Incidental Detection of a Rare Pediatric High-Grade Fibrosarcoma in a Post-traumatic Setting: The Conundrum of Intra-Abdominal Hematoma versus Neoplasia

Authors

Kamand Khalaj
Nikoo Fattahi
Allen C Omo-Ogboi
Jaiyeola O Thomas-Ogunniyi
Olanrewaju A Ogunleye
Ashish Khanal
Larry A Kramer

Publication Date

1-1-2023

Journal

Case Reports in Radiology

Abstract

Infantile fibrosarcoma (IF) is a rare malignant fibroblastic tumor that affects infants and young children, occurring most commonly in the extremities. Here, we present a 14-year-old patient with an abdominal mass incidentally detected after a blunt injury to the abdomen. The initial trauma protocol CT revealed a high attenuation mesenteric lesion in the left central abdomen suggestive of mesenteric hematoma. However, the possibility of a solid neoplastic mass lesion could not be excluded. Further evaluation with dynamic contrast-enhanced serial MRI showed a progressive enhancing mass and excluded a hyperacute hematoma with active bleeding. The mass was resected, and histopathological examination and molecular analysis of tumor cells were consistent with a high-grade fibrosarcoma with KMT2D : BCOR fusion.

DOI

10.1155/2023/3178778

PMID

38089103

PMCID

PMC10715857

PubMedCentral® Posted Date

December 2023

PubMedCentral® Full Text Version

Post-print

Published Open-Access

yes