Through the years, epinephrine has been the drug of choice for patients with cardiogenic shock. However, epinephrine was clinically inferior to norepinephrine in comparison studies because of the negative patient outcomes, which were statistically significant. These effects include type B lactic acidosis, tachycardia, increased myocardial oxygen demand, and arrhythmias.
"Why is Epinephrine Not the Drug of Choice in Cardiogenic Shock?,"
Journal of Shock and Hemodynamics: Vol. 1(2)
Available at: https://digitalcommons.library.tmc.edu/josh/vol1/iss2/10