Home-Based Spirometry Telemonitoring After Allogeneic Hematopoietic Cell Transplantation: Mixed Methods Evaluation of Acceptability and Usability

Authors

Ajay Sheshadri
Sukh Makhnoon
Amin M Alousi
Lara Bashoura
Rene Andrade
Christopher J Miller
Karen R Stolar
Muhammad Hasan Arain
Laila Noor
Amulya Balagani
Akash Jain
David Blanco
Abel Ortiz
Michael S Taylor
Alex Stenzler
Rohtesh Mehta
Uday R Popat
Chitra Hosing
David E Ost
Richard E Champlin
Burton F Dickey
Susan K Peterson

Publication Date

2-7-2022

Journal

JMIR Formative Research

Abstract

Background: Home-based spirometry (HS) allows for the early detection of lung complications in recipients of an allogeneic hematopoietic cell transplant (AHCT). Although the usability and acceptability of HS are critical for adherence, patient-reported outcomes of HS use remain poorly understood in this setting.

Objective: The aim of this study is to design a longitudinal, mixed methods study to understand the usability and acceptability of HS among recipients of AHCT.

Methods: Study participants performed HS using a Bluetooth-capable spirometer that transmitted spirometry data to the study team in real time. In addition, participants completed usability questionnaires and in-depth interviews and reported their experiences with HS. Analysis of interview data was guided by the constructs of performance expectancy, effort expectancy, and social influence from the Unified Theory of Acceptance and Use of Technology model.

Results: Recipients of AHCT found HS to be highly acceptable despite modest technological barriers. On average, participants believed that the HS was helpful in managing symptoms related to AHCT (scores ranging from 2.22 to 2.68 on a scale of 0-4) and for early detection of health-related problems (score range: 2.88-3.12). Participants viewed HS favorably and were generally supportive of continued use. No significant barriers to implementation were identified from the patient's perspective. Age and gender were not associated with the patient perception of HS.

Conclusions: Study participants found HS acceptable and easy to use. Some modifiable technical barriers to performing HS were identified; however, wider implementation of pulmonary screening is feasible from the patient's perspective.

Keywords

allogeneic hematopoietic cell transplantation, home-based spirometry, acceptability, usability, mixed methods evaluation, patient perspectives, spirometry, feasibility, mHealth, home-based, remote care, respirology, pulmonary medicine, mobile phone

DOI

10.2196/29393

PMID

35129455

PMCID

PMC8861865

PubMedCentral® Posted Date

2-7-2022

PubMedCentral® Full Text Version

Post-print

Published Open-Access

yes