Part of the Genetics and Genomics Commons

Works in Genetics and Genomics

2023

Genetic analysis of crossover defective mouse spermatocytes reveals discrete crossover precursor intermediates, Tolkappiyan Prem Kumar
Dissertations and Theses (Open Access)

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DeepHTLV: a Deep Learning Framework for Detecting Human T-Lymphotrophic Virus 1 Integration Sites, Johnathan Jia, Johnathan Jia
Dissertations and Theses (Open Access)

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UNIQUE TRANSCRIPTIONAL PROFILES UNDERLIE OSTEOSARCOMAGENESIS DRIVEN BY DIFFERENT p53 MUTANTS, Dhruv Chachad
Dissertations and Theses (Open Access)

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The Need for Racial and Ethnic Health Disparity Curriculum in Genetic Counseling Programs, Yusra Aziz
Dissertations and Theses (Open Access)

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Regulation of de novo and Maintenance DNA Methylation by DNMT3A and DNMT3B, Yang Zeng
Dissertations and Theses (Open Access)

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TARGETING METABOLIC ALTERATIONS ASSOCIATED WITH SMOOTH MUSCLE α-ACTIN PATHOGENIC VARIANT ATTENUATES MOYAMOYA-LIKE CEREBROVASCULAR DISEASE, Anita Kaw
Dissertations and Theses (Open Access)

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RECONSTRUCTING MUTATIONAL LINEAGES IN BREAST CANCER BY MULTI-PATIENT-TARGETED SINGLE CELL DNA SEQUENCING, Jake Leighton
Dissertations and Theses (Open Access)

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P53 DIMERS ELICIT UNIQUE TUMOR SUPPRESSIVE ACTIVITIES THROUGH AN ALTERED METABOLIC PROGRAM, Jovanka Gencel-Augusto
Dissertations and Theses (Open Access)

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Functions of the tRNA splicing endonuclease and other adventures in RNA processing, Jennifer Hurtig, Ambro van Hoof
Dissertations and Theses (Open Access)

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Prenatal Screening Decision-making Facilitated Through an Online Patient Education Module, Erin Atkinson
Dissertations and Theses (Open Access)

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The Diagnostic Odyssey of Hypermobile EDS Patients: Diagnosis, Clinical Expectations, and Psychosocial Concerns, Madeline Alpar
Dissertations and Theses (Open Access)

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Genetic Regulation of Müllerian Duct Regression, Malcolm Moses
Dissertations and Theses (Open Access)

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2022

MED12 Is A Critical Regulator of Neural Crest Lineage and Nervous System Myelination, FATMA BETUL AKSOY YASAR
Dissertations and Theses (Open Access)

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Genetic analysis of RNA exosome complex cofactors, Luisa Orlando
Dissertations and Theses (Open Access)

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Redox sensing by yeast Hsp70 facilitates modulation of protein quality control and the cytoprotective response, Alec Santiago
Dissertations and Theses (Open Access)

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Roles of oxidative stress and DNA methylation in cigarette smoking-induced accelerated acute myeloid leukemia progression, Mary Figueroa
Dissertations and Theses (Open Access)

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The Role of the Hypoxia-Inducible Factor 2 in Pancreatic Cancer: Mechanisms of Tumor Immunosuppression and Intestinal Radioprotection, Carolina Garcia Garcia
Dissertations and Theses (Open Access)

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Yap and Taz are Required for Neural Crest-Derived Cardiovascular Development, Shannon Erhardt
Dissertations and Theses (Open Access)

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Genomewide CRISPR/Cas9 Screen Identifies Network of Protein Complexes that Regulate TRIM24, Lalit Patel
Dissertations and Theses (Open Access)

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Development of Graphical Models and Statistical Physics Motivated Approaches to Genomic Investigations, Yashwanth Lagisetty
Dissertations and Theses (Open Access)

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Decoding the Tumor and Immune Microenvironment in PDAC and Breast Cancer by Single Cell Sequencing., Aislyn Schalck
Dissertations and Theses (Open Access)

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HAPLOTYPE-INFORMED ALLELIC IMBALANCE DETECTION FROM RNA IN CANCER, Zuhal Ozcan
Dissertations and Theses (Open Access)

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Decoding Copy Number Substructure and Evolution from Single Cell Genomics, Darlan Conterno Minussi
Dissertations and Theses (Open Access)

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COMPUTATIONAL APPROACHES TO UNDERSTAND CHEMORESISTANCE & TUMOR EVOLUTION USING LONGITUDINAL CLINICAL DATA AND LINEAGE TRACING, Sahil Seth
Dissertations and Theses (Open Access)

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Invisible Disabilities, Academic Capital and Competitiveness of Genetic Counseling Applicants, Natalie E. Stoner, Meagan Choates, Carla McGruder, Debra Murray, Theresa Wittman, Sara Wofford, Claire N. Singletary
Dissertations and Theses (Open Access)

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Prenatal Testing Decisions and Motivations in Pregnancies Conceived via In Vitro Fertilization, Michelle Appel
Dissertations and Theses (Open Access)

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Parental Stress in Tuberous Sclerosis Complex, Jenny Do
Dissertations and Theses (Open Access)

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NOVEL REGULATORS OF CELLULAR SECRETION ALTER THE TUMOR MICROENVIRONMENT TO DRIVE METASTASIS, Rakhee Bajaj
Dissertations and Theses (Open Access)

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EXPLOITING CHEMOGENETIC AND GENETIC INTERACTIONS IN HUMAN CELLS AS AN AVENUE FOR NEW THERAPEUTIC OPPORTUNITIES, Medina Colic
Dissertations and Theses (Open Access)

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An Investigation of Epigenetic Mechanisms Driving the Biology of Head and Neck Squamous Cell Carcinoma, Scot Carson Callahan
Dissertations and Theses (Open Access)

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INVESTIGATING THE ECOLOGY AND EVOLUTION OF NORMAL BREAST TISSUES AND BREAST CANCER WITH SINGLE CELL GENOMICS, Tapsi Kumar, Tapsi Kumar
Dissertations and Theses (Open Access)

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DEVELOPMENT OF THE ARK ASSAY FOR QUANTITATING DNA- PROTEIN CROSSLINK ACCUMULATION AND FANCONI ANEMIA PATHWAY INVOLVEMENT IN THE REPAIR PROCESS, Naeh Klages-Mundt
Dissertations and Theses (Open Access)

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EXPERIENCES OF RACIAL AND ETHNIC MINORITY PATIENTS WITH GENETIC COUNSELING, Emile Moura Coelho da Silva
Dissertations and Theses (Open Access)

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2021

DECIPHERING THE ROLE OF HSP110 CHAPERONES IN DISEASES OF PROTEIN MISFOLDING, Unekwu M. Yakubu
Dissertations and Theses (Open Access)

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Mutant KRAS Alters Extracellular Vesicle MicroRNA Sorting in Pancreatic Cystic Neoplasms, Rachel L. Dittmar
Dissertations and Theses (Open Access)

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Targeting Plasma Membrane Phosphatidylserine Content to Inhibit Oncogenic KRAS Function, Walaa E. Kattan
Dissertations and Theses (Open Access)

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NPSD4: A NEW PLAYER IN SUMO-DEPENDENT DNA REPAIR, Erin Atkinson
Dissertations and Theses (Open Access)

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REGULATION OF LUNG MESENCHYMAL CELLS BY EPITHELIAL WNT LIGANDS, Odemaris Narvaez del Pilar
Dissertations and Theses (Open Access)

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Understanding the Pathogenesis of Renal Medullary Carcinoma, Melinda Soeung
Dissertations and Theses (Open Access)

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EPITHELIAL MEMORY OF RESOLVED INFLAMMATION LIMITS TISSUE DAMAGE WHILE PROMOTING PANCREATIC TUMORIGENESIS, I-Lin Ho
Dissertations and Theses (Open Access)

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Unveiling global roles of G-quadruplexes and G4-22 in human genetics, Ruth Barros De Paula
Dissertations and Theses (Open Access)

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UNDERSTANDING THE ROLE OF ARGLU1 IN INTERFERON SIGNALING ACTIVATION IN BREAST CANCER, Phuoc Nguyen
Dissertations and Theses (Open Access)

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Impact of Intratumor Heterogeneity and the Tumor Microenvironment in Shaping Tumor Evolution and Response to Therapy, Akash Mitra
Dissertations and Theses (Open Access)

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Rare variant association studies in Crohn’s Disease and Colorectal Cancer: methods and applications, Jiun-Sheng Chen
Dissertations and Theses (Open Access)

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Genetic Pathway Analysis of Abnormal Facial Development in Nonsyndromic Cleft Lip and Palate, lorena maili
Dissertations and Theses (Open Access)

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FUNCTIONS OF DCP2 AND SKI7 IN MRNA DEGRADATION, Minseon Kim, Ambro van Hoof
Dissertations and Theses (Open Access)

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Assessing Genetic Counselors' Clinical Approach and Practices Regarding Pathogenic/Likely Pathogenic Variant Downgrades, Grant Bonesteele
Dissertations and Theses (Open Access)

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Spectrum and Incidence of Primary and Therapy-Related Hematologic Malignancies in Individuals with BRCA1 and BRCA2 Pathogenic Variants, Rosemary Rogers, Rosemary Rogers
Dissertations and Theses (Open Access)

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DISCOVERY OF NOVEL UBIQUITIN- AND METHYLATION-DEPENDENT INTERACTIONS USING PROTEIN DOMAIN MICROARRAYS, Jianji Chen
Dissertations and Theses (Open Access)

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Computational Approaches to Delineate Transcriptional and Functional Heterogeneity in Pancreatic Cancer, Sanjana Srinivasan
Dissertations and Theses (Open Access)

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BIASES AND BLIND-SPOTS IN GENOME-WIDE CRISPR-CAS9 KNOCKOUT SCREENS, Merve Dede
Dissertations and Theses (Open Access)

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Mixture Model Approaches to Integrative Analysis of Multi-Omics Data and Spatially Correlated Genomic Data, Ziqiao Wang
Dissertations and Theses (Open Access)

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Evaluating Insurance Approval Rates of Exome Sequencing and its Effect on Minority Patients' Access to Genetic Care, Katlyn Frane
Dissertations and Theses (Open Access)

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Investigating Barriers Experienced by Underrepresented Minorities in Becoming a Competitive Genetic Counseling Applicant, Katie Huang
Dissertations and Theses (Open Access)

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2020

DECODING THE EVOLUTIONARY RESPONSE TO PROSTATE CANCER THERAPY USING PLASMA GENOME SEQUENCING, Naveen Ramesh
Dissertations and Theses (Open Access)

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INVESTIGATION OF PROLIFERATION SUPPRESSORS IN GENETIC FITNESS SCREENS, Walter Frank Lenoir IV
Dissertations and Theses (Open Access)

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A CONTEXT-FORWARD IN VIVO FUNCTIONAL GENOMICS PLATFORM FOR TARGET DISCOVERY AND ESTABLISHING VULNERABILITY CONTEXT IN PANCREATIC CANCER, Johnathon Rose, Johnathon Lynn Rose
Dissertations and Theses (Open Access)

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GENETIC AND CLINICAL DETERMINANTS OF RACIAL/ETHNIC DIFFERENCES IN MULTIPLE MYELOMA SUSCEPTIBILITY AND OUTCOMES FOCUSING ON HISPANICS, Alem Belachew
Dissertations and Theses (Open Access)

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p53 drives a transcriptional program that elicits a non-cell-autonomous response and alters cell state in vivo, Sydney Moyer
Dissertations and Theses (Open Access)

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The Genome-Wide Roles of the Lung Lineage Transcription Factor NKX2-1 in the Regulation of Opposing Cell Fates In Vivo, Danielle Renae Little
Dissertations and Theses (Open Access)

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IDENTIFICATION OF TRIM24 DOMAIN ESSENTIALITY IN PRIMARY TRIM24COE CARCINOSARCOMA CELL LINES, Cem Dede
Dissertations and Theses (Open Access)

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Statistical Methods for Resolving Intratumor Heterogeneity with Single-Cell DNA Sequencing, Alexander Davis
Dissertations and Theses (Open Access)

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Artificial intron technology to generate conditional knock-out mice, Amber N. Thomas-Gordon
Dissertations and Theses (Open Access)

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LONGITUDINAL CLONAL LINEAGE DYNAMICS AND FUNCTIONAL CHARACTERIZATION OF PANCREATIC CANCER CHEMO-RESISTANCE AND METASTASIZATION, Chieh-Yuan Li
Dissertations and Theses (Open Access)

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LOSS OF CASPASE-8 FUNCTION IN COMBINATION WITH SMAC MIMETIC TREATMENT SENSITIZES HEAD AND NECK SQUAMOUS CARCINOMA TO RADIATION THROUGH INDUCTION OF NECROPTOSIS., Burak Uzunparmak
Dissertations and Theses (Open Access)

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Heterogeneous Nuclear Ribonucleoprotein K (hnRNP K) Overexpression and its Interaction with RUNX1 RNA in Acute Myeloid Leukemia, Marisa Aitken
Dissertations and Theses (Open Access)

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Factors that Impact Uptake of Carrier Screening by Male Reproductive Partners of Female Prenatal Patients, Wendi Betting
Dissertations and Theses (Open Access)

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MULTIPLEXED CRISPR LIBRARIES FOR CANCER FUNCTIONAL GENOMICS, Jintan Liu
Dissertations and Theses (Open Access)

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10th Annual Postdoctoral Science Symposium, University of Texas MD Anderson Cancer Center PostDoctoral Association
MD Anderson Cancer Center Postdoctoral Association Annual Postdoctoral Science Symposium Abstracts

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2019

9th Annual Postdoctoral Science Symposium, University of Texas MD Anderson Cancer Center PostDoctoral Association
MD Anderson Cancer Center Postdoctoral Association Annual Postdoctoral Science Symposium Abstracts

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MOLECULAR CONSEQUENCES OF HIGH TAZ EXPRESSION IN GLIOMAS, Visweswaran Ravikumar
Dissertations and Theses (Open Access)

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Investigating the role of CD109 in Pancreatic Ductal Adenocarcinoma, MennatAllah Shaheen
Dissertations and Theses (Open Access)

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P53R245W MUTATION ELICITS METASTATIC PHENOTYPE IN PTEN DEFICIENT PROSTATE CANCER, Ky Pham
Dissertations and Theses (Open Access)

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MODELING CANCER USING LI-FRAUMENI SYNDROME PATIENT-DERIVED INDUCED PLURIPOTENT STEM CELLS, Ruoji Zhou
Dissertations and Theses (Open Access)

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Identifying Interest in and Barriers to Psychiatric Genetic Counseling, Samantha Montgomery
Dissertations and Theses (Open Access)

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Identifying Pathogenic Variants in Hereditary Cancer Syndrome Genes via Tumor Molecular Profiling, Carol Nowlen
Dissertations and Theses (Open Access)

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Hypoglycemia in Mitochondrial Disorders, Allison Moats
Dissertations and Theses (Open Access)

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Higher order chromosome organization and recombination dynamics of meiotic prophase I in mouse spermatocytes, Rhea Kang
Dissertations and Theses (Open Access)

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PLATISCITY OF C. ELEGANS GERMLINE STEM CELLS UNDER NUTRITIONAL AND METABOLIC STRESS, Kenneth Trimmer
Dissertations and Theses (Open Access)

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Sequence-Specific Gene Correction of Cystic Fibrosis Airway Basal Cells, Varada Anirudhan
Dissertations and Theses (Open Access)

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COMPUTATIONAL GENOMIC MODELS FOR SPATIO-TEMPORAL INVESTIGATION OF EARLY LUNG CANCER PATHOLOGY, Smruthy Sivakumar
Dissertations and Theses (Open Access)

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GENETIC COUNSELOR UTILIZATION AND INTERPRETATION OF SOMATIC TUMOR TESTING IN EVALUATION FOR LYNCH SYNDROME, Danielle Williams
Dissertations and Theses (Open Access)

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Thiol-based Misfolding: Linking Redox Balance to Cytosolic Proteostasis, Ford Amy
Dissertations and Theses (Open Access)

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2018

The Role of Tumor Suppressor DEAR1 in the Acquisition of Mammary Stem/Progenitor Cell Properties, Uyen Le
Dissertations and Theses (Open Access)

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GENETIC EVOLUTION AND PROGNOSTIC DETERMINANTS OF PANCREATIC CANCER ON LONGITUDINAL LIQUID BIOPSIES, Vincent Bernard
Dissertations and Theses (Open Access)

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Improving dbNSFP, Mingyao Lu
Dissertations and Theses (Open Access)

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8th Annual Postdoctoral Science Symposium, University of Texas MD Anderson Cancer Center PostDoctoral Association
MD Anderson Cancer Center Postdoctoral Association Annual Postdoctoral Science Symposium Abstracts

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Mechanism of Incorporation and Repair of Uracil at Highly Transcribed Genes In Saccharomyces Cerevisiae, Norah Auma Owiti
Dissertations and Theses (Open Access)

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MICRORNA FUNCTIONS IN UV-INDUCED CUTANEOUS SQUAMOUS CELL CARCINOMA, Tran Nguyen
Dissertations and Theses (Open Access)

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GENOMIC AND TRANSCRIPTOMIC LANDSCAPE OF COLORECTAL PREMALIGNANCY, Kyle Chang
Dissertations and Theses (Open Access)

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Omics Approaches to Uncover Germline and Somatic Variation Underlying Inherited Sarcomagenesis, Justin Wong
Dissertations and Theses (Open Access)

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INVESTIGATING THE ROLES OF TAP63 AND TAP73 IN CUTANEOUS SQUAMOUS CELL CARCINOMA AND LUNG ADENOCARCINOMA, Andrew J. Davis
Dissertations and Theses (Open Access)

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An expanded toolkit for gene tagging based on MiMIC and scarless CRISPR tagging in, David Li-Kroeger, Oguz Kanca, Pei-Tseng Lee, Sierra Cowan, Michael T Lee, Manish Jaiswal, Jose Luis Salazar, Yuchun He, Zhongyuan Zuo, Hugo J Bellen
BCM Faculty Publications

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Computational insights into the generation of chromosomal copy number changes, Yihua Liu
Dissertations and Theses (Open Access)

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GENETIC TESTING PRACTICES OF GENETIC COUNSELORS, GENETICISTS, AND PEDIATRIC NEUROLOGISTS WITH REGARD TO CHILDHOOD-ONSET NEUROGENETIC CONDITIONS, Sara Wofford
Dissertations and Theses (Open Access)

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EXAMINING THE RELATIONSHIP BETWEEN GENETIC COUNSELORS’ IMPLICIT ATTITUDES TOWARD DISABILITY AND THEIR PRACTICE METHODS, Helen W. Gould
Dissertations and Theses (Open Access)

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The Regulation of DNA Methylation in Mammalian Development and Cancer, Nicolas Veland
Dissertations and Theses (Open Access)

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VASCULAR INJURY IN Col3a1+/- MICE MODEL OF VASCULAR EHLER-DANLOS SYNDROME, Ping ZHOU MS
Dissertations and Theses (Open Access)

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IDENTIFICATION AND UTILITY OF DNA IN EXOSOMES, Paul Kurywchak
Dissertations and Theses (Open Access)

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TRIM24 as an Oncogene in the Mammary Gland, Aundrietta Duncan
Dissertations and Theses (Open Access)

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INVESTIGATING INVASION IN DUCTAL CARCINOMA IN SITU WITH TOPOGRAPHICAL SINGLE CELL GENOME SEQUENCING, Anna Casasent, Anna Casasent
Dissertations and Theses (Open Access)

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PHOSPHORYLATION IMPAIRS DICER1 FUNCTION TO ACCELERATE AGING AND TUMORIGENESIS IN VIVO, Neeraj Aryal
Dissertations and Theses (Open Access)

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The Role of Merlin and Apicobasal Polarity in Endometrial Development and Homeostasis, Erin Lopez
Dissertations and Theses (Open Access)

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Trim24 in Normal & Malignant Hematopoiesis, Justin Shaw
Dissertations and Theses (Open Access)

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EVOLUTION VIA GENE DUPLICATION AND ALTERNATIVE SPLICING IN THE EUKARYOTIC SKI7 AND HBS1 GENES, Alexandra Marshall
Dissertations and Theses (Open Access)

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Patient Attitudes Toward Genetic Testing for Inherited Predispositions to Hematologic Malignancies, Taylor Beecroft
Dissertations and Theses (Open Access)

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Attitudes Toward Updated Genetic Testing Among Patients with Unexplained Mismatch Repair Deficiency, Jessica Omark
Dissertations and Theses (Open Access)

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Functional Similarity of PRD-Containing Virulence Regulators in Bacillus anthracis, Malik Raynor
Dissertations and Theses (Open Access)

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Outcomes of Genetic Testing in a Genitourinary Genetics Clinic, Annelise Pace
Dissertations and Theses (Open Access)

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Psychiatric Impact of Tuberous Sclerosis Complex and Utilization of Mental Health Treatment, Kate Mowrey
Dissertations and Theses (Open Access)

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INVESTIGATING THE IMPACT OF INTRAGENIC DNA METHYLATION ON GENE EXPRESSION, AND THE CLINICAL IMPLICATIONS ON TUMOR CELLS AND ASSOCIATED STROMA, Michael McGuire
Dissertations and Theses (Open Access)

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2017

Quality of Life: Socio-Demographic and Genetic Determinants as well as Links with Cancer Outcomes, Jeanne Pierzynski
Dissertations and Theses (Open Access)

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EVALUATING THE THERAPEUTIC EFFICACY OF RESTORING WILD-TYPE P53 ACTIVITY IN P53-MUTANT TUMORS, Connie A. Larsson
Dissertations and Theses (Open Access)

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INTEGRATIVE CANCER IMMUNOGENOMIC ANALYSIS OF SERIAL MELANOMA BIOPSIES REVEALS CORRELATES OF RESPONSE AND RESISTANCE TO SEQUENTIAL CTLA-4 AND PD-1 BLOCKADE TREATMENT, Whijae Roh
Dissertations and Theses (Open Access)

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Functional consequences of RNA exosome complex alteration by conformational changes and cofactor binding, Jaeil Han
Dissertations and Theses (Open Access)

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WISP1 IS AN OVEREXPRESSED DRIVER OF GLIOBLASTOMA, Pushan R. Dasgupta
Dissertations and Theses (Open Access)

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Attitudes of Clinicians Towards Cardiac Surgery and Trisomy 18, Meagan Kaulfus
Dissertations and Theses (Open Access)

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Undergraduate Student Perceptions and Awareness of Genetic Counseling, Amanda Gerard
Dissertations and Theses (Open Access)

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UNDERSTANDING THE MECHANISM OF GENOMIC INSTABILITY DURING REPLICATIVE AGING IN BUDDING YEAST, Sangita Pal
Dissertations and Theses (Open Access)

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ANALYSIS OF THE BIOCHEMICAL AND CELLULAR ACTIVITIES OF SUBSTRATE BINDING BY THE MOLECULAR CHAPERONE HSP110/SSE1, Veronica M. Garcia
Dissertations and Theses (Open Access)

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NON-CODING RNAS IDENTIFY THE INTRINSIC MOLECULAR SUBTYPES OF MUSCLE-INVASIVE BLADDER CANCER, Andrea E. Ochoa
Dissertations and Theses (Open Access)

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Statistical Methods for Two Problems in Cancer Research: Analysis of RNA-seq Data from Archival Samples and Characterization of Onset of Multiple Primary Cancers, Jialu Li
Dissertations and Theses (Open Access)

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Barriers to Expansion of Supervision Networks at Genetic Counseling Training Programs, Jordan E. Berg
Dissertations and Theses (Open Access)

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PROTEOMIC IDENTIFICATION OF HISTONE POST-TRANSLATIONAL MODIFICATIONS INDUCED BY DNA DOUBLE-STRAND BREAKS AND NOVEL PROTEINS INVOLVED IN THE DNA DAMAGE RESPONSE, Pingping Wang
Dissertations and Theses (Open Access)

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Attitudes Toward and Uptake of Prenatal Genetic Screening and Testing in Twin Pregnancies, Kathryn M. Reese
Dissertations and Theses (Open Access)

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The Utilization of Prenatal Microarray: A Survey of Current Genetic Counseling Practices and Barriers, Leslie N. Durham, Leslie Durham
Dissertations and Theses (Open Access)

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A rare case of erythema elevatum diutinum presenting as diffuse neuropathy., G H. Nguyen, E L. Guo, D Norris
BCM Faculty Publications

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2016

USING MOUSE MODELS TO DEFINE HOW THE P53 R72P POLYMORPHISM IMPACTS THE ADVERSE EFFECTS OF DOXORUBICIN AND IONIZING RADIATION, Emily Dominguez
Dissertations and Theses (Open Access)

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CONCOMITANT TARGETING OF THE MTOR/MAPK PATHWAYS: NOVEL THERAPEUTIC STRATEGY IN SUBSETS OF NON-SMALL CELL LUNG CANCER, Dennis Ruder
Dissertations and Theses (Open Access)

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Consensus Paper: Cerebellar Development., K Leto, M Arancillo, EBE Becker, A Chiang, et al.
BCM Faculty Publications

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Characterization of Vesicular Monoamine Transporter 2 and its role in Parkinson's Disease Pathogenesis using Drosophila, Antonio Joel Tito Jr., Sheng Zhang
Dissertations and Theses (Open Access)

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Development Of An In Silico Kir Genotyping Algorithm And Its Application To Population And Cancer Immunogenetic Analyses, Howard Rosoff
Dissertations and Theses (Open Access)

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GENOMIC DRIVERS OF CUTANEOUS SQUAMOUS CELL CARCINOMA DEVELOPMENT, Vida Chitsazzadeh
Dissertations and Theses (Open Access)

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NIPT Results Indicative of Maternal Neoplasms: Genetic Counselors' Preferences and Attitudes, Meagan E. Giles
Dissertations and Theses (Open Access)

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THE THIOREDOXIN TRX-1 REGULATES THE MAJOR OXIDATIVE STRESS RESPONSE TRANSCRIPTION FACTOR, SKN-1, IN CAENORHABDITIS ELEGANS, Katie C. McCallum
Dissertations and Theses (Open Access)

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THE ROLES OF MALT1 IN NF-κB ACTIVATION AND SOLID TUMOR PROGRESSION, Deng Pan
Dissertations and Theses (Open Access)

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Ethnic Identity and Teratogenic Risk Perceptions, Katie M. Chan
Dissertations and Theses (Open Access)

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Investigating Metastatic Lineage in Colorectal Cancer by Single Cell DNA Sequencing, Marco Leung
Dissertations and Theses (Open Access)

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Accurate mutation annotation and functional prediction enhance the applicability of -omics data in precision medicine, Tenghui Chen
Dissertations and Theses (Open Access)

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Comparison of interactive voice response (IVR) with paper administration of instruments to assess functional status, sexual function, and quality of life in elderly men., RC Rosen, AJ Stephens-Shields, GR Cunningham, D Cifelli, D Cella, JT Farrar, E Barrett-Connor, CE Lewis, M Pahor, X Hou, PJ Snyder
BCM Faculty Publications

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Explicit Time Deficit in Schizophrenia: Systematic Review and Meta-Analysis Indicate It Is Primary and Not Domain Specific., V Ciullo, G Spalletta, C Caltagirone, RE Jorge, F Piras
BCM Faculty Publications

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Is Whole-Exome Sequencing an Ethically Disruptive Technology? Perspectives of Pediatric Oncologists and Parents of Pediatric Patients With Solid Tumors., Laurence B McCullough, Melody J Slashinski, Amy L McGuire, Richard L Street, Christine M Eng, Richard A Gibbs, D William Parsons, Sharon E Plon
BCM Faculty Publications

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Identification of an Association of TNFAIP3 Polymorphisms With Matrix Metalloproteinase Expression in Fibroblasts in an Integrative Study of Systemic Sclerosis-Associated Genetic and Environmental Factors.*, Peng Wei, Yang Yang, Xinjian Guo, Nainan Hei, Syeling Lai, Shervin Assassi, Mengyuan Liu, Filemon Tan, Xiaodong Zhou
BCM Faculty Publications

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CT-based Structural Rigidity Analysis Is More Accurate Than Mirels Scoring for Fracture Prediction in Metastatic Femoral Lesions., TA Damron, A Nazarian, V Entezari, C Brown, W Grant, N Calderon, et al.
BCM Faculty Publications

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Glial Contributions to Neural Function and Disease., MN Rasband
BCM Faculty Publications

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Eosinophilic Esophagitis in Children and Its Relationship with Parental Allergies: Texas Children's Hospital Experience., G Hiremath, D Byramji, A Pacheco, G Constantine, C Davis, R Shulman, A Olive
BCM Faculty Publications

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Efficacy of Psychosocial Interventions in Inducing and Maintaining Alcohol Abstinence in Patients With Chronic Liver Disease: A Systematic Review., A Khan, A Tansel, DL White, WT Kayani, WT Bano, J Lindsay, HB El-Serag, F Kanwal
BCM Faculty Publications

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Early rescue of interneuron disease trajectory in developmental epilepsies., MS Siehr, JL Noebels
BCM Faculty Publications

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Effect of Two-Year Caloric Restriction on Bone Metabolism and Bone Mineral Density in Non-Obese Younger Adults: A Randomized Clinical Trial., DT Villareal, L Fontana, SK Das, et al.
BCM Faculty Publications

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Identification of a Novel Gene on 10q22.1 Causing Autosomal Dominant Retinitis Pigmentosa (adRP)., Stephen P Daiger, Lori S Sullivan, Sara J Bowne, Daniel C Koboldt, Susan H Blanton, Dianna K Wheaton, Cheryl E Avery, Elizabeth D Cadena, Robert K Koenekoop, Robert S Fulton, Richard K Wilson, George M Weinstock, Richard A Lewis, David G Birch
BCM Faculty Publications

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2015

PREVENTING THYMUS INVOLUTION IN K5.CYCLIN D1 TRANSGENIC MICE SUSTAINS THE NAÏVE T CELL COMPARTMENT WITH AGE, Michelle L. Bolner
Dissertations and Theses (Open Access)

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IN VIVO FUNCTIONAL SIGNIFICANCE OF CCAT2 LONG NON-CODING RNA IN MYELODYSPLASTIC SYNDROME, MAITRI Y. SHAH
Dissertations and Theses (Open Access)

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FUNCTIONAL ANALYSIS OF SYNTHETIC GENE CIRCUITS CONTROLLING A PROTEIN PUMP IN YEAST, Junchen Diao
Dissertations and Theses (Open Access)

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Detection of Genes Influencing Chronic and Mendelian Disease via Loss-Of-Function Variation, Alexander H. Li
Dissertations and Theses (Open Access)

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Germline Mutation Detection in Next Generation Sequencing Data and TP53 Mutation Carrier Probability Estimation for Li-Fraumeni Syndrome, Gang Peng
Dissertations and Theses (Open Access)

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IDENTIFICATION OF FAMILIAL WILMS TUMOR PREDISPOSITION GENES USING WHOLE GENOME SEQUENCING, Timothy B. Palculict
Dissertations and Theses (Open Access)

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IN VIVO SIGNIFICANCE OF THE MDM4 AND P73 INTERACTION DURING DEVELOPMENT AND TUMORIGENESIS, Mehrnoosh Tashakori
Dissertations and Theses (Open Access)

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Elucidating the role of Rumi and O-glucosylation in the Drosophila eye, Amanda Haltom
Dissertations and Theses (Open Access)

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IGFBP2 POTENTIATES EGFR-STAT3 SIGNALING IN GLIOMA, Yingxuan Chua
Dissertations and Theses (Open Access)

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IMPACT OF DIFFERENTIATION STATUS OF KIDNEY PROGENITORS IN WILMS TUMOR DEVELOPMENT, Le Huang
Dissertations and Theses (Open Access)

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INVESTIGATION OF GENETIC ALTERATIONS IN EMT SUPPRESSOR, DEAR1, THROUGH PAN-CANCER ANALYSIS AND ULTRA-DEEP TARGETED SEQUENCING IN DUCTAL CARCINOMA IN SITU, Jacquelyn Reuther
Dissertations and Theses (Open Access)

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GENETICS OF OBESITY IN STARR COUNTY, TEXAS MEXICAN AMERICANS, Heather M. Highland
Dissertations and Theses (Open Access)

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DNA POLYMERASE θ (POLQ) AND THE CELLULAR DEFENSE AGAINST DNA DAMAGE, Matthew J. Yousefzadeh
Dissertations and Theses (Open Access)

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Investigating the roles of p63 and p73 isoforms to therapeutically treat p53-altered cancers, Avinashnarayan Venkatanarayan
Dissertations and Theses (Open Access)

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Spiritual Exploration in the Prenatal Genetic Counseling Session, Katelynn G. Sagaser
Dissertations and Theses (Open Access)

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Evaluating the NCCN Clinical Criteria for Hereditary Breast and Ovarian Cancer Syndrome Genetic Testing, Caiqian Wu
Dissertations and Theses (Open Access)

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2014

IDENTIFICATION OF CELL SIGNALING PATHWAY REGULATED BY MICRORNAS IN CANCER CELLS USING A SYSTEMS BIOLOGICAL APPROACH, sangbae Kim
Dissertations and Theses (Open Access)

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Large-scale Identification of Chemically Induced Mutations in Drosophila melanogaster., Nele A Haelterman, Lichun Jiang, Yumei Li, Vafa Bayat, Hector Sandoval, Berrak Ugur, Kai Li Tan, Ke Zhang, Danqing Bei, Bo Xiong, Wu-Lin Charng, Theodore Busby, Adeel Jawaid, Gabriela David, Manish Jaiswal, Koen J T Venken, Shinya Yamamoto, Rui Chen, Hugo J Bellen
BCM Faculty Publications

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DISCOVERY AND ELUCIDATION OF THE FGFR3-TACC3 RECURRENT FUSION IN GLIOBLASTOMA, Brittany C. Parker Kerrigan
Dissertations and Theses (Open Access)

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Utilizing Haplotypes for Sensitive SNP Array-based Discovery of Somatic Chromosomal Mutations, Selina M. Vattathil
Dissertations and Theses (Open Access)

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GENETIC PREDICTORS OF METABOLIC SIDE EFFECTS OF DIURETIC THERAPY, Jorge L. Del Aguila
Dissertations and Theses (Open Access)

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Genomic Characterization of Polyps in Familial Adenomatous Polyposis Patients and Identification of Candidate Chemopreventive Drugs, Francis A. San Lucas
Dissertations and Theses (Open Access)

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DEVELOPMENT OF CHIMERIC TYPE IV SECRETION SYSTEMS FOR TRANSFER OF HETEROLOGOUS SUBSTRATES ACROSS THE GRAM-NEGATIVE CELL ENVELOPE, Trista M. Berry
Dissertations and Theses (Open Access)

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Potential Roles of Peroxidases in Caenorhabditis Elegans Innate Immunity, George R. Tiller, george r. tiller
Dissertations and Theses (Open Access)

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DEVELOPMENT OF A MOLECULAR GRAM-STAIN ASSAY FOR THE DIAGNOSIS OF BLOOD STREAM INFECTIONS ASSOCIATED WITH SEPSIS, Douglas Bryan Litwin
Dissertations and Theses (Open Access)

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Chemical mutagens, transposons, and transgenes to interrogate gene function in Drosophila melanogaster., Koen J T Venken, Hugo J Bellen
BCM Faculty Publications

CHARACTERIZATION OF FTSA-FTSN INTERACTION DURING ESCHERICHIA COLI CELL DIVISION, kimberly.busiek@gmail.com K. Busiek
Dissertations and Theses (Open Access)

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THE ASSOCIATION BETWEEN THE IL-1 PATHWAY, Isaac C. Wun
Dissertations and Theses (Open Access)

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p53 MAINTAINS HEPATIC CELL IDENTITY DURING LIVER REGENERATION, Zeynep Hande Coban Akdemir
Dissertations and Theses (Open Access)

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MODULATED FUNCTIONS OF THE FANCONI ANEMIA CORE COMPLEX, Yaling Huang
Dissertations and Theses (Open Access)

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NATURAL AND EXOGENOUS GENOME EDITING IN WISKOTT-ALDRICH SYNDROME PATIENT CELLS, Tamara J. Laskowski
Dissertations and Theses (Open Access)

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2013

c-REL is a Transcriptional Target of Mesoderm Inducer in Xenopus Like 1 (MIXL1), Aaron C. Raymond
Dissertations and Theses (Open Access)

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THERAPEUTIC EFFICACY OF P53 RESTORATION IN MDM2-OVEREXPRESSING TUMORS, Qin Li
Dissertations and Theses (Open Access)

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INTRODUCING A NOVEL METHOD FOR GENETIC ANALYSIS OF AUTISM SPECTRUM DISORDER, sepideh nouri
Dissertations and Theses (Open Access)

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PRKCa: Identification of a Novel Downstream Target of WT1, Devin Jones
Dissertations and Theses (Open Access)

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RNA-SEQUENCING APPLICATIONS: GENE EXPRESSION QUANTIFICATION AND METHYLATOR PHENOTYPE IDENTIFICATION, Guoshuai Cai
Dissertations and Theses (Open Access)

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Delayed Thrombus Resolution and Fibroproliferative Vascular Wound Healing From Deficiency of Type III Collagen: a Paradoxical Mechanism for Tissue Fragility, Amy J. Reid
Dissertations and Theses (Open Access)

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THE NATURAL AND ORTHOGONAL INTERACTION (NOIA) MODELS FOR QUANTITATIVE TRAITS (QTs) AND COMPLEX DISEASES, Feifei Xiao
Dissertations and Theses (Open Access)

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MOLECULAR AND GENOMIC BASED INSIGHTS INTO THE EVOLUTION OF ENTEROCOCCUS FAECIUM FROM COMMENSAL TO HOSPITAL-ADAPTED PATHOGEN, Jessica R. Galloway-Pena
Dissertations and Theses (Open Access)

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Knowledge and Expectations of Support People in Prenatal Genetic Counseling Sessions, Michelle A. McDougle
Dissertations and Theses (Open Access)

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Mismatch Repair Deficient Tumors Lacking Known Sporadic Causes: Are They All Due to Lynch Syndrome?, Katherine M. Dempsey
Dissertations and Theses (Open Access)

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2012

FANCM AND FAAP24 MAINTAIN GENOMIC STABILITY THROUGH COOPERATIVE AND UNIQUE FUNCTIONS, Yucai Wang
Dissertations and Theses (Open Access)

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TET1: A UNIQUE DNA DEMETHYLASE FOR MAINTENANCE OF DNA METHYLATION PATTERN, CHUNLEI JIN
Dissertations and Theses (Open Access)

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REGULATION OF ALTERNATIVE CARBON METABOLISM IN CANDIDA ALBICANS, Arely Y. Gonzalez
Dissertations and Theses (Open Access)

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GENETIC INTERACTIONS OF FACTORS THAT REGULATE ALTERNATIVE RNA SPLICING IN THE MALE GERM LINE OF DROSOPHILA, Shanzhi Wang
Dissertations and Theses (Open Access)

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IDENTIFYING GENETIC VARIANTS AND CHARACTERIZING THEIR ROLE IN CLUBFOOT, Katelyn S. Weymouth
Dissertations and Theses (Open Access)

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The Role of the Arched Helicases in Exosome-Mediated Function, A. Alejandra Klauer
Dissertations and Theses (Open Access)

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GENETIC ANALYSIS OF THE HIPPO PATHWAY IN MOUSE LIVER, Li Lu
Dissertations and Theses (Open Access)

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Potential REST Targets in Neural Stem Cells and Glioblastoma-Derived Stem Cells, Frederick Scott Robinson
Dissertations and Theses (Open Access)

Systems Biology Approaches to Probe Gene Regulation in Bacteria, Diogo F. Troggian Veiga
Dissertations and Theses (Open Access)

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FZD6, MATN2 AND SLC25A32, POSSIBLE CANDIDATE GENES IN NONSYNDROMIC CLEFT LIP AND PALATE, Nevena Cvjetkovic
Dissertations and Theses (Open Access)

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Predictors of Contralateral Breast Cancer in BRCA Negative Women, Ann E. Simmons
Dissertations and Theses (Open Access)

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Effects of thymus size and involution on the contribution of recent thymic emigrants to the peripheral T cell pool, Michelle L. Bolner
Dissertations and Theses (Open Access)

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GENETIC PREDICTORS OF HYPERGLYCEMIA DUE TO HYDROCHLOROTHIAZIDE THERAPY, Jorge L. Del Aguila
Dissertations and Theses (Open Access)

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Knowledge, Attitudes, and Utilization of BRCA Testing Among Obstetricians and Gynecologists, Salma Nassef
Dissertations and Theses (Open Access)

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2011

ROLE OF THE GCN5 HISTONE ACETYLTRANSFERASE IN SPINOCEREBELLAR ATAXIA TYPE 7 AND IN IMMATURE NEURONS, Yi Chun Chen
Dissertations and Theses (Open Access)

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IDENTIFICATION OF FACTORS INVOLVED IN DNA METHYLATION OF CPG-ISLAND-PROMOTERS, Yan Zhang
Dissertations and Theses (Open Access)

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Contribution of Ectodomain Mutations in Epidermal Growth Factor Receptor to Signaling in Glioblastoma Multiforme, Marta L. Rojas
Dissertations and Theses (Open Access)

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Gene by BMI Interactions Influencing C-Reactive Protein Levels in European-Americans, Sarah Tudor
Dissertations and Theses (Open Access)

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LDOC1, A NOVEL BIOMARKER OF PROGNOSIS IN CHRONIC LYMPHOCYTIC LEUKEMIA, Hatice Duzkale
Dissertations and Theses (Open Access)

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DOWNREGULATION OF PAX2 SUPPRESSES OVARIAN CANCER CELL GROWTH, huijuan song
Dissertations and Theses (Open Access)

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Prevalence of Premature Ovarian Failure in Women with Tuberous Sclerosis, Emily Gabitzsch
Dissertations and Theses (Open Access)

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Regulation of Set1-mediated methylation of Dam1, John A. Latham
Dissertations and Theses (Open Access)

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Gene Discovery in Nonsyndromic Cleft Lip with or without Cleft Palate, Brett T. Chiquet
Dissertations and Theses (Open Access)

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CELL POLARITY REGULATES ORGAN GROWTH THROUGH THE HIPPO PATHWAY, Chiao-Lin Chen
Dissertations and Theses (Open Access)

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COCAINE DEPENDENCE: THE ROLE OF SEROTONIN GENES IN, Lorena Maili
Dissertations and Theses (Open Access)

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THE ROLE AND MECHANISM OF THE HOMEOBOX GENE DLX4 IN TRANSFORMING GROWTH FACTOR-B RESISTANCE IN CANCER, Bon Q. Trinh
Dissertations and Theses (Open Access)

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Expression and Regulation of Human Cytochrome P450 4F Isoforms in Tissue Samples and Under TNF-Alpha Challenges, Jordan C. Bell
Dissertations and Theses (Open Access)

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2010

AGROBACTERIUM VIRB10 CONTRIBUTIONS TO TYPE IV SUBSTRATE SECRETION, T-PILUS BIOGENESIS, AND OUTER MEMBRANE PORE FORMATION, Isaac Garza
Dissertations and Theses (Open Access)

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Characterization of the Agrobacterium tumefaciens VirB2 pilin of the VirB/D4 Type IV Secretion System, Jennifer Kerr
Dissertations and Theses (Open Access)

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ELUCIDATING FUNCTIONAL ROLES FOR MYOGENIN IN ADULT SKELETAL MUSCLE METABOLISM, EXERCISE CAPACITY, AND REGENERATION, Jesse Flynn
Dissertations and Theses (Open Access)

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RMI1 is Essential for Early Embryonic Development and Attenuation of Tumor Development, Haoyi Chen
Dissertations and Theses (Open Access)

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CHARACTERIZING AND TREATING THE NEUROPATHOLOGY OF TUBEROUS SCLEROSIS COMPLEX IN THE MOUSE, Sharon W. Way
Dissertations and Theses (Open Access)

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GENETIC ANALYSIS OF THE FUNCTION OF THE DROSOPHILA DOUBLESEX-RELATED FACTOR dmrt93B, Diana O'Day
Dissertations and Theses (Open Access)

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E2F1 AND TUMOR SUPPRESSION: THE ROLE OF p21, miRNAS, AND THE DNA DAMAGE RESPONSE, Regina L. Weaks
Dissertations and Theses (Open Access)

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MODELING SPORADIC TUMOR FORMATION DRIVEN BY TELOMERE DYSFUNCTION IN THE GASTROINTESTINAL TRACT, Suzanne S. Chan
Dissertations and Theses (Open Access)

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THE DOMAINS OF THE CATALYTIC SUBUNIT OF THE EUKARYOTIC RNA DEGRADING EXOSOME, RRP44P, HAVE DISTINCT FUNCTIONS, Daneen Schaeffer
Dissertations and Theses (Open Access)

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CHARACTERIZING A NOVEL GENETIC LOCUS ASSOCIATED WITH FAMILIAL CO-OCCURRENCE OF THORACIC AORTIC ANEURYSMS AND INTRACRANIAL ANEURYSMS, Alexander H. Li
Dissertations and Theses (Open Access)

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Factors Associated with Early Versus Late Development of Breast and Ovarian Cancer in BRCA1 and BRCA2 Positive Women, Justine M. Cooper
Dissertations and Theses (Open Access)

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Attitudes of Parents at risk of inheriting Li-Fraumeni Syndrome towards predictive genetic testing in their minor-aged children., Leslie A. Newman
Dissertations and Theses (Open Access)

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A NEW TUMOR SUPPRESSOR GENE CANDIDATE REGULATED BY THE NON-CODING RNA PCA3 IN HUMAN PROSTATE CANCER, Alessandro K. Lee
Dissertations and Theses (Open Access)

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DAMAGE-INDUCED INFLAMMATION AND NOCICEPTIVE HYPERSENSITIVITY IN DROSOPHILA LARVAE, Daniel T. Babcock
Dissertations and Theses (Open Access)

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VALIDATION OF THE ACTIVATION OF AURORA B KINASE BY CAENORHABDITIS ELEGANS TOUSLED-LIKE KINASE AND THE IDENTIFICATION OF CYCLIN B3 AS A PHOSPHO-SPECIFIC TLK-1 INTERACTOR, Gary Michael Deyter
Dissertations and Theses (Open Access)

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Xenobiotic Metabolism Genes and Clubfoot, Amy M. Sommer
Dissertations and Theses (Open Access)

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THE CONSEQUENCES OF DISRUPTING THE MDM2-P53 BALANCE IN HEMATOPOIESIS, Hussein A. Abbas
Dissertations and Theses (Open Access)

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Analysis of Variation in Clubfoot Candidate Genes, Audrey R. Ester
Dissertations and Theses (Open Access)

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2005

Esx1 dosage impacts reproductive fitness: Effects on viability and fertility, Laurel E. Fohn
Dissertations and Theses (Open Access)