Center for Medical Ethics and Health Policy Staff Publications
Publication Date
4-1-2024
Journal
Journal of Allergy and Clinical Immunology
DOI
10.1016/j.jaci.2024.01.014
PMID
38295882
PMCID
PMC10999353
PubMedCentral® Posted Date
4-1-2025
PubMedCentral® Full Text Version
Author MSS
Published Open-Access
yes
Keywords
United States, Humans, National Institute of Allergy and Infectious Diseases (U.S.), Hypersensitivity, Asthma, Genomics, Proteomics, Metabolomics, omics, genomics, epigenomics, transcriptomics, microbiome, proteomics, metabolomics, lipidomics, integrative, systems biology, causal inference, asthma, allergy, allergic diseases
Abstract
Studies of asthma and allergy are generating increasing volumes of omics data for analysis and interpretation. The National Institute of Allergy and Infectious Diseases (NIAID) assembled a workshop comprising investigators studying asthma and allergic diseases using omics approaches, omics investigators from outside the field, and NIAID medical and scientific officers to discuss the following areas in asthma and allergy research: genomics, epigenomics, transcriptomics, microbiomics, metabolomics, proteomics, lipidomics, integrative omics, systems biology, and causal inference. Current states of the art, present challenges, novel and emerging strategies, and priorities for progress were presented and discussed for each area. This workshop report summarizes the major points and conclusions from this NIAID workshop. As a group, the investigators underscored the imperatives for rigorous analytic frameworks, integration of different omics data types, cross-disciplinary interaction, strategies for overcoming current limitations, and the overarching goal to improve scientific understanding and care of asthma and allergic diseases.
Included in
Allergy and Immunology Commons, Bioethics and Medical Ethics Commons, Biological Phenomena, Cell Phenomena, and Immunity Commons, Health Policy Commons, Medical Immunology Commons