Duncan NRI Faculty and Staff Publications
The Jan and Dan Duncan Neurological Institute is home to 37 Principal Investigators, more than 400+ scientists and 10 Core labs.
Dan and Duncan Neurological Institute also house the Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories which are focused on epilepsy research and Baylor College's of Medicine's Center for Drug Discovery which is aimed at quick identification and advancement of small molecules to clinical trials.
Since inception, more than 1700 scientific studies have been published, and more than 85 disease-causing genetic mutations have been discovered or co-discovered by our scientists. There are currently 6 active clinical trials and studies.
Submissions from 2025
Acute MeCP2 Loss in Adult Mice Reveals Transcriptional and Chromatin Changes That Precede Neurological Dysfunction and Inform Pathogenesis, Sameer S Bajikar, Jian Zhou, Ryan O'Hara, et al.
IGF-1 Impacts Neocortical Interneuron Connectivity in Epileptic Spasm Generation and Resolution, Carlos J Ballester-Rosado, John T Le, Trang T Lam, et al.
Comparative Analysis of AAV Serotypes for Transduction of Olfactory Sensory Neurons, Benjamin D W Belfort, Johnathan D Jia, Alexandra R Garza, et al.
Sex-Specific Astrocyte Regulation of Spinal Motor Circuits by Nkx6.1, Navish A Bosquez Huerta, Zhung-Fu Lee, Eun-Ah Christine Song, et al.
Volumetric Changes in Cerebellar Transverse Zones: Age and Sex Effects in Health and Neurological Disorders, Farshid Ghiyamihoor, Payam Paymani, Jarrad Perron, et al.
Diverse Ancestral Representation Improves Genetic Intolerance Metrics, Alexander L Han, Chloe F Sands, Dorota Matelska, et al.
Breaking the Synaptic Vesicle Cycle: Mechanistic Insights into Presynaptic Dysfunctions in Epilepsy, Kevin Jiang, Lu-Tang Yang, and Mingshan Xue
Molecular Logic for Cellular Specializations That Initiate the Auditory Parallel Processing Pathways, Junzhan Jing, Ming Hu, Tenzin Ngodup, et al.
Protocol for Unlocking Alternative Polyadenylation Insights From Bulk RNA-Seq Data With PolyAMiner-Bulk, Venkata Jonnakuti, Sriya Jonnakuti, and Hari Krishna Yalamanchili
The Small GTPase Rap1 in POMC Neurons Regulates Leptin Actions and Glucose Metabolism, Kentaro Kaneko, Weisheng Lu, Yong Xu, et al.
Alpha-Synuclein Phosphomimetic Y39E and S129D Knock-In Mice Show Cytosolic Alpha-Synuclein Localization without Developing Neurodegeneration or Motor Deficits, YoungDoo Kim, Bhupesh Vaidya, Joseph McInnes, et al.
Multi-Omics Delineate Growth Factor Network Underlying Exercise Effects in an Alzheimer’s Mouse Model, Xin Li, Chaozhong Liu, Wenbo Li, et al.
Longitudinal Multi-Omics in Alpha-Synuclein Drosophila Model Discriminates Disease- From Age-Associated Pathologies in Parkinson’s Disease, Justin Moore, Timothy Wu, Justin Dhindsa, et al.
Comprehensive Assessment Reveals Numerous Clinical and Neurophysiological Differences Between MECP2-Allelic Disorders, Davut Pehlivan, Chengjun Huang, Holly K Harris, et al.
Investigation of Dynamic Regulation of TFEB Nuclear Shuttling by Microfluidics and Quantitative Modelling, Iacopo Ruolo, Sara Napolitano, Lorena Postiglione, et al.
Submissions from 2024
The DDHD2-STXBP1 Interaction Mediates Long-Term Memory via Generation of Saturated Free Fatty Acids, Isaac O Akefe, Saber H Saber, Benjamin Matthews, et al.
CPSF3 Inhibition Blocks Pancreatic Cancer Cell Proliferation Through Disruption of Core Histone mRNA Processing, Abdulrahman A Alahmari, Aditi H Chaubey, Venkata S Jonnakuti, et al.
TFEB Drives mTORC1 Hyperactivation and Kidney Disease in Tuberous Sclerosis Complex, Nicola Alesi, Damir Khabibullin, Dean M Rosenthal, et al.
Individualized Functional Magnetic Resonance Imaging Neuromodulation Enhances Visuospatial Perception: A Proof-of-Concept Study, Anthony Allam, Vincent Allam, Sandy Reddy, et al.
Individualized Functional Magnetic Resonance Imaging Neuromodulation Enhances Visuospatial Perception: A Proof-of-Concept Study, Anthony Allam, Vincent Allam, Sandy Reddy, et al.
MECP2-Related Disorders While Gene-Based Therapies Are on the Horizon, Katherine Allison, Mirjana Maletic-Savatic, and Davut Pehlivan
Oligodendroglial Fatty Acid Metabolism as a Central Nervous System Energy Reserve, Ebrahim Asadollahi, Andrea Trevisiol, Aiman S Saab, et al.
Modeling Antisense Oligonucleotide Therapy in MECP2 Duplication Syndrome Human iPSC-Derived Neurons Reveals Gene Expression Programs Responsive to MeCP2 Levels, Sameer S Bajikar, Yehezkel Sztainberg, Alexander J Trostle, et al.
Signaling Mechanisms Underlying Activity-Dependent Integration of Adult-Born Neurons in the Mouse Olfactory Bulb, Suyang Bao, Juan M Romero, Benjamin D W Belfort, et al.
Single-Cell Multi-Omic Analysis of the Vestibular Schwannoma Ecosystem Uncovers a Nerve Injury-Like State, Thomas F Barrett, Bhuvic Patel, Saad M Khan, et al.