Faculty, Staff and Student Publications
Publication Date
12-1-2022
Journal
Eye
Abstract
Purpose: To describe clinical characteristics and visual outcomes of non-traumatic open globe injuries.
Setting: A level 1 trauma centre in a large urban medical centre.
Design: Retrospective study.
Methods: Charts of non-traumatic open globe patients admitted to MHH-TMC from 1/2010 to 3/2015 were reviewed for demographics, cause, clinical characteristics, visual acuity (VA) and enucleation.
Results: Thirty eyes were included: 15 (50%) were males with a mean age of 47 (±28) years. All presented with zone 1 injury. Twenty-five (83%) had a perforated corneal ulcer. Presenting VA was count fingers (n = 3, 10%) to NLP (n = 6, 20%). Twenty-four (80%) involved infection, 5 (17%) congenital, 3 (10%) chemical burn and 2 (7%) neurotrophic. Conjunctival injection (n = 22, 77%), corneal opacification (n = 20, 71%) and relative afferent pupillary defect (n = 9, 44%) were common. After treatment, 23 (88%) were worse than 6/60 (20/200), 9 (35%) were NLP and 8 (27%) required enucleation.
Conclusions: Often non-traumatic open globe injuries are zone 1 and due to perforated infectious ulcers. Compared to previously reported traumatic injuries, these have higher rates of enucleation (27% vs 8%) and poorer final VA (88% vs 68% worse than 6/60 20/200).
Keywords
Humans, Male, Middle Aged, Female, Eye Injuries, Penetrating, Retrospective Studies, Visual Acuity, Vision Disorders, Prognosis
DOI
10.1038/s41433-021-01869-4
PMID
34857923
PMCID
PMC9674630
PubMedCentral® Posted Date
12-2-2021
PubMedCentral® Full Text Version
Post-print
Published Open-Access
yes