An update on pathobiologic roles of anti-glycan antibodies in Guillain-Barré syndrome
Publication Date
1-1-2010
Journal
F1000 Biol Rep. 2010; 2: 21.
Abstract
Anti-glycan antibodies directed against gangliosides are now considered the major immune effectors that induce damage to intact nerve fibers in some variants of the monophasic neuropathic disorders that comprise Guillain-Barré syndrome. Recent experimental studies elucidating the complexity of anti-glycan antibody-mediated pathobiologic effects on intact and injured nerves undergoing repair are discussed.