Student and Faculty Publications
Publication Date
11-13-2023
Journal
Cancer Cell
Abstract
Increasing evidence suggests that tumors harbor diverse microbiomes, adding complexity to the tumor microenvironment. In this issue of Cancer Cell, Liu et al. highlight the role of the intratumor mycobiome, specifically Aspergillus sydowii, in promoting lung adenocarcinoma progression. A. sydowii enhances the recruitment and activation of myeloid-derived suppressor cells via IL-1β signaling driven by the β-glucan-mediated Dectin-1/CARD9 pathway.
Keywords
Humans, Mycobiome, Signal Transduction, beta-Glucans, Adenocarcinoma of Lung, Bacteria, Tumor Microenvironment
Included in
Bioinformatics Commons, Biomedical Informatics Commons, Diseases Commons, Medical Sciences Commons, Oncology Commons
Comments
PMID: 37774700