DigitalCommons@TMC

Genetic analysis of crossover defective mouse spermatocytes reveals discrete crossover precursor intermediates, Tolkappiyan Prem Kumar
Dissertations and Theses (Open Access)

Uncovering Molecular Targets to Overcome Immunosuppression in Non-Small Cell Lung Cancer with Acquired TKI Resistance, Sonia A. Patel
Dissertations and Theses (Open Access)

ANKYRIN DEPENDENT MITOCHONDRIAL FUNCTION AND BIOENERGETICS IN THE HEART, Janani Subramaniam, Janani Subramaniam
Dissertations and Theses (Open Access)

MED12 Is A Critical Regulator of Neural Crest Lineage and Nervous System Myelination, FATMA BETUL AKSOY YASAR
Dissertations and Theses (Open Access)

Risk-Factor induced changes in the Breast Microenvironment facilitate Inflammatory Breast Cancer Progression and Lymphovascular Invasion, Wintana Balema, Wintana Balema
Dissertations and Theses (Open Access)

A molecular and in vivo investigation of advanced prostate cancer: Deconstructing AMPK activity and developing an improved mouse model, Sandi Wilkenfeld
Dissertations and Theses (Open Access)

Non-Photic Mechanisms of Entrainment in BMAL1 Deficient Conditions, Jamie Tran
Dissertations and Theses (Open Access)

Yap and Taz are Required for Neural Crest-Derived Cardiovascular Development, Shannon Erhardt
Dissertations and Theses (Open Access)

HAPLOTYPE-INFORMED ALLELIC IMBALANCE DETECTION FROM RNA IN CANCER, Zuhal Ozcan
Dissertations and Theses (Open Access)

Investigation of Genomic Instability Induced by G-Quadruplexes in the Absence of Functional Topoisomerase 1 in Yeast, Alexandra Berroyer
Dissertations and Theses (Open Access)

COMPUTATIONAL APPROACHES TO UNDERSTAND CHEMORESISTANCE & TUMOR EVOLUTION USING LONGITUDINAL CLINICAL DATA AND LINEAGE TRACING, Sahil Seth
Dissertations and Theses (Open Access)

Invisible Disabilities, Academic Capital and Competitiveness of Genetic Counseling Applicants, Natalie E. Stoner, Meagan Choates, Carla McGruder, Debra Murray, Theresa Wittman, Sara Wofford, Claire N. Singletary
Dissertations and Theses (Open Access)

Modulation of KRAS Structure and Dynamics by KRAS Ubiquitination and Membrane Depolarization, Vinay Nair
Dissertations and Theses (Open Access)

Mutant KRAS Alters Extracellular Vesicle MicroRNA Sorting in Pancreatic Cystic Neoplasms, Rachel L. Dittmar
Dissertations and Theses (Open Access)

Unveiling global roles of G-quadruplexes and G4-22 in human genetics, Ruth Barros De Paula
Dissertations and Theses (Open Access)

The Importance of DNA Repair Capacity to (and a Model to Predict) Cell Radiosensitivity to Ions, David B. Flint, David B. Flint
Dissertations and Theses (Open Access)

MOLECULAR DRIVERS OF BLADDER CANCER MOTILITY, Bryan Wehrenberg
Dissertations and Theses (Open Access)

BIASES AND BLIND-SPOTS IN GENOME-WIDE CRISPR-CAS9 KNOCKOUT SCREENS, Merve Dede
Dissertations and Theses (Open Access)

Fibroblast Heterogeneity in Pancreatic Cancer Immunity, Josephine Darpolor
Dissertations and Theses (Open Access)

SINE OCULIS HOMEOBOX HOMOLOG 1 (SIX1) PLAYS A CRITICAL ROLE IN THE PROGRESSION OF PULMONARY FIBROSIS., Cory Wilson
Dissertations and Theses (Open Access)

Mutations Within and Between Early Cell Division Proteins and Their Effects on Division Regulation in Escherichia coli, Kara Schoenemann
Dissertations and Theses (Open Access)

UNDERSTANDING INTERCELLULAR SIGNALING DURING LUNG INJURY-REPAIR, Margo Patricia Cain
Dissertations and Theses (Open Access)

IMPACT OF EPA AND DHA SUPPLEMENTATION AND 15-LOX-1 EXPRESSION ON COLITIS AND COLITIS-ASSOCIATED COLORECTAL CANCER, Jonathan Jaoude
Dissertations and Theses (Open Access)

Uncovering the ZEB1 Interactome to Identify Novel Regulators of Metastatic Non-small Cell Lung Cancer, Roxsan Manshouri
Dissertations and Theses (Open Access)

THE ROLE OF MEMBRANE DOMAINS IN PROTEIN AND LIPID SORTING DURING ENDOCYTIC TRAFFIC, Blanca B. Diaz-Rohrer
Dissertations and Theses (Open Access)

Investigating the role of CD109 in Pancreatic Ductal Adenocarcinoma, MennatAllah Shaheen
Dissertations and Theses (Open Access)

OBSCURIN MEDIATES ANKYRIN COMPLEX FORMATION IN THE HEART, Janani Subramaniam
Dissertations and Theses (Open Access)

ROLE OF c-MET and EGFR IN ACQUIRED RESISTANCE TO PARP INHIBITORS IN TRIPLE-NEGATIVE BREAST CANCER, Clinton Yam
Dissertations and Theses (Open Access)

Higher order chromosome organization and recombination dynamics of meiotic prophase I in mouse spermatocytes, Rhea Kang
Dissertations and Theses (Open Access)

Cross-presentation Is A Source of Tumor Antigens For Multiple Myeloma Immunotherapy, Alexander A. Perakis
Dissertations and Theses (Open Access)

Thiol-based Misfolding: Linking Redox Balance to Cytosolic Proteostasis, Ford Amy
Dissertations and Theses (Open Access)

Data collection curated with an application ontology describes the methods and results upon performing an ex-vivo voltage-clamp assay on outer hair cells of the mammalian cochlea, Brenda Farrell, Jason Bengtson
BCM Research Data

The Role of Tumor Suppressor DEAR1 in the Acquisition of Mammary Stem/Progenitor Cell Properties, Uyen Le
Dissertations and Theses (Open Access)

MICRORNA FUNCTIONS IN UV-INDUCED CUTANEOUS SQUAMOUS CELL CARCINOMA, Tran Nguyen
Dissertations and Theses (Open Access)

The Role of Perivascular FIbrosis in Post-Stroke Glymphatic Impairment and Cerebral Amyloid Angiopathy, Matthew D. Howe
Dissertations and Theses (Open Access)

The Role of Merlin and Apicobasal Polarity in Endometrial Development and Homeostasis, Erin Lopez
Dissertations and Theses (Open Access)

CHARACTERIZATION OF NOTCH1 AND PI3K-PTEN-AKT/mTOR PATHWAY INTERACTION IN HEAD AND NECK SQUAMOUS CELL CARCINOMA, Kyriante' Henry
Dissertations and Theses (Open Access)

INSIGHTS INTO THE THERAPEUTIC POTENTIAL OF SALT INDUCIBLE KINASE 1: A NOVEL MECHANISM OF METABOLIC CONTROL, Randi Fitzgibbon
Dissertations and Theses (Open Access)

CLINICAL AND THERAPEUTIC SIGNIFICANCE OF OBESITY IN MELANOMA, Jennifer L. McQuade
Dissertations and Theses (Open Access)

INVOLVEMENT OF THE RECEPTOR FOR ADVANCED GLYCATION END PRODUCTS (RAGE) IN PROGRESSION OF PANCREATIC CANCER, Nancy Azizian MS
Dissertations and Theses (Open Access)

MECHANISMS UNDERLYING THE SENSITIVITY AND RESISTANCE OF GASTRIC CANCER CELLS TO MET INHIBITORS, Rebecca Schroeder
Dissertations and Theses (Open Access)

LBPI: A WEB INTERFACE FOR THE IDENTIFICATION OF ALLOSTERIC LIGAND BINDING SITES, Nabina Paudyal
Dissertations and Theses (Open Access)

CHARACTERIZATION OF THE UBIQUITIN LIGASE, UBE4B, IN ENDOCYTIC TRAFFICKING, Natalie Sirisaengtaksin, Natalie Sirisaengtaksin
Dissertations and Theses (Open Access)

The Role of the DIRAS Family Members in Regulating Ras Function, Cancer Growth and Autophagy, Margie Nicole Sutton
Dissertations and Theses (Open Access)

PROTEOMIC IDENTIFICATION OF HISTONE POST-TRANSLATIONAL MODIFICATIONS INDUCED BY DNA DOUBLE-STRAND BREAKS AND NOVEL PROTEINS INVOLVED IN THE DNA DAMAGE RESPONSE, Pingping Wang
Dissertations and Theses (Open Access)

TARGETING APOPTOTIC PATHWAYS TO OVERCOME DRUG RESISTANCE IN ACUTE MYELOID LEUKEMIA, Rongqing Pan
Dissertations and Theses (Open Access)

MICROENVIRONMENT-INDUCED PTEN LOSS BY EXOSOMAL MICRORNA PRIMES BRAIN METASTASIS OUTGROWTH, Lin Zhang
Dissertations and Theses (Open Access)

GENOMIC DRIVERS OF CUTANEOUS SQUAMOUS CELL CARCINOMA DEVELOPMENT, Vida Chitsazzadeh
Dissertations and Theses (Open Access)

THE NOTCH TARGET HES4 PROMOTES OSTEOSARCOMA TUMOR GROWTH AND METASTASIS BY INHIBITING OSTEOGENIC DIFFERENTIATION, AND HAS POTENTIAL AS A PROGNOSTIC BIOMARKER FOR NEWLY DIAGNOSED PATIENTS WITH HIGH GRADE OSTEOSARCOMA., Madonna McManus
Dissertations and Theses (Open Access)

Normal Glycolytic Enzyme Activity is Critical for Hypoxia Inducible Factor-1a Activity and Provides Novel Targets for Inhibiting Tumor Growth, Geoffrey Grandjean PhD
Dissertations and Theses (Open Access)

GATING MECHANISMS OF THE CANONICAL TRP CHANNEL ISOFORM TRPC4, Dhananjay P. Thakur
Dissertations and Theses (Open Access)

Investigating the Interaction of AURKA and UBE2C in Colorectal Cancer Cells, Apurva M. Hegde
Dissertations and Theses (Open Access)

ATP-citrate lyase links cyclin E to cellular metabolism in breast cancer, Kim Lucenay
Dissertations and Theses (Open Access)

IGFBP2 POTENTIATES EGFR-STAT3 SIGNALING IN GLIOMA, Yingxuan Chua
Dissertations and Theses (Open Access)

ACTIONS OF PI3K-DELTA INHIBITOR, IDELALISIB, AND ITS COMBINATION WITH BENDAMUSTINE IN CHRONIC LYMPHOCYTIC LEUKEMIA, Prexy Modi
Dissertations and Theses (Open Access)

UNDERSTANDING THE ROLE OF SUMOYLATION IN REGULATING LKB1 FUNCTION, Joan W. Ritho
Dissertations and Theses (Open Access)

REST REGULATORY CIRCUIT CONTROLS DISTINCT ONCOGENIC PROPERTIES OF GLIOBLASTOMA STEM CELLS THROUGH SPECIFIC MICRORNAs, Anantha L Marisetty
Dissertations and Theses (Open Access)

TARGETING COX-2 AND RANK IN AGGRESSIVE BREAST CANCERS: INFLAMMATORY BREAST CANCER AND TRIPLE-NEGATIVE BREAST CANCER, Monica E. Reyes
Dissertations and Theses (Open Access)

The Role of MIR-34a in Inhibition of Prostate Tumor Growth in the bone and Induction of Autophagy, Sanchaika Gaur
Dissertations and Theses (Open Access)

ROLE OF PHOSPHORYLATION OF FOCAL ADHESION KINASE AT TYROSINE 861 IN PROSTATE CANCER METASTASIS, Tanushree Chatterji
Dissertations and Theses (Open Access)

TARGETING COX-2 AND RANK IN AGGRESSIVE BREAST CANCERS: INFLAMMATORY BREAST CANCER AND TRIPLE-NEGATIVE BREAST CANCER, Monica Elizabeth Reyes
Dissertations and Theses (Open Access)

DISCOVERY AND ELUCIDATION OF THE FGFR3-TACC3 RECURRENT FUSION IN GLIOBLASTOMA, Brittany C. Parker Kerrigan
Dissertations and Theses (Open Access)

Strategies to sensitize bladder cancer cells to small molecule inhibitors targeting the PI3K pathway, Giovanni Nitti
Dissertations and Theses (Open Access)

Genomic Characterization of Polyps in Familial Adenomatous Polyposis Patients and Identification of Candidate Chemopreventive Drugs, Francis A. San Lucas
Dissertations and Theses (Open Access)

DEVELOPMENT OF CHIMERIC TYPE IV SECRETION SYSTEMS FOR TRANSFER OF HETEROLOGOUS SUBSTRATES ACROSS THE GRAM-NEGATIVE CELL ENVELOPE, Trista M. Berry
Dissertations and Theses (Open Access)

THE ROLE OF TRAF6 PHOSPHORYLATION IN Src/TRAF6-MEDIATED IKK, JNK, Akt ACTIVATION AND TUMORIGENESIS, Yun Seong Jeong
Dissertations and Theses (Open Access)

CHARACTERIZATION OF FTSA-FTSN INTERACTION DURING ESCHERICHIA COLI CELL DIVISION, kimberly.busiek@gmail.com K. Busiek
Dissertations and Theses (Open Access)

THE EPIGENETICS OF SMALL CELL PROSTATE CANCER, Brittany N. Kleb
Dissertations and Theses (Open Access)

Gain-of-function Mouse Models to Investigate Biological Roles of PRMT6, Alessandra Di Lorenzo
Dissertations and Theses (Open Access)

p53 MAINTAINS HEPATIC CELL IDENTITY DURING LIVER REGENERATION, Zeynep Hande Coban Akdemir
Dissertations and Theses (Open Access)

REGULATION OF MAMMARY GLAND DEVELOPMENT AND TUMORIGENESIS BY 14-3-3 ZETA, Sumaiyah Rehman
Dissertations and Theses (Open Access)

STRUCTURE BASED PREDICTION OF DRUG-PROTEIN INTERACTIONS AT ALLOSTERIC SITES: TOWARDS DIRECT INHIBITION OF THE RAS ONCOGENE, Harrison Hocker
Dissertations and Theses (Open Access)

NATURAL AND EXOGENOUS GENOME EDITING IN WISKOTT-ALDRICH SYNDROME PATIENT CELLS, Tamara J. Laskowski
Dissertations and Theses (Open Access)

THE STAPHYLOCOCCUS PSEUDINTERMEDIUS ADHESIN SPSD CONTAINS A CENTRAL FIBRONECTIN-BINDING DOMAIN, Andrea S. Bordt
Dissertations and Theses (Open Access)

Characterization of Jak, STAT, and Src interactions in Head and Neck Squamous Cell Carcinoma, Reshma Jaseja, Reshma Jaseja
Dissertations and Theses (Open Access)

PRKCa: Identification of a Novel Downstream Target of WT1, Devin Jones
Dissertations and Theses (Open Access)

INVESTIGATING THE ROLES OF THE p63 ISOFORMS IN THE MICRORNA BIOGENESIS PATHWAY, Deepavali Chakravarti
Dissertations and Theses (Open Access)

Acceleration of the PanIN Development in Mice Expressing Oncogenic K-Ras Due to a High Fat Diet, Bincy Philip
Dissertations and Theses (Open Access)

TET1: A UNIQUE DNA DEMETHYLASE FOR MAINTENANCE OF DNA METHYLATION PATTERN, CHUNLEI JIN
Dissertations and Theses (Open Access)

MUTATIONS IN STAT3 ASSOCIATED WITH HUMAN HYPER IgE SYNDROME ENHANCE NFκB AND MAPK-MEDIATED GENE EXPRESSION, Nathaniel Greeley
Dissertations and Theses (Open Access)

A STUDY ON THE FUNCTION OF 14-3-3SIGMA IN REGULATING CANCER ENERGY METABOLISM, Liem M. Phan, Liem M. Phan
Dissertations and Theses (Open Access)

Platelets and Anti-Angiogenic Resistance in Ovarian Carcinoma, Justin N. Bottsford-MIller
Dissertations and Theses (Open Access)

REGULATION OF TOXIN SYNTHESIS BY CLOSTRIDIUM DIFFICILE, Charles Darkoh
Dissertations and Theses (Open Access)

Chronic stress promotes tumor growth through increased BDNF production and neo-innervation, Julie K. Allen
Dissertations and Theses (Open Access)

MicroRNA Regulation of Prostate Cancer Stem/Progenitor Cells and Prostate Cancer Development, Can Liu
Dissertations and Theses (Open Access)

THE HISTONE DEACETYLASE INHIBITOR, MS-275, SENSITIZES METASTATIC OSTEOSARCOMA TO FASL-INDUCED CELL DEATH: A ROLE FOR C-FLIP, Krithi R. Bindal
Dissertations and Theses (Open Access)

Increased geranylgeranylated K-Ras contributes to antineoplastic effects of farnesyltransferase inhibitors., Mandy A. Hall
Dissertations and Theses (Open Access)

THE ROLE OF RECEPTOR TYROSINE KINASE AXL IN PANCREATIC DUCTAL ADENOCARCINOMA AND ITS REGULATION BY HEMATOPOIETIC PROGENITOR KINASE 1, Xianzhou Song
Dissertations and Theses (Open Access)

A Cell Biological Determination of Integrator Subunit Localization, Sarah B. May
Dissertations and Theses (Open Access)

Significance of Increased Tissue Transglutaminase in Hormone Refractory Prostate Cancer, Amy L. Han
Dissertations and Theses (Open Access)

STUDY OF REST AS A NEGATIVE REGULATOR OF P16INK4A, Monica B. Gireud
Dissertations and Theses (Open Access)

Upregulation of Reactive Oxygen Species During the Retrovirus Life Cycle and Their Roles in a Mutant of Moloney Murine Leukemia Virus, ts1-Mediated Neurodegeneration, SOO JIN KIM
Dissertations and Theses (Open Access)

DOWNREGULATION OF PAX2 SUPPRESSES OVARIAN CANCER CELL GROWTH, huijuan song
Dissertations and Theses (Open Access)

ROLE OF PROSTAGLANDIN E2 IN THE REGULATION OF PANCREATIC STELLATE CELLS HYPER ACTIVITY ASSOCIATED WITH PANCREATIC CANCER, Chantale Charo
Dissertations and Theses (Open Access)

Dissecting the Interaction between p53 and TRIM24, Aundrietta D. Duncan
Dissertations and Theses (Open Access)

THE ROLE OF CYCLIN E IN PKC IOTA-DRIVEN EARLY OVARIAN TUMORIGENESIS, Angela Nanos-Webb
Dissertations and Theses (Open Access)

COP 9 SIGNALOSOME SUBUNIT 6 STABILIZES COP1, A NOVEL E3 UBIQUITIN LIGASE FOR 14-3-3σ, Hyun Ho Choi
Dissertations and Theses (Open Access)

Investigating the Effects of Silencing EphA2 in Metastatic Breast Cancer Cells, Stephanie Erzinger
Dissertations and Theses (Open Access)

PLASMACYTOID DENDRITIC CELLS SENSE SKIN INJURY AND PROMOTE WOUND HEALING THROUGH TYPE I INTERFERONS, Josh D. Gregorio
Dissertations and Theses (Open Access)

14-3-3SIGMA NEGATIVELY REGULATES THE STABILITY AND SUBCELLULAR LOCALIZATION OF COP1, Chun-Hui Su
Dissertations and Theses (Open Access)

MODELING SPORADIC TUMOR FORMATION DRIVEN BY TELOMERE DYSFUNCTION IN THE GASTROINTESTINAL TRACT, Suzanne S. Chan
Dissertations and Theses (Open Access)

A METAGENOMIC STUDY OF THE TICK MIDGUT, Daniel T. Yuan
Dissertations and Theses (Open Access)

NEW TARGET GENES FOR TUMOR SUPPRESSORS p53 AND p73 IN REGENERATING LIVER, Svitlana M. Kurinna
Dissertations and Theses (Open Access)

A NEW TUMOR SUPPRESSOR GENE CANDIDATE REGULATED BY THE NON-CODING RNA PCA3 IN HUMAN PROSTATE CANCER, Alessandro K. Lee
Dissertations and Theses (Open Access)

Myogenin modulates exercise endurance by altering skeletal muscle metabolism, james eric meadows
Dissertations and Theses (Open Access)

GSK3 Mediates Signaling Upstream of Akt, Debra L. Smith
Dissertations and Theses (Open Access)

THE CONSEQUENCES OF DISRUPTING THE MDM2-P53 BALANCE IN HEMATOPOIESIS, Hussein A. Abbas
Dissertations and Theses (Open Access)

PREECLAMPSIA, AUTOIMMUNITY AND THE AT1 RECEPTOR, Roxanna A. Irani
Dissertations and Theses (Open Access)