Faculty, Staff and Student Publications
Publication Date
1-1-2023
Journal
CA: A Cancer Journal for Clinicians
Abstract
Sinonasal malignancies make up <5% of all head and neck neoplasms, with an incidence of 0.5-1.0 per 100,000. The outcome of these rare malignancies has been poor, whereas significant progress has been made in the management of other cancers. The objective of the current review was to describe the incidence, causes, presentation, diagnosis, treatment, and recent developments of malignancies of the sinonasal tract. The diagnoses covered in this review included sinonasal undifferentiated carcinoma, sinonasal adenocarcinoma, sinonasal squamous cell carcinoma, and esthesioneuroblastoma, which are exclusive to the sinonasal tract. In addition, the authors covered malignances that are likely to be encountered in the sinonasal tract-primary mucosal melanoma, NUT (nuclear protein of the testis) carcinoma, and extranodal natural killer cell/T-cell lymphoma. For the purpose of keeping this review as concise and focused as possible, sarcomas and malignancies that can be classified as salivary gland neoplasms were excluded.
Keywords
Humans, Carcinoma, Maxillary Sinus Neoplasms, Melanoma, Nasal Cavity, Nose Neoplasms, Paranasal Sinuses, rare diseases, head and neck neoplasms, paranasal sinus neoplasms, sinonasal carcinoma
DOI
10.3322/caac.21752
PMID
35916666
PMCID
PMC9840681
PubMedCentral® Posted Date
1-1-2024
PubMedCentral® Full Text Version
Post-print
Published Open-Access
yes
Included in
Bioinformatics Commons, Biomedical Informatics Commons, Genetic Phenomena Commons, Medical Genetics Commons, Neoplasms Commons, Oncology Commons