Faculty, Staff and Student Publications
Publication Date
10-1-2024
Journal
iMeta
Abstract
T cell is an indispensable component of the immune system and its multifaceted functions are shaped by the distinct T cell types and their various states. Although multiple computational models exist for predicting the abundance of diverse T cell types, tools for assessing their states to characterize their degree of resting, activation, and suppression are lacking. To address this gap, a robust and nuanced scoring tool called T cell state identifier (TCellSI) leveraging Mann-Whitney
Keywords
T cell states, TCellSI, TCSS, immune profiling, immunotherapy
DOI
10.1002/imt2.231
PMID
39429885
PMCID
PMC11487559
PubMedCentral® Posted Date
8-26-2024
PubMedCentral® Full Text Version
Post-print
Published Open-Access
yes
Included in
Bioinformatics Commons, Biomedical Informatics Commons, Immunotherapy Commons, Medical Immunology Commons