Faculty, Staff and Student Publications
Publication Date
5-1-2024
Journal
American Journal of Physical Medicine & Rehabilitation
Abstract
Objective: This quasi-experimental study examined the effect of repetitive finger stimulation on brain activation in eight stroke and seven control subjects, measured by quantitative electroencephalogram.
Methods: We applied 5 mins of 2-Hz repetitive bilateral index finger transcutaneous electrical nerve stimulation and compared differences pre- and post-transcutaneous electrical nerve stimulation using quantitative electroencephalogram metrics delta/alpha ratio and delta-theta/alpha-beta ratio.
Results: Between-group differences before and after stimulation were significantly different in the delta/alpha ratio ( z = -2.88, P = 0.0040) and the delta-theta/alpha-beta ratio variables ( z = -3.90 with P < 0.0001). Significant decrease in the delta/alpha ratio and delta-theta/alpha-beta ratio variables after the transcutaneous electrical nerve stimulation was detected only in the stroke group (delta/alpha ratio diff = 3.87, P = 0.0211) (delta-theta/alpha-beta ratio diff = 1.19, P = 0.0074).
Conclusions: The decrease in quantitative electroencephalogram metrics in the stroke group may indicate improved brain activity after transcutaneous electrical nerve stimulation. This finding may pave the way for a future novel therapy based on transcutaneous electrical nerve stimulation and quantitative electroencephalogram measures to improve brain recovery after stroke.
Keywords
Humans, Stroke, Transcutaneous Electric Nerve Stimulation, Fingers, Brain, Survivors
DOI
10.1097/PHM.0000000000002393
PMID
38261754
PMCID
PMC11031333
PubMedCentral® Posted Date
5-1-2025
PubMedCentral® Full Text Version
Author MSS
Published Open-Access
yes
Comments
This article has been corrected. See Am J Phys Med Rehabil. 2024 Nov 1;103(11):1062.