Publication Date



Cellular Reprogramming


By dissecting and comparing the transcriptional trajectories and epigenomic traits of reprogramming and transforming cells at the single-cell resolution, Huyghe et al discovered Bcl11b and Atoh8, two key transcription factors controlling cell plasticity during pluripotent reprogramming and oncogenic transformation.


Humans, Cell Plasticity, Transcription Factors, Cell Transformation, Neoplastic, Tumor Suppressor Proteins, Cellular Reprogramming, Repressor Proteins



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