDF

GRK3 CONNECTS ANGIOGENESIS AND NEUROENDOCRINE DIFFERENTIATION IN PROSTATE CANCER BY ACTIVATING HDAC2 THAT EPIGENETICALLY REPRESSES TSP1 AND REST, Samira Naderinezhad
Dissertations and Theses (Open Access)

PDF

Regulation of systemic and cellular metabolism in prostate cancer by CAMKK2 and elucidation of ATGL’s role in disease progression, Dominik Awad
Dissertations and Theses (Open Access)

PDF

NOVEL REGULATORS OF CELLULAR SECRETION ALTER THE TUMOR MICROENVIRONMENT TO DRIVE METASTASIS, Rakhee Bajaj
Dissertations and Theses (Open Access)

PDF

Modulation of KRAS Structure and Dynamics by KRAS Ubiquitination and Membrane Depolarization, Vinay Nair
Dissertations and Theses (Open Access)

PDF

An Investigation of Epigenetic Mechanisms Driving the Biology of Head and Neck Squamous Cell Carcinoma, Scot Carson Callahan
Dissertations and Theses (Open Access)

PDF

TISSUE-SPECIFIC MATRIX CONTROL OF CELL COHESION AND MIGRATION SIGNALING COMPLEXES, Tristen Tellman
Dissertations and Theses (Open Access)

PDF

Plant Homeodomain Finger Protein 20 (PHF20) and its Homolog PHF20 Like 1 (PHF20L1) Define Two Distinct Non-Specific Lethal (NSL) Complexes, Hieu Van, Hieu T. Van
Dissertations and Theses (Open Access)

PDF

2021

INVESTIGATING THERAPEUTIC STRATEGIES TO TARGET METABOLIC VULNERABILITIES OF NSCLC TUMORS WITH MUTANT KEAP1 GENE, Pranavi Koppula
Dissertations and Theses (Open Access)

PDF

DECIPHERING THE ROLE OF HSP110 CHAPERONES IN DISEASES OF PROTEIN MISFOLDING, Unekwu M. Yakubu
Dissertations and Theses (Open Access)

PDF

MODULATION OF THE RECEPTOR GATING MECHANISM AND ALLOSTERIC COMMUNICATION IN IONOTROPIC GLUTAMATE RECEPTORS, Nabina Paudyal, Nabina Paudyal
Dissertations and Theses (Open Access)

PDF

Agonist-Induced Conformational Changes in the NMDA Receptor, Ryan Durham, Ryan Durham
Dissertations and Theses (Open Access)

PDF

NPSD4: A NEW PLAYER IN SUMO-DEPENDENT DNA REPAIR, Erin Atkinson
Dissertations and Theses (Open Access)

PDF

Unveiling global roles of G-quadruplexes and G4-22 in human genetics, Ruth Barros De Paula
Dissertations and Theses (Open Access)

PDF

The Functional Analysis of a Major Tyrosine Phosphorylation Site on Actin, Amelie Simone Cordelia Albrecht
Dissertations and Theses (Open Access)

PDF

UNDERSTANDING THE ROLE OF ARGLU1 IN INTERFERON SIGNALING ACTIVATION IN BREAST CANCER, Phuoc Nguyen
Dissertations and Theses (Open Access)

PDF

DISCOVERY OF NOVEL UBIQUITIN- AND METHYLATION-DEPENDENT INTERACTIONS USING PROTEIN DOMAIN MICROARRAYS, Jianji Chen
Dissertations and Theses (Open Access)

PDF

2020

SINE OCULIS HOMEOBOX HOMOLOG 1 (SIX1) PLAYS A CRITICAL ROLE IN THE PROGRESSION OF PULMONARY FIBROSIS., Cory Wilson
Dissertations and Theses (Open Access)

PDF

Calcium Dyshomeostasis in Neurodegeneration, Nicholas Emanuel Karagas
Dissertations and Theses (Open Access)

PDF

DEVELOPMENT OF COMPUTATIONAL TOOLS TO TARGET MICRORNA, Luo Song
Dissertations and Theses (Open Access)

PDF

A CONTEXT-FORWARD IN VIVO FUNCTIONAL GENOMICS PLATFORM FOR TARGET DISCOVERY AND ESTABLISHING VULNERABILITY CONTEXT IN PANCREATIC CANCER, Johnathon Rose, Johnathon Lynn Rose
Dissertations and Theses (Open Access)

PDF

IONIC MECHANISM OF LYSOSOMAL FUNCTION AND CELL METABOLISM, Jian Xiong
Dissertations and Theses (Open Access)

PDF

p53 drives a transcriptional program that elicits a non-cell-autonomous response and alters cell state in vivo, Sydney Moyer
Dissertations and Theses (Open Access)

PDF

IDENTIFICATION OF TRIM24 DOMAIN ESSENTIALITY IN PRIMARY TRIM24COE CARCINOSARCOMA CELL LINES, Cem Dede
Dissertations and Theses (Open Access)

PDF

Elevated cochlear adenosine causes hearing loss via ADORA2B signaling, Jeanne Manalo
Dissertations and Theses (Open Access)

PDF

METHODS TO INVESTIGATE HYPERTHERMIA INDUCED BY TUMOR TREATING FIELDS, Ruchi Singh
Dissertations and Theses (Open Access)

PDF

Investigating the role of Quaking in antigen uptake and cross-presentation by dendritic cells, Yating Li
Dissertations and Theses (Open Access)

PDF

Artificial intron technology to generate conditional knock-out mice, Amber N. Thomas-Gordon
Dissertations and Theses (Open Access)

PDF

LOSS OF CASPASE-8 FUNCTION IN COMBINATION WITH SMAC MIMETIC TREATMENT SENSITIZES HEAD AND NECK SQUAMOUS CARCINOMA TO RADIATION THROUGH INDUCTION OF NECROPTOSIS., Burak Uzunparmak
Dissertations and Theses (Open Access)

PDF

ALTERNATIVE POLYADENYLATION MODULATES EXPRESSION OF PRO-FIBROTIC PROTEINS AND CONTRIBUTES TO LUNG FIBROSIS, Junsuk Ko
Dissertations and Theses (Open Access)

PDF

EFFECTS OF PENFLURIDOL ON INTEGRIN-FAK SIGNALING AND TUMOR CELL KILLING IN COMBINATION WITH ONCOLYTIC HSV IN GLIOBLASTOMA, Mitra Nair
Dissertations and Theses (Open Access)

PDF

10th Annual Postdoctoral Science Symposium, University of Texas MD Anderson Cancer Center PostDoctoral Association
MD Anderson Cancer Center Postdoctoral Association Annual Postdoctoral Science Symposium Abstracts

PDF

2019

A NOVEL SWITCH-LIKE FUNCTION OF DELTA-CATENIN IN DENDRITE DEVELOPMENT, Ryan Baumert
Dissertations and Theses (Open Access)

PDF

THE ROLE OF MEMBRANE DOMAINS IN PROTEIN AND LIPID SORTING DURING ENDOCYTIC TRAFFIC, Blanca B. Diaz-Rohrer
Dissertations and Theses (Open Access)

PDF

9th Annual Postdoctoral Science Symposium, University of Texas MD Anderson Cancer Center PostDoctoral Association
MD Anderson Cancer Center Postdoctoral Association Annual Postdoctoral Science Symposium Abstracts

PDF

DEUBIQUITINATING ENZYMES PROMOTE CANCER PROGRESSION AND METASTASIS VIA REGULATING PROTEIN STABILITY, Zhenna Xiao
Dissertations and Theses (Open Access)

PDF

INVESTIGATIONS OF THE STRUCTURE-FUNCTION RELATIONSHIP IN KAINATE RECEPTORS USING FÖRSTER RESONANCE ENERGY TRANSFER, Douglas Litwin
Dissertations and Theses (Open Access)

PDF

OBSCURIN MEDIATES ANKYRIN COMPLEX FORMATION IN THE HEART, Janani Subramaniam
Dissertations and Theses (Open Access)

PDF

IPSC BASED GENE CORRECTION AND DISEASE MODEL OF A NEW CLASS OF LGMD DUE TO POGLUT1 MUTATION, Jose Ortiz-Vitali
Dissertations and Theses (Open Access)

PDF

THE GSK-3β-FBXL21 AXIS REGULATES TCAP VIA UBIQUITIN-MEDIATED PROTEASOMAL PATHWAY IN THE CYTOPLASM, Jiah Yang
Dissertations and Theses (Open Access)

PDF

DISSECTING THE ROLES OF HUMAN SMC COMPLEXES IN TRANSCRIPTION REGULATION AND CHROMATIN ORGANIZATION, Ruoyu Wang
Dissertations and Theses (Open Access)

PDF

THE ROLE OF GENE EXPRESSION NOISE IN MAMMALIAN CELL SURVIVAL, Kevin Farquhar
Dissertations and Theses (Open Access)

PDF

Hsp70-mediated regulation of Hsf1 transcriptional activity in Saccharomyces cerevisiae, Sara Peffer
Dissertations and Theses (Open Access)

PDF

AN OXANTHROQUINONE DERIVATIVE DISRUPTS RAS PLASMA MEMBRANE LOCALIZATION AND FUNCTION BY INHIBITION OF ACYLPEPTIDE HYDROLASE AND PERTURBATION OF SPHINGOMYELIN METABOLISM, Lingxiao Tan
Dissertations and Theses (Open Access)

PDF

Development of a High-Throughput System for Screening of Anti-Prion Molecules, Katherine Do
Dissertations and Theses (Open Access)

PDF

Thiol-based Misfolding: Linking Redox Balance to Cytosolic Proteostasis, Ford Amy
Dissertations and Theses (Open Access)

PDF

Data collection curated with an application ontology describes the methods and results upon performing an ex-vivo voltage-clamp assay on outer hair cells of the mammalian cochlea, Brenda Farrell, Jason Bengtson
BCM Research Data

2018

ROLE OF P300 ZZ DOMAIN IN CHROMATIN ASSOCIATION AND HISTONE ACETYLATION, Yongming Xue
Dissertations and Theses (Open Access)

PDF

A ROLE FOR EPAC1 AND EPAC2 IN NOCICEPTOR HYPEREXCITABILITY AND CHRONIC PAIN AFTER SPINAL CORD INJURY, Samantha Berkey
Dissertations and Theses (Open Access)

PDF

8th Annual Postdoctoral Science Symposium, University of Texas MD Anderson Cancer Center PostDoctoral Association
MD Anderson Cancer Center Postdoctoral Association Annual Postdoctoral Science Symposium Abstracts

PDF

An expanded toolkit for gene tagging based on MiMIC and scarless CRISPR tagging in, David Li-Kroeger, Oguz Kanca, Pei-Tseng Lee, Sierra Cowan, Michael T Lee, Manish Jaiswal, Jose Luis Salazar, Yuchun He, Zhongyuan Zuo, Hugo J Bellen
BCM Faculty Publications

PDF

Characterizing the recognition motif and novel substrates of CARM1, Sitaram gayatri
Dissertations and Theses (Open Access)

PDF

Nanoscale Organization of the Small GTPase Rac1, Kelsey Maxwell
Dissertations and Theses (Open Access)

PDF

The Regulation of DNA Methylation in Mammalian Development and Cancer, Nicolas Veland
Dissertations and Theses (Open Access)

PDF

EVOLUTION VIA GENE DUPLICATION AND ALTERNATIVE SPLICING IN THE EUKARYOTIC SKI7 AND HBS1 GENES, Alexandra Marshall
Dissertations and Theses (Open Access)

PDF

BIOLOGICAL CLOCKS, INFLAMMATION, AND MULTIORGAN DAMAGE IN SICKLE CELL DISEASE, Morayo Adebiyi
Dissertations and Theses (Open Access)

PDF

DECIPHERING THE ROLES OF ΔNP63 IN REGULATING EPITHELIAL TO MESENCHYMAL TRANSITION, CANCER PROGRESSION AND METASTASIS, Ngoc Bui
Dissertations and Theses (Open Access)

PDF

Functional Similarity of PRD-Containing Virulence Regulators in Bacillus anthracis, Malik Raynor
Dissertations and Theses (Open Access)

PDF

INVESTIGATING THE IMPACT OF INTRAGENIC DNA METHYLATION ON GENE EXPRESSION, AND THE CLINICAL IMPLICATIONS ON TUMOR CELLS AND ASSOCIATED STROMA, Michael McGuire
Dissertations and Theses (Open Access)

PDF

Discovery and effects of pharmacological inhibition of the E3 ligase Skp2 by small molecule protein-protein interaction disruptors, John K. Morrow
Dissertations and Theses (Open Access)

PDF

2017

ENDOCYTIC TRAFFICKING OF THE AMYLOID PRECURSOR PROTEIN IN RAT CORTICAL NEURONS, sahily reyes
Dissertations and Theses (Open Access)

PDF

CHARACTERIZATION OF NOTCH1 AND PI3K-PTEN-AKT/mTOR PATHWAY INTERACTION IN HEAD AND NECK SQUAMOUS CELL CARCINOMA, Kyriante' Henry
Dissertations and Theses (Open Access)

PDF

The functions of SETD5 and miR-221 in embryonic stem cell differentiation, Tsai-Yu Chen
Dissertations and Theses (Open Access)

PDF

INSIGHTS INTO THE THERAPEUTIC POTENTIAL OF SALT INDUCIBLE KINASE 1: A NOVEL MECHANISM OF METABOLIC CONTROL, Randi Fitzgibbon
Dissertations and Theses (Open Access)

PDF

Gcn5 Impacts FGF Signaling At Multiple Levels And Activates C-Myc Target Genes During Early Differentiation Of Embryoid Bodies, Li Wang
Dissertations and Theses (Open Access)

PDF

STRUCTURAL AND FUNCTIONAL EFFECT OF PHOSPHORYLATION ON AMPA RECEPTORS, Caitlin E. Nurik
Dissertations and Theses (Open Access)

PDF

Preclinical Development of Therapeutic Strategies Against Triple-Negative and Inflammatory Breast Cancer, Angie M. Torres-Adorno
Dissertations and Theses (Open Access)

PDF

INVESTIGATING THE ROLE OF PRMT1 AND ARGININE METHYLATION OF HSP70 IN HUMAN PANCREATIC CANCER, Liang Wang
Dissertations and Theses (Open Access)

PDF

LBPI: A WEB INTERFACE FOR THE IDENTIFICATION OF ALLOSTERIC LIGAND BINDING SITES, Nabina Paudyal
Dissertations and Theses (Open Access)

PDF

A PRECLINICAL STUDY OF RADIATION-INDUCED LUNG TOXICITY WHEN IRRADIATING IN A STRONG MAGNETIC FIELD, Ashley E. Rubinstein
Dissertations and Theses (Open Access)

LBPI: A WEB INTERFACE FOR THE IDENTIFICATION OF ALLOSTERIC LIGAND BINDING SITES, Nabina Paudyal
Dissertations and Theses (Open Access)

PHOPSPHORYLATION AND UBIQUITIN MODIFICATION AT DNA DAMAGE SITES IN RESPONSE TO DOUBLE-STRAND BREAKS, Atanu Paul
Dissertations and Theses (Open Access)

PDF

UNDERSTANDING THE MECHANISM OF GENOMIC INSTABILITY DURING REPLICATIVE AGING IN BUDDING YEAST, Sangita Pal
Dissertations and Theses (Open Access)

PDF

ANALYSIS OF THE BIOCHEMICAL AND CELLULAR ACTIVITIES OF SUBSTRATE BINDING BY THE MOLECULAR CHAPERONE HSP110/SSE1, Veronica M. Garcia
Dissertations and Theses (Open Access)

PDF

NON-CODING RNAS IDENTIFY THE INTRINSIC MOLECULAR SUBTYPES OF MUSCLE-INVASIVE BLADDER CANCER, Andrea E. Ochoa
Dissertations and Theses (Open Access)

PDF

ROLE AND REGULATION OF SPHINGOSINE 1-PHOSPHATE IN ERYTHROCYTE, Kaiqi Sun
Dissertations and Theses (Open Access)

PDF

THE ROLE OF ADENOSINE SIGNALING IN MATURE ERYTHROCYTES AND ERYTHROID PROGENITORS, Hong Liu
Dissertations and Theses (Open Access)

PDF

FRET-Based Investigations of the Structure-Function Relationships in the NMDA Receptor, Drew M. Dolino
Dissertations and Theses (Open Access)

PDF

A rare case of erythema elevatum diutinum presenting as diffuse neuropathy., G H. Nguyen, E L. Guo, D Norris
BCM Faculty Publications

PDF

2016

THE ROLE OF PHOSPHORYLATION IN PAM2 MOTIF-CONTAINING PROTEINS MEDIATED MESSENGER RNA DEADENYLATION, KAI-LIEH HUANG
Dissertations and Theses (Open Access)

PDF

Consensus Paper: Cerebellar Development., K Leto, M Arancillo, EBE Becker, A Chiang, et al.
BCM Faculty Publications

PDF

Characterization of Vesicular Monoamine Transporter 2 and its role in Parkinson's Disease Pathogenesis using Drosophila, Antonio Joel Tito Jr., Sheng Zhang
Dissertations and Theses (Open Access)

PDF

Role of phosphorylation in the regulation of PRMT5, Alexsandra B. Espejo
Dissertations and Theses (Open Access)

PDF

¬¬DEFINE THE EPIGENETIC PROFILES AND SUBTYPE-SPECIFIC GENES OF BREAST CANCER, Wenqian Li
Dissertations and Theses (Open Access)

PDF

CIRCUMVENTING CISPLATIN RESISTANCE IN OVARIAN CANCERS THROUGH REACTIVATION OF p53 BY NON-CROSS-RESISTANT PLATINUM ANALOGS, Michelle Martinez-Rivera
Dissertations and Theses (Open Access)

PDF

DEFINING THE FUNCTIONS OF USP22 AND USP44 IN REGULATION OF H2BUB1 LEVELS, xianjiang Lan
Dissertations and Theses (Open Access)

PDF

INVESTIGATING THE ROLES OF ΔNP63 AS A SUPPRESSOR OF MIGRATION, INVASION, AND METASTASIS, Ramon E. Flores Gonzalez
Dissertations and Theses (Open Access)

PDF

PREECLAMPSIA: THE ROLES OF ACUTE INFLAMMATION AND INTRAUTERINE STRESS, Nicholas Parchim
Dissertations and Theses (Open Access)

PDF

CLL METABOLISM IS REGULATED BY PROGNOSTIC FACTORS, MODULATED BY STROMA AND ABROGATED BY PI3K INHIBITION, Hima Vangapandu
Dissertations and Theses (Open Access)

PDF

THE ROLES OF MALT1 IN NF-κB ACTIVATION AND SOLID TUMOR PROGRESSION, Deng Pan
Dissertations and Theses (Open Access)

PDF

MECHANISMS OF REGULATION OF TAU IRES MEDIATED TRANSLATION, Niza Nemkul
Dissertations and Theses (Open Access)

PDF

Developing and using methyl-specific antibodies to study the biological roles of arginine methylation, Vidyasiri Vemulapalli
Dissertations and Theses (Open Access)

PDF

Comparison of interactive voice response (IVR) with paper administration of instruments to assess functional status, sexual function, and quality of life in elderly men., RC Rosen, AJ Stephens-Shields, GR Cunningham, D Cifelli, D Cella, JT Farrar, E Barrett-Connor, CE Lewis, M Pahor, X Hou, PJ Snyder
BCM Faculty Publications

PDF

Explicit Time Deficit in Schizophrenia: Systematic Review and Meta-Analysis Indicate It Is Primary and Not Domain Specific., V Ciullo, G Spalletta, C Caltagirone, RE Jorge, F Piras
BCM Faculty Publications

PDF

Is Whole-Exome Sequencing an Ethically Disruptive Technology? Perspectives of Pediatric Oncologists and Parents of Pediatric Patients With Solid Tumors., Laurence B McCullough, Melody J Slashinski, Amy L McGuire, Richard L Street, Christine M Eng, Richard A Gibbs, D William Parsons, Sharon E Plon
BCM Faculty Publications

PDF

Identification of an Association of TNFAIP3 Polymorphisms With Matrix Metalloproteinase Expression in Fibroblasts in an Integrative Study of Systemic Sclerosis-Associated Genetic and Environmental Factors.*, Peng Wei, Yang Yang, Xinjian Guo, Nainan Hei, Syeling Lai, Shervin Assassi, Mengyuan Liu, Filemon Tan, Xiaodong Zhou
BCM Faculty Publications

PDF

CT-based Structural Rigidity Analysis Is More Accurate Than Mirels Scoring for Fracture Prediction in Metastatic Femoral Lesions., TA Damron, A Nazarian, V Entezari, C Brown, W Grant, N Calderon, et al.
BCM Faculty Publications

PDF

Glial Contributions to Neural Function and Disease., MN Rasband
BCM Faculty Publications

PDF

Eosinophilic Esophagitis in Children and Its Relationship with Parental Allergies: Texas Children's Hospital Experience., G Hiremath, D Byramji, A Pacheco, G Constantine, C Davis, R Shulman, A Olive
BCM Faculty Publications

PDF

Efficacy of Psychosocial Interventions in Inducing and Maintaining Alcohol Abstinence in Patients With Chronic Liver Disease: A Systematic Review., A Khan, A Tansel, DL White, WT Kayani, WT Bano, J Lindsay, HB El-Serag, F Kanwal
BCM Faculty Publications

PDF

Early rescue of interneuron disease trajectory in developmental epilepsies., MS Siehr, JL Noebels
BCM Faculty Publications

PDF

Effect of Two-Year Caloric Restriction on Bone Metabolism and Bone Mineral Density in Non-Obese Younger Adults: A Randomized Clinical Trial., DT Villareal, L Fontana, SK Das, et al.
BCM Faculty Publications

PDF

Local Corticotropin Releasing Hormone (CRH) Signals To Its Receptor CRHR1 During Postnatal Development of the Mouse Olfactory Bulb., Isabella Garcia, Paramjit K Bhullar, Burak Tepe, Joshua Ortiz-Guzman, Longwen Huang, Alexander M Herman, Lesley Chaboub, Benjamin Deneen, Nicholas J Justice, Benjamin R Arenkiel
BCM Faculty Publications

PDF

Identification of a Novel Gene on 10q22.1 Causing Autosomal Dominant Retinitis Pigmentosa (adRP)., Stephen P Daiger, Lori S Sullivan, Sara J Bowne, Daniel C Koboldt, Susan H Blanton, Dianna K Wheaton, Cheryl E Avery, Elizabeth D Cadena, Robert K Koenekoop, Robert S Fulton, Richard K Wilson, George M Weinstock, Richard A Lewis, David G Birch
BCM Faculty Publications

PDF

2015

PREVENTING THYMUS INVOLUTION IN K5.CYCLIN D1 TRANSGENIC MICE SUSTAINS THE NAÏVE T CELL COMPARTMENT WITH AGE, Michelle L. Bolner
Dissertations and Theses (Open Access)

PDF

Normal Glycolytic Enzyme Activity is Critical for Hypoxia Inducible Factor-1a Activity and Provides Novel Targets for Inhibiting Tumor Growth, Geoffrey Grandjean PhD
Dissertations and Theses (Open Access)

PDF

THE TUMOR SUPPRESSOR NOTCH INHIBITS HEAD AND NECK SQUAMOUS CELL CARCINOMA (HNSCC) TUMOR GROWTH AND PROGRESSION BY MODULATING PROTO-ONCOGENES AXL AND CTNNAL1 (α-CATULIN), Shhyam Moorthy, Shhyam Moorthy
Dissertations and Theses (Open Access)

PDF

MOLECULAR REGULATION OF VASCULAR CALCIFICATION IN MURINE MODELS OF ATHEROSCLEROSIS, Shanshan Gao
Dissertations and Theses (Open Access)

PDF

Histone H3 K4 methylation regulates the Spindle Assembly Checkpoint through direct binding of multiple checkpoint components and Cdc20, Andria C. Schibler
Dissertations and Theses (Open Access)

PDF

GATING MECHANISMS OF THE CANONICAL TRP CHANNEL ISOFORM TRPC4, Dhananjay P. Thakur
Dissertations and Theses (Open Access)

PDF

DIRECT REGULATION OF APOPTOSIS BY LINEAR UBIQUTIN CHAIN ASSEMBLY COMPLEX (LUBAC) AND FEEDBACK REGULATION OF LUBAC FUNCTION BY CASPASES, Donghyun Joo
Dissertations and Theses (Open Access)

PDF

Structure and Composition of Postsynaptic Densities, Madeline Farley
Dissertations and Theses (Open Access)

PDF

COMPUTATIONAL MODELING OF RNA-SMALL MOLECULE AND RNA-PROTEIN INTERACTIONS, Lu Chen
Dissertations and Theses (Open Access)

PDF

Investigating the Interaction of AURKA and UBE2C in Colorectal Cancer Cells, Apurva M. Hegde
Dissertations and Theses (Open Access)

PDF

Prophylactic Cranial Irradiation Reduces the Incidence of Brain Metastasis in a Mouse Model of Metastatic Breast Cancer, Daniel L. Smith
Dissertations and Theses (Open Access)

PDF

The Structural Mechanism of Allosteric Modulation of the NMDA Receptor: A Balance of Tensions, Rita E. Sirrieh
Dissertations and Theses (Open Access)

PDF

SELECTION METHODS FOR GENETICALLY-MODIFIED T CELLS: IN SUPPORT OF TRANSLATIONAL THERAPY, David Rushworth
Dissertations and Theses (Open Access)

PDF

DNA POLYMERASE θ (POLQ) AND THE CELLULAR DEFENSE AGAINST DNA DAMAGE, Matthew J. Yousefzadeh
Dissertations and Theses (Open Access)

PDF

Regulation of Cell Adhesion by the FERM Proteins, PTPN14 and Merlin, Patty Dimarco Hewitt
Dissertations and Theses (Open Access)

PDF

Investigating the roles of p63 and p73 isoforms to therapeutically treat p53-altered cancers, Avinashnarayan Venkatanarayan
Dissertations and Theses (Open Access)

PDF

DEVELOPMENTAL ORIGINS OF RENAL CONNECTING TUBULE AND COLLECTING DUCT: ROLE OF AQP2+ PROGENITOR CELLS, Lihe Chen
Dissertations and Theses (Open Access)

PDF

THE EFFECT OF ACTIVATION INDUCED CYTIDINE DEAMINASE PHOSPHORYLATION AND HERPES VIRUS URACIL DNA GLYCOSYLASE ON ANTIBODY DIVERSIFICATION, Marc Macaluso
Dissertations and Theses (Open Access)

PDF

MEASURING SINGLE CELL RESPONSES TO LAPATINIB IN A HETEROGENEOUS POPULATION, Preety Priya
Dissertations and Theses (Open Access)

PDF

INVESTIGATION OF THE ROLE OF THE SCAFFOLD PROTEIN SHC IN ERK SIGNALING, kin man suen
Dissertations and Theses (Open Access)

PDF

2014

Novel Posttranslational Modification in LKB1 Activation and Function, Szu-Wei Lee
Dissertations and Theses (Open Access)

PDF

p120-catenin regulates REST and CoREST, and modulates mouse embryonic stem cell differentiation, moonsup lee
Dissertations and Theses (Open Access)

PDF

Swarna Ramaswamy_Thesis, Swarna S. Ramaswamy
Dissertations and Theses (Open Access)

PDF

JAB1 NEGATIVELY REGULATES PTEN AND PROMOTES RESISTANCE TO TRASTUZUMAB IN HER2-POSITIVE BREAST CANCER, Thuy T. Vu
Dissertations and Theses (Open Access)

PDF

Large-scale Identification of Chemically Induced Mutations in Drosophila melanogaster., Nele A Haelterman, Lichun Jiang, Yumei Li, Vafa Bayat, Hector Sandoval, Berrak Ugur, Kai Li Tan, Ke Zhang, Danqing Bei, Bo Xiong, Wu-Lin Charng, Theodore Busby, Adeel Jawaid, Gabriela David, Manish Jaiswal, Koen J T Venken, Shinya Yamamoto, Rui Chen, Hugo J Bellen
BCM Faculty Publications

PDF

ROLES FOR B-Raf KINASE IN THE SPECIFIC REGULATION OF α4β1 INTEGRIN IN T CELLS, Wells S. Brown
Dissertations and Theses (Open Access)

PDF

ENERGY STRESS CAUSES CHAPERONES TO ASSEMBLE INTO CYTOPLASMIC COMPLEXES, Kimberly J. Cope
Dissertations and Theses (Open Access)

PDF

Mapping the Human Vasculature by In Vivo Phage Display, Julianna Bronk
Dissertations and Theses (Open Access)

PDF

EGFR Modulates MicroRNA Maturation In Response To Hypoxia Through Phosphorylation Of Argonaute2, Jia Shen
Dissertations and Theses (Open Access)

PDF

PI3K- and mTOR-dependent mechanisms of lapatinib resistance and resulting therapeutic opportunities, Samuel Brady
Dissertations and Theses (Open Access)

PDF

ANGIOMOTIN IS A NOVEL CADHERIN-11 INTERACTING PROTEIN THAT MEDIATES MIGRATION IN PROSTATE CANCER CELLS, Angelica Ortiz
Dissertations and Theses (Open Access)

PDF

Chemical mutagens, transposons, and transgenes to interrogate gene function in Drosophila melanogaster., Koen J T Venken, Hugo J Bellen
BCM Faculty Publications

CHARACTERIZATION OF FTSA-FTSN INTERACTION DURING ESCHERICHIA COLI CELL DIVISION, kimberly.busiek@gmail.com K. Busiek
Dissertations and Theses (Open Access)

PDF

DIABETES AND OBESITY INDUCE TRANSCRIPTOMIC AND METABOLOMIC CHANGES ENHANCING PANCREATIC CANCER AGGRESSIVENESS, Guermarie Velázquez Torres
Dissertations and Theses (Open Access)

PDF

The regulation of microRNA biogenesis by ribosome-interacting proteins, Brian Pickering
Dissertations and Theses (Open Access)

PDF

Functional Analysis of Cytosolic Hsp70 Nucleotide Exchange Factor Networks in Yeast, Jennifer Lynn Abrams
Dissertations and Theses (Open Access)

PDF

2013

Characterization of the RNA binding and RNA degrading subunits of the eukaryotic exosome, Borislava Tsanova
Dissertations and Theses (Open Access)

PDF

THE STAPHYLOCOCCUS PSEUDINTERMEDIUS ADHESIN SPSD CONTAINS A CENTRAL FIBRONECTIN-BINDING DOMAIN, Andrea S. Bordt
Dissertations and Theses (Open Access)

PDF

A NOVEL CARDIAC FUNCTION OF SUMO2/3 AND SENP5 DEPENDENT PATHWAY AND ITS PHYSIOLOGICAL IMPACT ON CONGESTIVE CARDIOMYOPATHY, Eun Young Kim
Dissertations and Theses (Open Access)

PDF

Characterization of Jak, STAT, and Src interactions in Head and Neck Squamous Cell Carcinoma, Reshma Jaseja, Reshma Jaseja
Dissertations and Theses (Open Access)

PDF

STUDYING AGGREGATE FORMATION BY AMYOTROPHIC LATERAL SCLEROSIS-ASSOCIATED MUTANT SOD1 PROTEIN IN DROSOPHILA MODEL, Michael McCarthy
Dissertations and Theses (Open Access)

PDF

CONFORMATIONAL DYNAMICS OF K-RAS AND H-RAS PROTEINS: IS THERE FUNCTIONAL SPECIFICITY AT THE CATALYTIC DOMAIN?, NANDINI RAMBAHAL
Dissertations and Theses (Open Access)

PDF

INTERACTION BETWEEN BRK AND HER2 IN BREAST CANCER, Midan Ai
Dissertations and Theses (Open Access)

PDF

INTERACTION OF BACILLUS ANTHRACIS EXOSPORIUM PROTEIN BCLA WITH COMPLEMENT FACTOR H AND SPORE PERSISTENCE IN THE LUNG, Sarah A. Jenkins
Dissertations and Theses (Open Access)

PDF

GENOME-WIDE PROFILING UNVEILS CRITICIAL FUNCTIONS OF p53 IN HUMAN EMBRYONIC STEM CELLS, Kadir C. Akdemir
Dissertations and Theses (Open Access)

PDF

Mechanisms Underlying the Heterogeneous Sensitivities of Cancer Cells to Proteasome Inhibitors, Matthew C. White
Dissertations and Theses (Open Access)

PDF

Structure-function analysis of human Integrator subunit-4, Anupama Sataluri
Dissertations and Theses (Open Access)

PDF

2012

FANCM AND FAAP24 MAINTAIN GENOMIC STABILITY THROUGH COOPERATIVE AND UNIQUE FUNCTIONS, Yucai Wang
Dissertations and Theses (Open Access)

PDF

TET1: A UNIQUE DNA DEMETHYLASE FOR MAINTENANCE OF DNA METHYLATION PATTERN, CHUNLEI JIN
Dissertations and Theses (Open Access)

PDF

Functional Analysis of Drosophila Integrator Complex in snRNA 3' End Processing, Jiandong Chen
Dissertations and Theses (Open Access)

PDF

Differential Activity of the KRAS Oncogene by Method of Activation: Implications for Signaling and Therapeutic Intervention, Nathan Ihle
Dissertations and Theses (Open Access)

PDF

BIOCHEMICAL CHARACTERIZATION OF BINDING PARTNERS OF TWO HSP70 CO-CHAPERONES IN SACCHAROMYCES CEREVISIAE, Jacob Verghese
Dissertations and Theses (Open Access)

PDF

The Role of the Arched Helicases in Exosome-Mediated Function, A. Alejandra Klauer
Dissertations and Theses (Open Access)

PDF

A STUDY ON THE FUNCTION OF 14-3-3SIGMA IN REGULATING CANCER ENERGY METABOLISM, Liem M. Phan, Liem M. Phan
Dissertations and Theses (Open Access)

PDF

TRIM24-REGULATED ESTROGEN RESPONSE IS DEPENDENT ON SPECIFIC HISTONE MODIFICATIONS IN BREAST CANCER CELLS, Teresa T. Yiu
Dissertations and Theses (Open Access)

PDF

REGULATION OF TOXIN SYNTHESIS BY CLOSTRIDIUM DIFFICILE, Charles Darkoh
Dissertations and Theses (Open Access)

PDF

Syntaxin 6- and microtubule- mediated intracellular trafficking contributes to Golgi and nuclear translocation of EGFR, Yi Du
Dissertations and Theses (Open Access)

PDF

DETERMINING THE GENOTYPE-PHENOTYPE CONNECTION IN SYNTHETIC INDUCIBLE GENE EXPRESSION SYSTEMS, Rhys M. Adams
Dissertations and Theses (Open Access)

PDF

Regulation of Protein Degradation in the Heart by AMP-Activated Protein Kinase, Kedryn K. Baskin, Kedryn K. Baskin
Dissertations and Theses (Open Access)

PDF

CHEMOSENSITIZATION OF HEPATOCELLULAR CARCINOMA TO GEMCITABINE BY NON-INVASIVE RADIOFREQUENCY FIELD-INDUCED HYPERTHERMIA, Mustafa Raoof
Dissertations and Theses (Open Access)

PDF

Regulation of Protein Degradation in the Heart by AMP-Activated Protein Kinase, Kedryn K. Baskin
Dissertations and Theses (Open Access)

PDF

Increased geranylgeranylated K-Ras contributes to antineoplastic effects of farnesyltransferase inhibitors., Mandy A. Hall
Dissertations and Theses (Open Access)

PDF

2011

CONFORMATIONAL CHANGES IN THE EXTRACELLULAR DOMAIN OF GLUTAMATE RECEPTORS, Anu Rambhadran
Dissertations and Theses (Open Access)

PDF

DEFINITION OF THE LANDSCAPE OF CHROMATIN STRUCTURE AT THE FRATAXIN GENE IN FRIEDREICH’S ATAXIA, Eunah Kim
Dissertations and Theses (Open Access)

PDF

THE ROLE OF RECEPTOR TYROSINE KINASE AXL IN PANCREATIC DUCTAL ADENOCARCINOMA AND ITS REGULATION BY HEMATOPOIETIC PROGENITOR KINASE 1, Xianzhou Song
Dissertations and Theses (Open Access)

PDF

Uptake And Metabolism Of 5’-AMP In The Erythrocyte Play Key Roles In The 5’-AMP Induced Model Of Deep Hypometabolism, Isadora Daniels
Dissertations and Theses (Open Access)

PDF

Mechanisms of Adenovirus-Mediated Autophagy, Erin White
Dissertations and Theses (Open Access)

PDF

DEVELOPMENTAL DEREGULATION AND TUMORIGENESIS INHIBITION IN 14-3-3ZETA KNOCKOUT MOUSE, Jun Yang
Dissertations and Theses (Open Access)

PDF

Significance of Increased Tissue Transglutaminase in Hormone Refractory Prostate Cancer, Amy L. Han
Dissertations and Theses (Open Access)

PDF

DOWNREGULATION OF PAX2 SUPPRESSES OVARIAN CANCER CELL GROWTH, huijuan song
Dissertations and Theses (Open Access)

PDF

The Role of Cancer-Associated Fibroblasts in Lung Tumorigenesis, Jonathon D. Roybal
Dissertations and Theses (Open Access)

PDF

ECHOGENIC LIPOSOMES FOR NITRIC OXIDE DELIVERY AND BREAST CANCER TREATMENT, Soo Yeon LEE Female
Dissertations and Theses (Open Access)

PDF

The Role of the Androgen Receptor Cofactor p44/WDR77 in Astrocyte Activation, Bryce H. Vincent
Dissertations and Theses (Open Access)

PDF

Dissecting the Interaction between p53 and TRIM24, Aundrietta D. Duncan
Dissertations and Theses (Open Access)

PDF

A NOVEL FUNCTION FOR AURORA B KINASE IN THE REGULATION OF P53 BY PHOSPHORYLATION, chris p. gully
Dissertations and Theses (Open Access)

PDF

The Role of IL-6 in Adenosine-Mediated Pulmonary Fibrosis, Mesias Pedroza
Dissertations and Theses (Open Access)

PDF

Regulation of Set1-mediated methylation of Dam1, John A. Latham
Dissertations and Theses (Open Access)

PDF

Molecular mechanism by which the Escherichia coli nucleoid occlusion factor, SlmA, keeps cytokinesis in check, Nam K. Tonthat
Dissertations and Theses (Open Access)

PDF

THE ROLE AND MECHANISM OF THE HOMEOBOX GENE DLX4 IN TRANSFORMING GROWTH FACTOR-B RESISTANCE IN CANCER, Bon Q. Trinh
Dissertations and Theses (Open Access)

PDF

Expression and Regulation of Human Cytochrome P450 4F Isoforms in Tissue Samples and Under TNF-Alpha Challenges, Jordan C. Bell
Dissertations and Theses (Open Access)

PDF

Mechanisms regulating the p120-catenin/Kaiso pathway, JI YEON HONG
Dissertations and Theses (Open Access)

PDF

2010

AGROBACTERIUM VIRB10 CONTRIBUTIONS TO TYPE IV SUBSTRATE SECRETION, T-PILUS BIOGENESIS, AND OUTER MEMBRANE PORE FORMATION, Isaac Garza
Dissertations and Theses (Open Access)

PDF

ELUCIDATING FUNCTIONAL ROLES FOR MYOGENIN IN ADULT SKELETAL MUSCLE METABOLISM, EXERCISE CAPACITY, AND REGENERATION, Jesse Flynn
Dissertations and Theses (Open Access)

PDF

Dynamic Remodeling of the Stressed Heart: Role of Protein Degradation Pathways, Deborah Vela
Dissertations and Theses (Open Access)

PDF

Role and Regulation of EphA2 in Pancreatic Cancer, Pavel A. Levin
Dissertations and Theses (Open Access)

PDF

ARTEMIS INTERACTS WITH THE CUL4A UBIQUITIN E3 LIGASE COMPLEX AND REGULATES THE CELL CYCLE PROGRESSION, Yiyi Yan
Dissertations and Theses (Open Access)

PDF

Specific, Reversible Cytostatic Protection of Normal Cells Against Negative Effects of Chemotherapy, Benjamin B. Mull
Dissertations and Theses (Open Access)

PDF

Developmental Changes in the Structure and Composition of the Postsynaptic Density, Matthew T. Swulius
Dissertations and Theses (Open Access)

PDF

THE UBIQUITIN LIGASE UBE4B IS REQUIRED FOR EFFICIENT EPIDERMAL GROWTH FACTOR RECEPTOR DEGRADATION, Natalie Sirisaengtaksin
Dissertations and Theses (Open Access)

PDF

AMPA RECEPTOR ALLOSTERISM: MEASUREMENT OF THE CONFORMATIONAL CHANGES IN THE LIGAND BINDING DOMAIN OF A FUNCTIONAL RECEPTOR, Jennifer Gonzalez-McGehee
Dissertations and Theses (Open Access)

PDF

Host-pathogen interactions of secreted and surface Staphylococcus aureus factors, Vanessa Vazquez
Dissertations and Theses (Open Access)

PDF

A NEW TUMOR SUPPRESSOR GENE CANDIDATE REGULATED BY THE NON-CODING RNA PCA3 IN HUMAN PROSTATE CANCER, Alessandro K. Lee
Dissertations and Theses (Open Access)

PDF

THE ROLE OF A2B ADENOSINE RECEPTOR SIGNALING IN ADENOSINE DEPENDENT LUNG DISEASE, Yang Zhou
Dissertations and Theses (Open Access)

PDF

XENOESTROGEN-SPECIFIC MECHANISMS OF DEVELOPMENTAL REPROGRAMMING CORRELATE WITH GENE EXPRESSION AND TUMOR DEVELOPMENT, Kristen L. Greathouse
Dissertations and Theses (Open Access)

PDF

PREECLAMPSIA, AUTOIMMUNITY AND THE AT1 RECEPTOR, Roxanna A. Irani
Dissertations and Theses (Open Access)

PDF

2009

THE PHYSIOLOGICAL AND BIOCHEMICAL UNDERSTANDING OF 5’-AMP INDUCED DEEP HYPOMETABOLISM, William G. O'Brien
Dissertations and Theses (Open Access)

PDF

1980

FUNCTIONS OF DEADENYLATION FACTORS IN MRNA DECAY AND MRNA PROCESSING BODY FORMATION, Dinghai Zheng
Dissertations and Theses (Open Access)

PDF