Faculty, Staff and Student Publications
Publication Date
4-4-2024
Journal
Cancer Discovery
Abstract
Research on precancers, as defined as at-risk tissues and early lesions, is of high significance given the effectiveness of early intervention. We discuss the need for risk stratification to prevent overtreatment, an emphasis on the role of genetic and epigenetic aging when considering risk, and the importance of integrating macroenvironmental risk factors with molecules and cells in lesions and at-risk normal tissues for developing effective intervention and health policy strategies.
Keywords
Humans, Precancerous Conditions, Risk Factors
DOI
10.1158/2159-8290.CD-23-1550
PMID
38571435
PMCID
PMC11170686
PubMedCentral® Posted Date
3-4-2025
PubMedCentral® Full Text Version
Author MSS
Published Open-Access
yes
Included in
Bioinformatics Commons, Biomedical Informatics Commons, Genetic Phenomena Commons, Medical Genetics Commons, Oncology Commons