The revised Society for Cardiovascular Angiography and Interventions classifications reflect graduation of severity within each stage and pathway by which patients progress or recover. However, they are limited regarding the following: their predictive role to guide therapy; escalation of therapy or referral; variability in diagnostic criteria and interpretation; presence of other disease modifiers and confounders; variability of etiology and reversibility of cause; response to therapy and trajectory to be taken into risk stratification; magnitude and phenotypes of end-organ damage. Thus, we need a modified risk score to predict the necessity to escalate therapy and consider advanced therapies, such as mechanical circulatory support. Future research on validation studies and reclassification analyses is needed.
"SCAI SHOCK Stage Classification: What is Missing from the Latest Update?,"
Journal of Shock and Hemodynamics: Vol. 1(1)
Available at: https://digitalcommons.library.tmc.edu/josh/vol1/iss1/12