The efficacy of mechanical circulatory support in acute myocardial infarction is dependent upon the size of the infarct. If applied early, mechanical support to reduce reperfusion injury appears to be effective in reducing infarct size in animal studies. The optimal timing of reperfusion is uncertain and requires further investigation. Efficient unloading appears to be essential in increasing the efficacy of the type of mechanical support and may favor one over another.
"Reperfusion Injury in Acute Myocardial Infarction Shock- Role of Mechanical Circulatory Support Devices,"
Journal of Shock and Hemodynamics: Vol. 1(2)
Available at: https://digitalcommons.library.tmc.edu/josh/vol1/iss2/8