Faculty, Staff and Student Publications
Publication Date
1-1-2022
Journal
American Journal of Clinical Dermatology
Abstract
Granuloma annulare (GA) is an inflammatory granulomatous skin disease that can be localized (localized GA) or disseminated (generalized GA), with patch, perforating, and subcutaneous subtypes being less common variants of this benign condition. Recently, new research has emerged that further elucidates GA epidemiology and etiopathogenesis; importantly, new therapeutic options for GA have also been described, although there remains a paucity of randomized controlled studies. In this review, we summarize recent updates on GA epidemiology and etiopathogenesis and offer an updated review of the therapeutic options for GA currently reported in the literature. We hope that the current review galvanizes randomized controlled studies that will in turn help lead to the recommendation of evidence-based treatments for GA.
Keywords
Anti-Infective Agents, Antimalarials, Biological Therapy, Comorbidity, Dermatologic Agents, Diabetes Complications, Diagnosis, Differential, Glucocorticoids, Granuloma Annulare, Humans, Iatrogenic Disease, Infections, Methotrexate, Neoplasms, Pentoxifylline, Phosphodiesterase 4 Inhibitors, Phototherapy, Piperidines, Pyrimidines, Thalidomide
DOI
10.1007/s40257-021-00636-1
PMID
4495491
PMCID
PMC8423598
PubMedCentral® Posted Date
9-8-2021
PubMedCentral® Full Text Version
Post-print
Published Open-Access
yes
Included in
Bioinformatics Commons, Biomedical Informatics Commons, Dermatology Commons, Genetic Phenomena Commons, Medical Genetics Commons, Oncology Commons, Skin and Connective Tissue Diseases Commons