Children’s Nutrition Research Center Staff Publications
Publication Date
11-25-2022
Journal
Science
DOI
10.1126/science.abm8668
PMID
36423296
PMCID
PMC9764345
PubMedCentral® Posted Date
12-20-2022
PubMedCentral® Full Text Version
Author MSS
Published Open-Access
yes
Keywords
Female, Humans, Pregnancy, Exercise, Humidity, Life Style, Social Class, Water, Infant, Newborn, Infant, Child, Preschool, Child, Adolescent, Young Adult, Adult, Middle Aged, Aged, Aged, 80 and over, Drinking
Abstract
Water is essential for survival, but one in three individuals worldwide (2.2 billion people) lack access to safe drinking water. Water intake requirements largely reflect water turnover (WT), the water used by the body each day. We investigated the determinants of human WT in 5,604 people from the ages of 8 days to 96 years from 26 countries using isotope tracking (2H) methods. Age, body size, and composition were significantly associated with WT as were physical activity, athletic status, pregnancy, socioeconomic status, and environmental characteristics (latitude, altitude, air temperature, and humidity). People in countries with low human development index (HDI) had higher water turnover than people who lived in countries with high HDI. Based on this extensive dataset we provide equations to predict human water requirements in relation to anthropometric, economic, and environmental factors.
Included in
Biochemical Phenomena, Metabolism, and Nutrition Commons, Dietetics and Clinical Nutrition Commons, Endocrinology, Diabetes, and Metabolism Commons, Environmental Public Health Commons, Nutrition Commons