
Faculty, Staff and Student Publications
Publication Date
1-1-2023
Journal
Frontiers in Bioengineering and Biotechnology
Abstract
With the increasing demand for biomarker detection in wearable electronic devices, flexible biosensors have garnered significant attention. Additionally, graphene field-effect transistors (GFETs) have emerged as key components for constructing biosensors, owing to their high sensitivity, multifunctionality, rapid response, and low cost. Leveraging the advantages of flexible substrates, such as biocompatibility, adaptability to complex environments, and fabrication flexibility, flexible GFET sensors exhibit promising prospects in detecting various biomarkers. This review provides a concise summary of design strategies for flexible GFET biosensors, including non-encapsulated gate without dielectric layer coverage and external gate designs. Furthermore, notable advancements in sensing applications of biomolecules, such as proteins, glucose, and ions, are highlighted. Finally, we discuss the future challenges and prospects in this field, aiming to inspire researchers to address these issues in their further investigations.
Keywords
flexible, graphene field-effect transistor, biomolecule, biosensor, biomarker
DOI
10.3389/fbioe.2023.1218024
PMID
37485314
PMCID
PMC10361656
PubMedCentral® Posted Date
July 2023
PubMedCentral® Full Text Version
Post-print
Published Open-Access
yes