First published in Rome in 1556, Juan Valverde de Amusco’s Anatomia del corpo humano became one of the most influential anatomical books of the Renaissance. Valverde drew heavily on the anatomical discoveries of Andreas Vesalius but presented them through a new series of finely engraved illustrations that clarified and expanded Vesalian imagery. One of the most famous images in the book depicts a flayed figure holding its own skin, a dramatic visualization of the muscular system that reflects the close relationship between Renaissance art and anatomical study. Works such as this helped spread the new visual language of anatomy across Europe.