Part of the Cell and Developmental Biology Commons

Works in Cell and Developmental Biology

2023

Regulation and Function of ZEB1 Acetylation in Lung Adenocarcinoma Progression and Metastasis, Mabel Perez-Oquendo
Dissertations and Theses (Open Access)

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UNIQUE TRANSCRIPTIONAL PROFILES UNDERLIE OSTEOSARCOMAGENESIS DRIVEN BY DIFFERENT p53 MUTANTS, Dhruv Chachad
Dissertations and Theses (Open Access)

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Regulation of de novo and Maintenance DNA Methylation by DNMT3A and DNMT3B, Yang Zeng
Dissertations and Theses (Open Access)

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Elucidating mechanisms involved in host microbial-tumor interactions, Vidhi Chandra
Dissertations and Theses (Open Access)

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TARGETING METABOLIC ALTERATIONS ASSOCIATED WITH SMOOTH MUSCLE α-ACTIN PATHOGENIC VARIANT ATTENUATES MOYAMOYA-LIKE CEREBROVASCULAR DISEASE, Anita Kaw
Dissertations and Theses (Open Access)

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KIR-BASED INHIBITORY CARS OVERCOME CAR-NK CELL TROGOCYTOSIS-MEDIATED FRATRICIDE AND TUMOR ESCAPE, YE NMN LI
Dissertations and Theses (Open Access)

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Adipocytes and Innate Immunity in Systemic Sclerosis, Nancy Wareing
Dissertations and Theses (Open Access)

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Uncovering Molecular Targets to Overcome Immunosuppression in Non-Small Cell Lung Cancer with Acquired TKI Resistance, Sonia A. Patel
Dissertations and Theses (Open Access)

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P53 DIMERS ELICIT UNIQUE TUMOR SUPPRESSIVE ACTIVITIES THROUGH AN ALTERED METABOLIC PROGRAM, Jovanka Gencel-Augusto
Dissertations and Theses (Open Access)

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PRECLINICAL EVALUATION OF IMMUNOMODULATORY EFFECTS OF AURORA KINASE INHIBITION IN HUMAN PAPILLOMAVIRUS POSITIVE CANCERS, Pragya Sinha
Dissertations and Theses (Open Access)

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HYPOXIA ACTIVATED PRODRUG AND ANTI-ANGIOGENIC THERAPY COOPERATE TO TREAT PANCREATIC CANCER BUT ELICIT IMMUNE SUPPRESSIVE G-MDSC INFILTRATION, Arthur Liu
Dissertations and Theses (Open Access)

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Y CHROMOSOME GENE KDM5D EPIGENETICALLY DRIVES SEX DIFFERENCES IN COLORECTAL CANCER, Jiexi Li
Dissertations and Theses (Open Access)

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FUNCTIONAL ANALYSIS OF DAXX IN TUMORIGENESIS OF PANCREATIC NEUROENDOCRINE TUMORS AND EMBRYONIC DEVELOPMENT, Chang Sun
Dissertations and Theses (Open Access)

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Genetic Regulation of Müllerian Duct Regression, Malcolm Moses
Dissertations and Theses (Open Access)

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Potentiation of the Immune Checkpoint Blockade Response by Metabolic Modulation is Predictable using Molecular Imaging, Renee L. Chin
Dissertations and Theses (Open Access)

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Low molecular weight cyclin E deregulates DNA replication and damage repair to promote genomic instability in breast cancer, Mi Li
Dissertations and Theses (Open Access)

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S-Acylation is a Key Regulator of Orai1/STIM1-Mediated Store-Operated Calcium Entry in T Cells, Savannah J. West Diaz
Dissertations and Theses (Open Access)

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2022

ANKYRIN DEPENDENT MITOCHONDRIAL FUNCTION AND BIOENERGETICS IN THE HEART, Janani Subramaniam, Janani Subramaniam
Dissertations and Theses (Open Access)

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MED12 Is A Critical Regulator of Neural Crest Lineage and Nervous System Myelination, FATMA BETUL AKSOY YASAR
Dissertations and Theses (Open Access)

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The ADAR-MAVS pathway is a critical mediator of the innate immune system in pancreatic development and cancer, Dhwani Rupani
Dissertations and Theses (Open Access)

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Non-Photic Mechanisms of Entrainment in BMAL1 Deficient Conditions, Jamie Tran
Dissertations and Theses (Open Access)

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Roles of oxidative stress and DNA methylation in cigarette smoking-induced accelerated acute myeloid leukemia progression, Mary Figueroa
Dissertations and Theses (Open Access)

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The Role of the Hypoxia-Inducible Factor 2 in Pancreatic Cancer: Mechanisms of Tumor Immunosuppression and Intestinal Radioprotection, Carolina Garcia Garcia
Dissertations and Theses (Open Access)

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Yap and Taz are Required for Neural Crest-Derived Cardiovascular Development, Shannon Erhardt
Dissertations and Theses (Open Access)

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Genomewide CRISPR/Cas9 Screen Identifies Network of Protein Complexes that Regulate TRIM24, Lalit Patel
Dissertations and Theses (Open Access)

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GRK3 CONNECTS ANGIOGENESIS AND NEUROENDOCRINE DIFFERENTIATION IN PROSTATE CANCER BY ACTIVATING HDAC2 THAT EPIGENETICALLY REPRESSES TSP1 AND REST, Samira Naderinezhad
Dissertations and Theses (Open Access)

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Integrin-Mediated Mechanotransduction Controls Activation of YAP and Invasive Growth of Breast Cancer, Xiaobo Wang
Dissertations and Theses (Open Access)

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The Novel Role of Dnmbp in Kidney Development, Brandy Walker
Dissertations and Theses (Open Access)

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Regulation of systemic and cellular metabolism in prostate cancer by CAMKK2 and elucidation of ATGL’s role in disease progression, Dominik Awad
Dissertations and Theses (Open Access)

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Development and Characterization of B7-H3-Targeted Radioimmunotherapies for the Treatment of Solid Tumors, Sarah Glazer
Dissertations and Theses (Open Access)

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INTEGRATION OF BIOMEDICAL IMAGING AND TRANSLATIONAL APPROACHES FOR MANAGEMENT OF HEAD AND NECK CANCER, Abdallah Mohamed, Abdallah Mohamed
Dissertations and Theses (Open Access)

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NOVEL REGULATORS OF CELLULAR SECRETION ALTER THE TUMOR MICROENVIRONMENT TO DRIVE METASTASIS, Rakhee Bajaj
Dissertations and Theses (Open Access)

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Modulation of KRAS Structure and Dynamics by KRAS Ubiquitination and Membrane Depolarization, Vinay Nair
Dissertations and Theses (Open Access)

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EXPLOITING CHEMOGENETIC AND GENETIC INTERACTIONS IN HUMAN CELLS AS AN AVENUE FOR NEW THERAPEUTIC OPPORTUNITIES, Medina Colic
Dissertations and Theses (Open Access)

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An Investigation of Epigenetic Mechanisms Driving the Biology of Head and Neck Squamous Cell Carcinoma, Scot Carson Callahan
Dissertations and Theses (Open Access)

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Plant Homeodomain Finger Protein 20 (PHF20) and its Homolog PHF20 Like 1 (PHF20L1) Define Two Distinct Non-Specific Lethal (NSL) Complexes, Hieu Van, Hieu T. Van
Dissertations and Theses (Open Access)

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2021

LGR5 Regulation of STAT3 Signaling and Drug Resistance in Colorectal Cancer, Tressie Posey, Tressie Alexandra Posey
Dissertations and Theses (Open Access)

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INVESTIGATING THERAPEUTIC STRATEGIES TO TARGET METABOLIC VULNERABILITIES OF NSCLC TUMORS WITH MUTANT KEAP1 GENE, Pranavi Koppula
Dissertations and Theses (Open Access)

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4D EX VIVO CRISPR/CAS9 WHOLE-GENOME SCREEN TO IDENTIFY GENES REGULATING LUNG CANCER METASTASIS, Alexandria Plumer
Dissertations and Theses (Open Access)

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STAT3 INHIBITS TYPE I INTERFERON SIGNALING IN TYPE I CONVENTIONAL DENDRITIC CELLS, Taylor Chrisikos
Dissertations and Theses (Open Access)

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Mutant KRAS Alters Extracellular Vesicle MicroRNA Sorting in Pancreatic Cystic Neoplasms, Rachel L. Dittmar
Dissertations and Theses (Open Access)

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ATRX INACTIVATION AND IDH1-R132H DRIVE PREFERENTIAL SENSITIVITY TO PROTON VS. X-RAY RADIOTHERAPY IN GLIOMA STEM CELLS, Ángel Adrián Garcés
Dissertations and Theses (Open Access)

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Targeting Plasma Membrane Phosphatidylserine Content to Inhibit Oncogenic KRAS Function, Walaa E. Kattan
Dissertations and Theses (Open Access)

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NPSD4: A NEW PLAYER IN SUMO-DEPENDENT DNA REPAIR, Erin Atkinson
Dissertations and Theses (Open Access)

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REGULATION OF LUNG MESENCHYMAL CELLS BY EPITHELIAL WNT LIGANDS, Odemaris Narvaez del Pilar
Dissertations and Theses (Open Access)

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Understanding the Pathogenesis of Renal Medullary Carcinoma, Melinda Soeung
Dissertations and Theses (Open Access)

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EPITHELIAL MEMORY OF RESOLVED INFLAMMATION LIMITS TISSUE DAMAGE WHILE PROMOTING PANCREATIC TUMORIGENESIS, I-Lin Ho
Dissertations and Theses (Open Access)

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Combination of Oncolytic Adenoviruses, T-cell Activation, and Blockade of IDO Metabolic Circuitry for the Treatment of Glioma, Teresa Nguyen
Dissertations and Theses (Open Access)

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The Functional Analysis of a Major Tyrosine Phosphorylation Site on Actin, Amelie Simone Cordelia Albrecht
Dissertations and Theses (Open Access)

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Genetic Pathway Analysis of Abnormal Facial Development in Nonsyndromic Cleft Lip and Palate, lorena maili
Dissertations and Theses (Open Access)

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Assessing the Outcomes of Blocking CCL2-CCR2 Signaling Axis on Breast Cancer Brain Metastasis, Yutao Qi
Dissertations and Theses (Open Access)

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The Role of PAG1 in the Activated B-Cell Subtype of Diffuse Large B-Cell Lymphoma, Jared Henderson
Dissertations and Theses (Open Access)

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2020

QKI-MEDIATED CHOLESTEROL BIOSYNTHESIS IN EYE LENS AND MYELIN OF THE CENTRAL NERVOUS SYSTEM, Seula Shin, Seula Shin
Dissertations and Theses (Open Access)

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Fibroblast Heterogeneity in Pancreatic Cancer Immunity, Josephine Darpolor
Dissertations and Theses (Open Access)

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THE ROLE OF DAAM1 IN KIDNEY DEVELOPMENT, vanja krneta-stankic
Dissertations and Theses (Open Access)

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Subclonal evolution of chronic lymphocytic leukemia after allogeneic T cell therapies, Haven Garber
Dissertations and Theses (Open Access)

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SINE OCULIS HOMEOBOX HOMOLOG 1 (SIX1) PLAYS A CRITICAL ROLE IN THE PROGRESSION OF PULMONARY FIBROSIS., Cory Wilson
Dissertations and Theses (Open Access)

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THE ROLE OF DAAM1 IN KIDNEY DEVELOPMENT, vanja krneta-stankic
Dissertations and Theses (Open Access)

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MICRORNAs ASSOCIATED WITH MELANOMA INFLAMMATION AND RESPONSE TO PD-1 INHIBITION, Robert Szczepaniak Sloane
Dissertations and Theses (Open Access)

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PACKAGING AND SECRETION OF AIRWAY MUCINS, Oanh Ngoc Hoang
Dissertations and Theses (Open Access)

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Calcium Dyshomeostasis in Neurodegeneration, Nicholas Emanuel Karagas
Dissertations and Theses (Open Access)

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QKI-MEDIATED CHOLESTEROL BIOSYNTHESIS IN EYE LENS AND MYELIN OF THE CENTRAL NERVOUS SYSTEM, Seula Shin, Seula Shin
Dissertations and Theses (Open Access)

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IONIC MECHANISM OF LYSOSOMAL FUNCTION AND CELL METABOLISM, Jian Xiong
Dissertations and Theses (Open Access)

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p53 drives a transcriptional program that elicits a non-cell-autonomous response and alters cell state in vivo, Sydney Moyer
Dissertations and Theses (Open Access)

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Disruption of DNA Polymerase Zeta Promotes an Innate Immune Response, Sara Martin
Dissertations and Theses (Open Access)

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The Genome-Wide Roles of the Lung Lineage Transcription Factor NKX2-1 in the Regulation of Opposing Cell Fates In Vivo, Danielle Renae Little
Dissertations and Theses (Open Access)

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PUTATIVE ROLES OF CD200 IN THE LEUKEMOGENESIS AND IMMUNE EVASION OF LEUKEMIA STEM CELLS, Shelley Herbrich
Dissertations and Theses (Open Access)

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Artificial intron technology to generate conditional knock-out mice, Amber N. Thomas-Gordon
Dissertations and Theses (Open Access)

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LONGITUDINAL CLONAL LINEAGE DYNAMICS AND FUNCTIONAL CHARACTERIZATION OF PANCREATIC CANCER CHEMO-RESISTANCE AND METASTASIZATION, Chieh-Yuan Li
Dissertations and Theses (Open Access)

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EXOSOMAL COMMUNICATION BY METASTATIC OSTEOSARCOMA CELLS MODULATES ALVEOLAR MACROPHAGES TO AN M2 TUMOR-PROMOTING PHENOTYPE AND INHIBITS TUMORICIDAL FUNCTIONS, Kerri Wolf
Dissertations and Theses (Open Access)

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Heterogeneous Nuclear Ribonucleoprotein K (hnRNP K) Overexpression and its Interaction with RUNX1 RNA in Acute Myeloid Leukemia, Marisa Aitken
Dissertations and Theses (Open Access)

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RECEPTOR TYROSINE KINASES-MEDIATED ACQUIRED PARP INHIBITOR RESISTANCE IN BREAST CANCER, MEI-KUANG CHEN
Dissertations and Theses (Open Access)

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UNDERSTANDING INTERCELLULAR SIGNALING DURING LUNG INJURY-REPAIR, Margo Patricia Cain
Dissertations and Theses (Open Access)

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IMPACT OF EPA AND DHA SUPPLEMENTATION AND 15-LOX-1 EXPRESSION ON COLITIS AND COLITIS-ASSOCIATED COLORECTAL CANCER, Jonathan Jaoude
Dissertations and Theses (Open Access)

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EFFECTS OF PENFLURIDOL ON INTEGRIN-FAK SIGNALING AND TUMOR CELL KILLING IN COMBINATION WITH ONCOLYTIC HSV IN GLIOBLASTOMA, Mitra Nair
Dissertations and Theses (Open Access)

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Effect of sympathetic nervous system mediators on the tumor microenvironment via small extracellular vesicles in ovarian cancer, Sujanitha Umamaheswaran, Sujanitha Umamaheswaran
Dissertations and Theses (Open Access)

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10th Annual Postdoctoral Science Symposium, University of Texas MD Anderson Cancer Center PostDoctoral Association
MD Anderson Cancer Center Postdoctoral Association Annual Postdoctoral Science Symposium Abstracts

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2019

A NOVEL SWITCH-LIKE FUNCTION OF DELTA-CATENIN IN DENDRITE DEVELOPMENT, Ryan Baumert
Dissertations and Theses (Open Access)

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Uncovering the ZEB1 Interactome to Identify Novel Regulators of Metastatic Non-small Cell Lung Cancer, Roxsan Manshouri
Dissertations and Theses (Open Access)

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THE ROLE OF MEMBRANE DOMAINS IN PROTEIN AND LIPID SORTING DURING ENDOCYTIC TRAFFIC, Blanca B. Diaz-Rohrer
Dissertations and Theses (Open Access)

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9th Annual Postdoctoral Science Symposium, University of Texas MD Anderson Cancer Center PostDoctoral Association
MD Anderson Cancer Center Postdoctoral Association Annual Postdoctoral Science Symposium Abstracts

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GCN5 Loss Impacts MYC-Driven Cancer in Mice and Human Cells, Aimee Farria
Dissertations and Theses (Open Access)

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DEUBIQUITINATING ENZYMES PROMOTE CANCER PROGRESSION AND METASTASIS VIA REGULATING PROTEIN STABILITY, Zhenna Xiao
Dissertations and Theses (Open Access)

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FASTING REDUCES INTESTINAL RADIOTOXICITY ENABLING DOSE-ESCALATED RADIOTHERAPY FOR PANCREATIC CANCER, Marimar de la Cruz Bonilla
Dissertations and Theses (Open Access)

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MODELING CANCER USING LI-FRAUMENI SYNDROME PATIENT-DERIVED INDUCED PLURIPOTENT STEM CELLS, Ruoji Zhou
Dissertations and Theses (Open Access)

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IPSC BASED GENE CORRECTION AND DISEASE MODEL OF A NEW CLASS OF LGMD DUE TO POGLUT1 MUTATION, Jose Ortiz-Vitali
Dissertations and Theses (Open Access)

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THE GSK-3β-FBXL21 AXIS REGULATES TCAP VIA UBIQUITIN-MEDIATED PROTEASOMAL PATHWAY IN THE CYTOPLASM, Jiah Yang
Dissertations and Theses (Open Access)

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THE ROLE OF GENE EXPRESSION NOISE IN MAMMALIAN CELL SURVIVAL, Kevin Farquhar
Dissertations and Theses (Open Access)

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IL-6/JAK1 DRIVES PD-L1 PHOSPHORYLATION AND GLYCOSYLATION TO PROMOTE CANCER IMMUNE EVASION, Li-Chuan Chan
Dissertations and Theses (Open Access)

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PLATISCITY OF C. ELEGANS GERMLINE STEM CELLS UNDER NUTRITIONAL AND METABOLIC STRESS, Kenneth Trimmer
Dissertations and Theses (Open Access)

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Cross-presentation Is A Source of Tumor Antigens For Multiple Myeloma Immunotherapy, Alexander A. Perakis
Dissertations and Theses (Open Access)

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AN OXANTHROQUINONE DERIVATIVE DISRUPTS RAS PLASMA MEMBRANE LOCALIZATION AND FUNCTION BY INHIBITION OF ACYLPEPTIDE HYDROLASE AND PERTURBATION OF SPHINGOMYELIN METABOLISM, Lingxiao Tan
Dissertations and Theses (Open Access)

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GENETIC COUNSELOR UTILIZATION AND INTERPRETATION OF SOMATIC TUMOR TESTING IN EVALUATION FOR LYNCH SYNDROME, Danielle Williams
Dissertations and Theses (Open Access)

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Thiol-based Misfolding: Linking Redox Balance to Cytosolic Proteostasis, Ford Amy
Dissertations and Theses (Open Access)

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2018

ROLE OF P300 ZZ DOMAIN IN CHROMATIN ASSOCIATION AND HISTONE ACETYLATION, Yongming Xue
Dissertations and Theses (Open Access)

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8th Annual Postdoctoral Science Symposium, University of Texas MD Anderson Cancer Center PostDoctoral Association
MD Anderson Cancer Center Postdoctoral Association Annual Postdoctoral Science Symposium Abstracts

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UBE4B LEVELS DETERMINE THE EFFICACY OF EGFR AND STAT5 INHIBITORS IN TREATMENT RESISTANT NEUROBLASTOMA, David James Savage
Dissertations and Theses (Open Access)

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SIMVASTATIN DOES NOT SENSITIZE IBC3 HER2+ INFLAMMATORY BREAST CANCER BRAIN METASTASES TO WHOLE BRAIN IRRADIATION IN AN IMMUNOCOMPROMISED MOUSE MODEL, Swaminathan Kumar
Dissertations and Theses (Open Access)

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INVESTIGATING THE ROLES OF TAP63 AND TAP73 IN CUTANEOUS SQUAMOUS CELL CARCINOMA AND LUNG ADENOCARCINOMA, Andrew J. Davis
Dissertations and Theses (Open Access)

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An expanded toolkit for gene tagging based on MiMIC and scarless CRISPR tagging in, David Li-Kroeger, Oguz Kanca, Pei-Tseng Lee, Sierra Cowan, Michael T Lee, Manish Jaiswal, Jose Luis Salazar, Yuchun He, Zhongyuan Zuo, Hugo J Bellen
BCM Faculty Publications

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Characterizing the recognition motif and novel substrates of CARM1, Sitaram gayatri
Dissertations and Theses (Open Access)

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DISSECTING THE MOLECULAR MECHANISM OF EARLY TUMOR DISSEMINATION IN NON-SMALL CELL LUNG CANCER, Xingtong Liu
Dissertations and Theses (Open Access)

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MECHANISMS AND TARGETING OF NEURODEVELOPMENTAL REGULATOR REST IN MEDULLOBLASTOMA DISSEMINATION, Keri Callegari
Dissertations and Theses (Open Access)

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EPITHELIAL TO MESENCHYMAL TRANSITION AS A PREDICTOR OF RESPONSE TO POLO-LIKE KINASE 1 INHIBITION-INDUCED APOPTOSIS IN NON-SMALL CELL LUNG CARCINOMA, Pavitra Viswanath
Dissertations and Theses (Open Access)

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The Regulation of DNA Methylation in Mammalian Development and Cancer, Nicolas Veland
Dissertations and Theses (Open Access)

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IDENTIFICATION AND UTILITY OF DNA IN EXOSOMES, Paul Kurywchak
Dissertations and Theses (Open Access)

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TRIM24 as an Oncogene in the Mammary Gland, Aundrietta Duncan
Dissertations and Theses (Open Access)

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INVESTIGATING INVASION IN DUCTAL CARCINOMA IN SITU WITH TOPOGRAPHICAL SINGLE CELL GENOME SEQUENCING, Anna Casasent, Anna Casasent
Dissertations and Theses (Open Access)

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PHOSPHORYLATION IMPAIRS DICER1 FUNCTION TO ACCELERATE AGING AND TUMORIGENESIS IN VIVO, Neeraj Aryal
Dissertations and Theses (Open Access)

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Trim24 in Normal & Malignant Hematopoiesis, Justin Shaw
Dissertations and Theses (Open Access)

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DECIPHERING THE ROLES OF ΔNP63 IN REGULATING EPITHELIAL TO MESENCHYMAL TRANSITION, CANCER PROGRESSION AND METASTASIS, Ngoc Bui
Dissertations and Theses (Open Access)

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SPHINGOSINE KINASE 1 REGULATES FASCIN EXPRESSION TO PROMOTE METASTASIS IN TRIPLE NEGATIVE BREAST CANCER, Sunil Acharya
Dissertations and Theses (Open Access)

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FUNCTIONAL HETEROGENEITY OF FIBROBLASTS IN DERMAL WOUND HEALING, Ehsan Ehsanipour
Dissertations and Theses (Open Access)

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2017

ENDOCYTIC TRAFFICKING OF THE AMYLOID PRECURSOR PROTEIN IN RAT CORTICAL NEURONS, sahily reyes
Dissertations and Theses (Open Access)

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CHARACTERIZATION OF NOTCH1 AND PI3K-PTEN-AKT/mTOR PATHWAY INTERACTION IN HEAD AND NECK SQUAMOUS CELL CARCINOMA, Kyriante' Henry
Dissertations and Theses (Open Access)

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The functions of SETD5 and miR-221 in embryonic stem cell differentiation, Tsai-Yu Chen
Dissertations and Theses (Open Access)

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INSIGHTS INTO THE THERAPEUTIC POTENTIAL OF SALT INDUCIBLE KINASE 1: A NOVEL MECHANISM OF METABOLIC CONTROL, Randi Fitzgibbon
Dissertations and Theses (Open Access)

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STUDY OF REGULATED CELL DEATH IN TWO SYSTEMS: PD-1 IN NATURAL KILLER CELLS AND RIP3 IN NEURONS, YU HUANG
Dissertations and Theses (Open Access)

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Pharmacologic and Genetic Manipulations of Angiotensin Signaling in Thoracic Aortic Disease Models, Andrew M. Peters
Dissertations and Theses (Open Access)

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Gcn5 Impacts FGF Signaling At Multiple Levels And Activates C-Myc Target Genes During Early Differentiation Of Embryoid Bodies, Li Wang
Dissertations and Theses (Open Access)

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Preclinical Development of Therapeutic Strategies Against Triple-Negative and Inflammatory Breast Cancer, Angie M. Torres-Adorno
Dissertations and Theses (Open Access)

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INVESTIGATING THE ROLE OF PRMT1 AND ARGININE METHYLATION OF HSP70 IN HUMAN PANCREATIC CANCER, Liang Wang
Dissertations and Theses (Open Access)

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WISP1 IS AN OVEREXPRESSED DRIVER OF GLIOBLASTOMA, Pushan R. Dasgupta
Dissertations and Theses (Open Access)

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THE ROLE OF THE EPITHELIAL-TO-MESENCHYMAL TRANSITION (EMT) IN LUNG CANCER PROGRESSION, David H. Peng
Dissertations and Theses (Open Access)

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MECHANISMS UNDERLYING THE SENSITIVITY AND RESISTANCE OF GASTRIC CANCER CELLS TO MET INHIBITORS, Rebecca Schroeder
Dissertations and Theses (Open Access)

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TARGETING AUTOPHAGY TO IMPROVE EFFICACY OF CDK4/6 INHIBITION IN BREAST CANCER, Smruthi Vijayaraghavan
Dissertations and Theses (Open Access)

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PHOPSPHORYLATION AND UBIQUITIN MODIFICATION AT DNA DAMAGE SITES IN RESPONSE TO DOUBLE-STRAND BREAKS, Atanu Paul
Dissertations and Theses (Open Access)

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CHARACTERIZATION OF THE UBIQUITIN LIGASE, UBE4B, IN ENDOCYTIC TRAFFICKING, Natalie Sirisaengtaksin, Natalie Sirisaengtaksin
Dissertations and Theses (Open Access)

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Stromal Fibroblasts Restrain the Rate of Colon Cancer Progression and Metastasis by Suppressing Regulatory T Cells and Colon Cancer Stem Cells, Changsoo Kwak
Dissertations and Theses (Open Access)

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UNDERSTANDING THE MECHANISM OF GENOMIC INSTABILITY DURING REPLICATIVE AGING IN BUDDING YEAST, Sangita Pal
Dissertations and Theses (Open Access)

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NON-CODING RNAS IDENTIFY THE INTRINSIC MOLECULAR SUBTYPES OF MUSCLE-INVASIVE BLADDER CANCER, Andrea E. Ochoa
Dissertations and Theses (Open Access)

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INVESTIGATION OF THE ROLES OF ASF1 AND CAF-1-MEDIATED CHROMATIN ASSEMBLY IN THE HUMAN DNA DAMAGE RESPONSE, Ting-Hsiang Huang
Dissertations and Theses (Open Access)

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ANDROGEN RECEPTOR AND PROSTATE CANCER CELL HETEROGENEITY, Qu Deng
Dissertations and Theses (Open Access)

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The Role of the DIRAS Family Members in Regulating Ras Function, Cancer Growth and Autophagy, Margie Nicole Sutton
Dissertations and Theses (Open Access)

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Cyclin B1 mediates the effect of UCHL1 in promoting cell cycle progression in uterine papillary serous carcinoma, Suet Ying Kwan
Dissertations and Theses (Open Access)

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PARP inhibitor upregulates PD-L1 expression and enhances cancer-associated immunosuppression, Shiping Jiao
Dissertations and Theses (Open Access)

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PROTEOMIC IDENTIFICATION OF HISTONE POST-TRANSLATIONAL MODIFICATIONS INDUCED BY DNA DOUBLE-STRAND BREAKS AND NOVEL PROTEINS INVOLVED IN THE DNA DAMAGE RESPONSE, Pingping Wang
Dissertations and Theses (Open Access)

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THE ROLE OF ADENOSINE SIGNALING IN MATURE ERYTHROCYTES AND ERYTHROID PROGENITORS, Hong Liu
Dissertations and Theses (Open Access)

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MOLECULAR MECHANISMS OF INWARD AND OUTWARD BUDDING FROM MULTIVESICULAR ENDOSOMES, Monica Gireud Goss
Dissertations and Theses (Open Access)

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A rare case of erythema elevatum diutinum presenting as diffuse neuropathy., G H. Nguyen, E L. Guo, D Norris
BCM Faculty Publications

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TARGETING APOPTOTIC PATHWAYS TO OVERCOME DRUG RESISTANCE IN ACUTE MYELOID LEUKEMIA, Rongqing Pan
Dissertations and Theses (Open Access)

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2016

THE ROLE OF STREPTOCOCCUS GALLOLYTICUS SUBSPECIES GALLOLYTICUS IN COLON CANCER DEVELOPMENT, Jennifer L. Herold
Dissertations and Theses (Open Access)

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USING MOUSE MODELS TO DEFINE HOW THE P53 R72P POLYMORPHISM IMPACTS THE ADVERSE EFFECTS OF DOXORUBICIN AND IONIZING RADIATION, Emily Dominguez
Dissertations and Theses (Open Access)

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CONCOMITANT TARGETING OF THE MTOR/MAPK PATHWAYS: NOVEL THERAPEUTIC STRATEGY IN SUBSETS OF NON-SMALL CELL LUNG CANCER, Dennis Ruder
Dissertations and Theses (Open Access)

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MICROENVIRONMENT-INDUCED PTEN LOSS BY EXOSOMAL MICRORNA PRIMES BRAIN METASTASIS OUTGROWTH, Lin Zhang
Dissertations and Theses (Open Access)

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Consensus Paper: Cerebellar Development., K Leto, M Arancillo, EBE Becker, A Chiang, et al.
BCM Faculty Publications

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Characterization of Vesicular Monoamine Transporter 2 and its role in Parkinson's Disease Pathogenesis using Drosophila, Antonio Joel Tito Jr., Sheng Zhang
Dissertations and Theses (Open Access)

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Influence of Maternal Breast Milk Ingestion on Acquisition of the Intestinal Microbiome in Preterm Infants., Katherine E Gregory, Buck S Samuel, Pearl Houghteling, Guru Shan, Frederick M Ausubel, Ruslan I Sadreyev, W Allan Walker
BCM Faculty Publications

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¬¬DEFINE THE EPIGENETIC PROFILES AND SUBTYPE-SPECIFIC GENES OF BREAST CANCER, Wenqian Li
Dissertations and Theses (Open Access)

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REGULATION OF BREAST CANCER INITIATION AND PROGRESSION BY 14-3-3ZETA, Chia-Chi Chang
Dissertations and Theses (Open Access)

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FUNCTION AND MECHANISM OF ALKBH5 IN N6-METHYL-ADENOSINE RNA MODIFICATION IN GLIOBLASTOMA, Sicong Zhang
Dissertations and Theses (Open Access)

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DEFINING THE FUNCTIONS OF USP22 AND USP44 IN REGULATION OF H2BUB1 LEVELS, xianjiang Lan
Dissertations and Theses (Open Access)

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NOVEL MECHANISMS OF β-ADRENERGIC SIGNALING IN PROSTATE CANCER PROGRESSION, Mohit Hulsurkar
Dissertations and Theses (Open Access)

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INVESTIGATING THE ROLES OF ΔNP63 AS A SUPPRESSOR OF MIGRATION, INVASION, AND METASTASIS, Ramon E. Flores Gonzalez
Dissertations and Theses (Open Access)

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GENOMIC DRIVERS OF CUTANEOUS SQUAMOUS CELL CARCINOMA DEVELOPMENT, Vida Chitsazzadeh
Dissertations and Theses (Open Access)

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THE ROLE OF GDF15 IN OVARIAN CANCER, Daisy I. Izaguirre
Dissertations and Theses (Open Access)

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REROUTING PRE-EXISTING HOST VACCINE-INDUCED IMMUNITY TOWARDS BREAST CANCER, Bharat Kumar Reddy Chaganty
Dissertations and Theses (Open Access)

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GSK3BETA-MEDIATED EZH2 PHOSPHORYLATION SUPPRESSES METHYLATION OF H3K27 AND EZH2’S ONCOGENIC FUNCTIONS, How-Wen Ko
Dissertations and Theses (Open Access)

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LIPOCALIN 2 PROMOTES THE ESTABLISHMENT OF A PRO-TUMORIGENIC MICROENVIRONMENT IN PANCREATIC CANCER, Sobeyda B. Gomez-Chou
Dissertations and Theses (Open Access)

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Characterization of Stem Cell Turnover in a Living Epithelial Bilayer, Elizabeth Sumner
Dissertations and Theses (Open Access)

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THE ROLES OF MALT1 IN NF-κB ACTIVATION AND SOLID TUMOR PROGRESSION, Deng Pan
Dissertations and Theses (Open Access)

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Developing and using methyl-specific antibodies to study the biological roles of arginine methylation, Vidyasiri Vemulapalli
Dissertations and Theses (Open Access)

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In Vivo Kinome Screen Reveals Non-canonical CDK-driven Metabolic Adaptation in Brain Metastasis, Frank J. Lowery III
Dissertations and Theses (Open Access)

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TRIM24 orchestrates metabolic reprogramming and EMT in Breast Cancer, Kaushik Thakkar
Dissertations and Theses (Open Access)

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FUNCTIONAL REGULATION OF YAP BY AURORA A KINASE IN TRIPLE-NEGATIVE BREAST CANCER, Shih-Shin Chang
Dissertations and Theses (Open Access)

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THE ROLE OF AMP-ACTIVATED PROTEIN KINASE (AMPK) IN TUMORIGENESIS, Fei Han
Dissertations and Theses (Open Access)

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Comparison of interactive voice response (IVR) with paper administration of instruments to assess functional status, sexual function, and quality of life in elderly men., RC Rosen, AJ Stephens-Shields, GR Cunningham, D Cifelli, D Cella, JT Farrar, E Barrett-Connor, CE Lewis, M Pahor, X Hou, PJ Snyder
BCM Faculty Publications

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Explicit Time Deficit in Schizophrenia: Systematic Review and Meta-Analysis Indicate It Is Primary and Not Domain Specific., V Ciullo, G Spalletta, C Caltagirone, RE Jorge, F Piras
BCM Faculty Publications

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Genome engineering: Drosophila melanogaster and beyond., KJT Venken, A Sarrion-Perdigones, PJ Vandeventer, NS Abel, AE Christiansen, KL Hoffman
BCM Faculty Publications

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CT-based Structural Rigidity Analysis Is More Accurate Than Mirels Scoring for Fracture Prediction in Metastatic Femoral Lesions., TA Damron, A Nazarian, V Entezari, C Brown, W Grant, N Calderon, et al.
BCM Faculty Publications

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Glial Contributions to Neural Function and Disease., MN Rasband
BCM Faculty Publications

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Eosinophilic Esophagitis in Children and Its Relationship with Parental Allergies: Texas Children's Hospital Experience., G Hiremath, D Byramji, A Pacheco, G Constantine, C Davis, R Shulman, A Olive
BCM Faculty Publications

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Efficacy of Psychosocial Interventions in Inducing and Maintaining Alcohol Abstinence in Patients With Chronic Liver Disease: A Systematic Review., A Khan, A Tansel, DL White, WT Kayani, WT Bano, J Lindsay, HB El-Serag, F Kanwal
BCM Faculty Publications

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Early rescue of interneuron disease trajectory in developmental epilepsies., MS Siehr, JL Noebels
BCM Faculty Publications

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Effect of Two-Year Caloric Restriction on Bone Metabolism and Bone Mineral Density in Non-Obese Younger Adults: A Randomized Clinical Trial., DT Villareal, L Fontana, SK Das, et al.
BCM Faculty Publications

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Local Corticotropin Releasing Hormone (CRH) Signals To Its Receptor CRHR1 During Postnatal Development of the Mouse Olfactory Bulb., Isabella Garcia, Paramjit K Bhullar, Burak Tepe, Joshua Ortiz-Guzman, Longwen Huang, Alexander M Herman, Lesley Chaboub, Benjamin Deneen, Nicholas J Justice, Benjamin R Arenkiel
BCM Faculty Publications

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2015

DEFINING THE MOLECULAR NETWORKS NECESSARY FOR THYMUS FATE AND ORGANOGENESIS, Kaitlin A. Reeh
Dissertations and Theses (Open Access)

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PREVENTING THYMUS INVOLUTION IN K5.CYCLIN D1 TRANSGENIC MICE SUSTAINS THE NAÏVE T CELL COMPARTMENT WITH AGE, Michelle L. Bolner
Dissertations and Theses (Open Access)

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ROLE OF STAT3 IN HUMAN NK CELL FUNCTIONS, Prasad V. Phatarpekar
Dissertations and Theses (Open Access)

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Normal Glycolytic Enzyme Activity is Critical for Hypoxia Inducible Factor-1a Activity and Provides Novel Targets for Inhibiting Tumor Growth, Geoffrey Grandjean PhD
Dissertations and Theses (Open Access)

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THE TUMOR SUPPRESSOR NOTCH INHIBITS HEAD AND NECK SQUAMOUS CELL CARCINOMA (HNSCC) TUMOR GROWTH AND PROGRESSION BY MODULATING PROTO-ONCOGENES AXL AND CTNNAL1 (α-CATULIN), Shhyam Moorthy, Shhyam Moorthy
Dissertations and Theses (Open Access)

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MOLECULAR REGULATION OF VASCULAR CALCIFICATION IN MURINE MODELS OF ATHEROSCLEROSIS, Shanshan Gao
Dissertations and Theses (Open Access)

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Mobilization of Adipose Stromal Cells in Obesity and Cancer by SPARC and its Proteolytic Isoforms, Chieh Tseng
Dissertations and Theses (Open Access)

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IDENTIFYING PROTEIN KINASE TBK1 AS A NOVEL INHIBITOR OF INTESTINAL TUMORIGENESIS, Amber L. Mathews
Dissertations and Theses (Open Access)

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Histone H3 K4 methylation regulates the Spindle Assembly Checkpoint through direct binding of multiple checkpoint components and Cdc20, Andria C. Schibler
Dissertations and Theses (Open Access)

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DIRECT REGULATION OF APOPTOSIS BY LINEAR UBIQUTIN CHAIN ASSEMBLY COMPLEX (LUBAC) AND FEEDBACK REGULATION OF LUBAC FUNCTION BY CASPASES, Donghyun Joo
Dissertations and Theses (Open Access)

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MERLIN MEDIATED REGULATION OF HAIR FOLLICLE MORPHOGENESIS, Megan K. Fentress
Dissertations and Theses (Open Access)

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INVESTIGATING THE ROLE OF CHOLESTEROL METABOLISM AND SYNTHESIS IN METASTASIS AND RADIATION RESPONSE IN AGGRESSIVE SUBTYPES OF BREAST CANCER, Adam Wolfe
Dissertations and Theses (Open Access)

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Elucidating the role of Rumi and O-glucosylation in the Drosophila eye, Amanda Haltom
Dissertations and Theses (Open Access)

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SRC HOMOLOGY 2 DOMAIN-CONTAINING 5’-INOSITOL PHOSPHATASE-2 (SHIP2) IS AN EFFECTOR OF LYMPHATIC DYSFUNCTION, Germaine D. Agollah
Dissertations and Theses (Open Access)

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Induction of caspase-dependent death by proteasome targeted therapy in glioblastoma, Christa A. Manton
Dissertations and Theses (Open Access)

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ATP-citrate lyase links cyclin E to cellular metabolism in breast cancer, Kim Lucenay
Dissertations and Theses (Open Access)

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IGFBP2 POTENTIATES EGFR-STAT3 SIGNALING IN GLIOMA, Yingxuan Chua
Dissertations and Theses (Open Access)

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ACTIONS OF PI3K-DELTA INHIBITOR, IDELALISIB, AND ITS COMBINATION WITH BENDAMUSTINE IN CHRONIC LYMPHOCYTIC LEUKEMIA, Prexy Modi
Dissertations and Theses (Open Access)

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IMPACT OF DIFFERENTIATION STATUS OF KIDNEY PROGENITORS IN WILMS TUMOR DEVELOPMENT, Le Huang
Dissertations and Theses (Open Access)

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THE ROLE OF AUTOPHAGY IN THE SENSITIVITY OF OSTEOSARCOMA CELLS TO GEMCITABINE TREATMENT, Janice M. Santiago-O'Farrill
Dissertations and Theses (Open Access)

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UNDERSTANDING THE ROLE OF SUMOYLATION IN REGULATING LKB1 FUNCTION, Joan W. Ritho
Dissertations and Theses (Open Access)

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DNA POLYMERASE θ (POLQ) AND THE CELLULAR DEFENSE AGAINST DNA DAMAGE, Matthew J. Yousefzadeh
Dissertations and Theses (Open Access)

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Regulation of Cell Adhesion by the FERM Proteins, PTPN14 and Merlin, Patty Dimarco Hewitt
Dissertations and Theses (Open Access)

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Investigating the roles of p63 and p73 isoforms to therapeutically treat p53-altered cancers, Avinashnarayan Venkatanarayan
Dissertations and Theses (Open Access)

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CANCER ASSOCIATED FIBROBLAST DERIVED ANGIOGENIC FACTOR MFAP5 IN OVARIAN CANCER PROGRESSION, SZE LEE CECILIA LEUNG
Dissertations and Theses (Open Access)

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MEASURING SINGLE CELL RESPONSES TO LAPATINIB IN A HETEROGENEOUS POPULATION, Preety Priya
Dissertations and Theses (Open Access)

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MICRORNA-200 REGULATES ECM-DEPENDENT β1-INTEGRIN/FAK SIGNALING AND CANCER CELL INVASION, Christin Ungewiss
Dissertations and Theses (Open Access)

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2014

MDM2-mediated degradation of SIRT6 phosphorylated by AKT1 promotes tumorigenesis and trastuzumab resistance in breast cancer, Umadevi Thirumurthi
Dissertations and Theses (Open Access)

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Sustained adrenergic signaling promotes cervical cancer progression, Nouara C. Sadaoui
Dissertations and Theses (Open Access)

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Novel Posttranslational Modification in LKB1 Activation and Function, Szu-Wei Lee
Dissertations and Theses (Open Access)

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p120-catenin regulates REST and CoREST, and modulates mouse embryonic stem cell differentiation, moonsup lee
Dissertations and Theses (Open Access)

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SOX2-DEPENDENT TRANSCRIPTIONAL CONTROL OF AIRWAY DIFFERENTIATION IN THE MOUSE LUNG, Belinda J. Hernandez
Dissertations and Theses (Open Access)

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LKB1 Deficient Non-small Cell Lung Cancer Cells are Vulnerable to Energy Stress Induced by ATP Depletion, Chao Yang
Dissertations and Theses (Open Access)

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EPIDERMAL GROWTH FACTOR RECEPTOR INDUCES FYN EXPRESSION VIA UP-REGULATION OF P47PHOX IN GLIOBLASTOMA MULTIFORME, Blake P. Johnson
Dissertations and Theses (Open Access)

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JAB1 NEGATIVELY REGULATES PTEN AND PROMOTES RESISTANCE TO TRASTUZUMAB IN HER2-POSITIVE BREAST CANCER, Thuy T. Vu
Dissertations and Theses (Open Access)

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ROLE OF PHOSPHORYLATION OF FOCAL ADHESION KINASE AT TYROSINE 861 IN PROSTATE CANCER METASTASIS, Tanushree Chatterji
Dissertations and Theses (Open Access)

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TARGETING COX-2 AND RANK IN AGGRESSIVE BREAST CANCERS: INFLAMMATORY BREAST CANCER AND TRIPLE-NEGATIVE BREAST CANCER, Monica Elizabeth Reyes
Dissertations and Theses (Open Access)

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Large-scale Identification of Chemically Induced Mutations in Drosophila melanogaster., Nele A Haelterman, Lichun Jiang, Yumei Li, Vafa Bayat, Hector Sandoval, Berrak Ugur, Kai Li Tan, Ke Zhang, Danqing Bei, Bo Xiong, Wu-Lin Charng, Theodore Busby, Adeel Jawaid, Gabriela David, Manish Jaiswal, Koen J T Venken, Shinya Yamamoto, Rui Chen, Hugo J Bellen
BCM Faculty Publications

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ROLES FOR B-Raf KINASE IN THE SPECIFIC REGULATION OF α4β1 INTEGRIN IN T CELLS, Wells S. Brown
Dissertations and Theses (Open Access)

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ENERGY STRESS CAUSES CHAPERONES TO ASSEMBLE INTO CYTOPLASMIC COMPLEXES, Kimberly J. Cope
Dissertations and Theses (Open Access)

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Mapping the Human Vasculature by In Vivo Phage Display, Julianna Bronk
Dissertations and Theses (Open Access)

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EGFR Modulates MicroRNA Maturation In Response To Hypoxia Through Phosphorylation Of Argonaute2, Jia Shen
Dissertations and Theses (Open Access)

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Strategies to sensitize bladder cancer cells to small molecule inhibitors targeting the PI3K pathway, Giovanni Nitti
Dissertations and Theses (Open Access)

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ANGIOMOTIN IS A NOVEL CADHERIN-11 INTERACTING PROTEIN THAT MEDIATES MIGRATION IN PROSTATE CANCER CELLS, Angelica Ortiz
Dissertations and Theses (Open Access)

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NUCLEAR TRANSLOCATION OF MET VIA INTERNET MECHANISM, MEI-KUANG CHEN
Dissertations and Theses (Open Access)

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BRIT1/MCPH1 MEDIATES THE DNA DAMAGE RESPONSE BY INDUCING P53 STABILITY AND PROMOTING ATR SIGNALING, Edward Wang
Dissertations and Theses (Open Access)

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CD56-SPECIFIC T CELLS: USING GENETICALLY ENGINEERED T CELLS TO REDIRECT SPECIFICITY TO A T CELL EXPRESSED ANTIGEN, Denise L. Crossland
Dissertations and Theses (Open Access)

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TYROSINE 370 PHOSPHORYLATION OF ATM POSITIVELY REGULATES DNA DAMAGE RESPONSE, Hong-Jen Lee
Dissertations and Theses (Open Access)

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Chemical mutagens, transposons, and transgenes to interrogate gene function in Drosophila melanogaster., Koen J T Venken, Hugo J Bellen
BCM Faculty Publications

CHARACTERIZATION OF FTSA-FTSN INTERACTION DURING ESCHERICHIA COLI CELL DIVISION, kimberly.busiek@gmail.com K. Busiek
Dissertations and Theses (Open Access)

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DIABETES AND OBESITY INDUCE TRANSCRIPTOMIC AND METABOLOMIC CHANGES ENHANCING PANCREATIC CANCER AGGRESSIVENESS, Guermarie Velázquez Torres
Dissertations and Theses (Open Access)

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The regulation of microRNA biogenesis by ribosome-interacting proteins, Brian Pickering
Dissertations and Theses (Open Access)

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CAR-MODIFIED T CELLS CAPABLE OF DISTINGUISHING NORMAL CELLS FROM MALIGNANT CELLS, Hillary G. Caruso
Dissertations and Theses (Open Access)

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ROLE OF TALIN1 PHOSPHORYLATION IN BETA1 INTEGRIN ACTIVATION AND PROSTATE CANCER METASTASIS, Jung-Kang Jin
Dissertations and Theses (Open Access)

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THE ASSOCIATION BETWEEN THE IL-1 PATHWAY, Isaac C. Wun
Dissertations and Theses (Open Access)

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MECHANISMS UNDERLYING DISTINCT EGFR VERSUS FGFR-3 AND -1 DEPENDENCY IN HUMAN BLADDER CANCER CELLS, Tiewei Cheng
Dissertations and Theses (Open Access)

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p53 MAINTAINS HEPATIC CELL IDENTITY DURING LIVER REGENERATION, Zeynep Hande Coban Akdemir
Dissertations and Theses (Open Access)

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Functional Analysis of Cytosolic Hsp70 Nucleotide Exchange Factor Networks in Yeast, Jennifer Lynn Abrams
Dissertations and Theses (Open Access)

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IMBALANCE BETWEEN NEUTROPHIL ELASTASE AND ELAFIN PROMOTES BREAST CANCER GROWTH AND PROGRESSION, Joseph Anthony Caruso
Dissertations and Theses (Open Access)

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MODULATED FUNCTIONS OF THE FANCONI ANEMIA CORE COMPLEX, Yaling Huang
Dissertations and Theses (Open Access)

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REGULATION OF MAMMARY GLAND DEVELOPMENT AND TUMORIGENESIS BY 14-3-3 ZETA, Sumaiyah Rehman
Dissertations and Theses (Open Access)

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ANTI-INSULIN RESISTANCE TREATMENTS SUPPRESS HER2+ BREAST CANCER GROWTH VIA ALTERING METABOLISM, PING-CHIEH CHOU
Dissertations and Theses (Open Access)

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NATURAL AND EXOGENOUS GENOME EDITING IN WISKOTT-ALDRICH SYNDROME PATIENT CELLS, Tamara J. Laskowski
Dissertations and Theses (Open Access)

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METADHERIN FUNCTIONS AS A LAMININ RECEPTOR THAT IS ESSENTIAL FOR METASTASIS AND IS ASSOCIATED WITH POOR SURVIVAL IN OSTEOSARCOMA, Limin Zhu
Dissertations and Theses (Open Access)

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2013

C-JUN N-TERMINAL KINASES REGULATE ADENOVIRUS-MEDIATED AUTOPHAGY AND ANTIGEN PRESENTATION, Sarah R. Klein
Dissertations and Theses (Open Access)

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INVESTIGATING APOPTOSIS PATHWAY IN CHRONIC LYMPHOCYTIC LEUKEMIA: STROMAL INFLUENCE AND THERAPEUTIC ACTIVATION, Viralkumar M. Patel
Dissertations and Theses (Open Access)

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EZH2 T416 Phosphorylation Enhances Breast Cancer Tumorigenesis, Adam M. LaBaff, Adam M. LaBaff
Dissertations and Theses (Open Access)

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DEVELOPMENTAL AND MOLECULAR FUNCTIONS OF PLAKOPHILIN-3, William A. Munoz
Dissertations and Theses (Open Access)

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A Genomic Approach to Identify The Notch Pathway as a Putative Tumor Suppressor in Endometrial Cancer, Rajshi Gandhi
Dissertations and Theses (Open Access)

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Characterization of Jak, STAT, and Src interactions in Head and Neck Squamous Cell Carcinoma, Reshma Jaseja, Reshma Jaseja
Dissertations and Theses (Open Access)

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The Role of K63-linked Ubiquitination Cycles in Akt Kinase Activation, Wei-Lei Yang
Dissertations and Theses (Open Access)

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T-CELL TREATMENTS FOR SOLID AND HEMATOLOGICAL TUMORS, Drew C. Deniger
Dissertations and Theses (Open Access)

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INVESTIGATING THE ROLES OF THE p63 ISOFORMS IN THE MICRORNA BIOGENESIS PATHWAY, Deepavali Chakravarti
Dissertations and Theses (Open Access)

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The Role of Type I Insulin-Like Growth Factor Receptor Signaling in Breast Cancer Brain Metastasis, Sandra M. Saldana
Dissertations and Theses (Open Access)

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Targeting Histone deacetylases (HDAC) for the treatment of soft tissue sarcoma, Gonzalo Lopez
Dissertations and Theses (Open Access)

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Acceleration of the PanIN Development in Mice Expressing Oncogenic K-Ras Due to a High Fat Diet, Bincy Philip
Dissertations and Theses (Open Access)

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The Role of Nucleolin in B-cell Lymphomas and Fas-Mediated Apoptotic Signaling, Jillian F. Wise
Dissertations and Theses (Open Access)

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Mechanisms Underlying the Heterogeneous Sensitivities of Cancer Cells to Proteasome Inhibitors, Matthew C. White
Dissertations and Theses (Open Access)

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THE p63 ISOFORM ∆Np63α INHIBITS EPITHELIAL – MESENCHYMAL TRANSITION BY PROMOTING THE EXPRESSION OF MIR-205 IN HUMAN BLADDER CANCER CELLS, Mai Tran
Dissertations and Theses (Open Access)

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OXIDATIVE STRESS BASED STRATEGIES FOR ENHANCING THE EFFICACY OF HISTONE DEACETYLASE INHIBITORS (HDACi), Nilsa Rivera-Del Valle
Dissertations and Theses (Open Access)

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CHARACTERIZATION OF DIFFERENTIATION AND PROGNOSTIC BIOMARKERS ON CD8+ TUMOR-INFILTRATING LYMPHOCYTES IN METASTATIC MELANOMA, Richard C. Wu
Dissertations and Theses (Open Access)

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Galectin-3 Enhances the Malignant Melanoma Phenotype by Regulating Autotaxin, Russell R. Braeuer
Dissertations and Theses (Open Access)

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Molecular Mechanisms of Vascular Disease in Patients with Rare Variants in MYH11, Callie Kwartler
Dissertations and Theses (Open Access)

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2012

FANCM AND FAAP24 MAINTAIN GENOMIC STABILITY THROUGH COOPERATIVE AND UNIQUE FUNCTIONS, Yucai Wang
Dissertations and Theses (Open Access)

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TET1: A UNIQUE DNA DEMETHYLASE FOR MAINTENANCE OF DNA METHYLATION PATTERN, CHUNLEI JIN
Dissertations and Theses (Open Access)

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ANTI-TUMOR EFFECTS OF THE NOTCH PATHWAY IN GASTROINTESTINAL STROMAL TUMORS, Amaury G. Dumont
Dissertations and Theses (Open Access)

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BIOCHEMICAL CHARACTERIZATION OF BINDING PARTNERS OF TWO HSP70 CO-CHAPERONES IN SACCHAROMYCES CEREVISIAE, Jacob Verghese
Dissertations and Theses (Open Access)

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Regulation of the heat shock response by thiol-reactive compounds in the yeast Saccharomyces cerevisiae, Yanyu Wang
Dissertations and Theses (Open Access)

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A STUDY ON THE FUNCTION OF 14-3-3SIGMA IN REGULATING CANCER ENERGY METABOLISM, Liem M. Phan, Liem M. Phan
Dissertations and Theses (Open Access)

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TRIM24-REGULATED ESTROGEN RESPONSE IS DEPENDENT ON SPECIFIC HISTONE MODIFICATIONS IN BREAST CANCER CELLS, Teresa T. Yiu
Dissertations and Theses (Open Access)

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GENETIC ANALYSIS OF THE HIPPO PATHWAY IN MOUSE LIVER, Li Lu
Dissertations and Theses (Open Access)

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Characterization of a Novel Role for the Tousled- like Kinase in Kinetochore Assembly and Function in Caenorhabditis elegans, Jessica M. De Orbeta
Dissertations and Theses (Open Access)

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TRANSCRIPTIONAL REGULATION OF PROFILIN IS REQUIRED FOR DROSOPHILA LARVAL WOUND CLOSURE, Amanda Brock
Dissertations and Theses (Open Access)

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ADHERENS JUNCTIONS AND THE ACTOMYOSIN NETWORK REGULATE ORGAN GROWTH BY MODULATING HIPPO PATHWAY ACTIVITY IN DROSOPHILA, Chih-Chao Yang
Dissertations and Theses (Open Access)

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Potential REST Targets in Neural Stem Cells and Glioblastoma-Derived Stem Cells, Frederick Scott Robinson
Dissertations and Theses (Open Access)

ROLE OF STAT3 IN KERATINOCYTE STEM CELLS DURING SKIN TUMORIGENESIS, Dharanija Rao
Dissertations and Theses (Open Access)

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Platelets and Anti-Angiogenic Resistance in Ovarian Carcinoma, Justin N. Bottsford-MIller
Dissertations and Theses (Open Access)

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REGULATION OF FOXC2 EXPRESSION AND FUNCTION DURING EPITHELIAL-MESENCHYMAL TRANSITION BY GSK-3β, Maryam Shariati
Dissertations and Theses (Open Access)

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IDENTIFICATION AND ANALYSIS OF A NOVEL ROLE FOR THE TOUSLED-LIKE KINASE IN REGULATING MITOTIC SPINDLE DYNAMICS, Jason R. Ford
Dissertations and Theses (Open Access)

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Syntaxin 6- and microtubule- mediated intracellular trafficking contributes to Golgi and nuclear translocation of EGFR, Yi Du
Dissertations and Theses (Open Access)

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Chronic stress promotes tumor growth through increased BDNF production and neo-innervation, Julie K. Allen
Dissertations and Theses (Open Access)

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14-3-3 ZETA OVEREXPRESSION SERVES AS A NOVEL MOLECULAR SWITCH TURNING TGF-BETA FROM TUMOR SUPPRESSOR TO TUMOR PROMOTER, Jia Xu
Dissertations and Theses (Open Access)

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Regulation of Protein Degradation in the Heart by AMP-Activated Protein Kinase, Kedryn K. Baskin, Kedryn K. Baskin
Dissertations and Theses (Open Access)

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Role of TRP Channels in Mediating the Calcium Signaling Response of Brain Endothelial Cells to Mechanical Stretch, Jonathan Berrout
Dissertations and Theses (Open Access)

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Regulation of Protein Degradation in the Heart by AMP-Activated Protein Kinase, Kedryn K. Baskin
Dissertations and Theses (Open Access)

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MicroRNA Regulation of Prostate Cancer Stem/Progenitor Cells and Prostate Cancer Development, Can Liu
Dissertations and Theses (Open Access)

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INDUCED-PLURIPOTENT STEM-DERIVED NEURONAL PROGENITOR CELLS AS A NOVEL TREATMENT FOR NEURODEGENERATIVE DISEASES, Dennisse A. Gonzalez-Romero
Dissertations and Theses (Open Access)

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LMW-E MEDIATES MAMMARY TUMORIGENESIS BY DEREGULATING ACINAR MORPHOGENESIS & GENERATING CANCER STEM CELLS, MyLinh T. Duong
Dissertations and Theses (Open Access)

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IDENTIFICATION AND CHARACTERIZATION OF DISTINCT POPULATIONS OF CLONOGENIC BONE MARROW STROMAL CELLS CAPABLE OF TRANSFERRING THE HEMATOPOIETIC MICROENVIRONMENT IN VIVO AND SUPPORTING LT-HSCs IN VITRO, Colby Suire
Dissertations and Theses (Open Access)

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Elucidating the IGFBP2 signaling pathway in glioma development and progression, Kristen M. Holmes
Dissertations and Theses (Open Access)

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Increased geranylgeranylated K-Ras contributes to antineoplastic effects of farnesyltransferase inhibitors., Mandy A. Hall
Dissertations and Theses (Open Access)

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2011

REGULATION OF HGF EXPRESSION BY ΔEGFR-MEDIATED C-MET ACTIVATION IN GLIOBLASTOMA CELLS, Jeannine Garnett
Dissertations and Theses (Open Access)

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THE ROLE OF E2F1 IN THE RESPONSE TO DNA DOUBLE STRAND BREAKS, Jie Chen
Dissertations and Theses (Open Access)

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DEFINITION OF THE LANDSCAPE OF CHROMATIN STRUCTURE AT THE FRATAXIN GENE IN FRIEDREICH’S ATAXIA, Eunah Kim
Dissertations and Theses (Open Access)

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IDENTIFICATION OF FACTORS INVOLVED IN DNA METHYLATION OF CPG-ISLAND-PROMOTERS, Yan Zhang
Dissertations and Theses (Open Access)

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MODELLING β2AR REGULATION, Sharat J. Vayttaden
Dissertations and Theses (Open Access)

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THE ROLE OF RECEPTOR TYROSINE KINASE AXL IN PANCREATIC DUCTAL ADENOCARCINOMA AND ITS REGULATION BY HEMATOPOIETIC PROGENITOR KINASE 1, Xianzhou Song
Dissertations and Theses (Open Access)

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THE ROLE OF TAK1 IN PANCREATIC CANCER DEVELOPMENT, qianghua xia
Dissertations and Theses (Open Access)

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FUNCTION OF ZNF668 IN CANCER DEVELOPMENT, Ruozhen Hu
Dissertations and Theses (Open Access)

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Mechanisms of Adenovirus-Mediated Autophagy, Erin White
Dissertations and Theses (Open Access)

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STAT3 CONTROLS THE NEUTROPHIL MIGRATORY RESPONSE TO CXCR2 AND ITS LIGAND MIP-2 (CXCL2), Hoainam Nguyen-Jackson
Dissertations and Theses (Open Access)

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ROLE OF PROSTAGLANDIN E2 IN THE REGULATION OF PANCREATIC STELLATE CELLS HYPER ACTIVITY ASSOCIATED WITH PANCREATIC CANCER, Chantale Charo
Dissertations and Theses (Open Access)

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The Role of the Androgen Receptor Cofactor p44/WDR77 in Astrocyte Activation, Bryce H. Vincent
Dissertations and Theses (Open Access)

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Enforced expression of Tbx1 in fetal thymic epithelial cells antagonizes thymus organogenesis, Kim T. Cardenas
Dissertations and Theses (Open Access)

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