Integrated Molecular and Affiliation Network Analysis: Core-Periphery Social Clustering Is Associated With HIV Transmission Patterns

Authors

Kayo Fujimoto
Dimitrios Paraskevis
Jacky C Kuo
Camden J Hallmark
Jing Zhao
Andre Hochi
Lisa M Kuhns
Lu-Yu Hwang
Angelos Hatzakis
John A Schneider

Publication Date

1-1-2022

Journal

Social Networks

Abstract

This study investigates the two-mode core-periphery structures of venue affiliation networks of younger Black men who have sex with men (YBMSM). We examined the association between these structures and HIV phylogenetic clusters, defined as members who share highly similar HIV strains that are regarded as a proxy for sexual affiliation networks. Using data from 114 YBMSM who are living with HIV in two large U.S. cities, we found that HIV phylogenetic clustering patterns were associated with social clustering patterns whose members share affiliation with core venues that overlap with those of YBMSM. Distinct HIV transmission patterns were found in each city, a finding that can help to inform tailored venue-based and network intervention strategies.

Keywords

social determinants of health, racial disparity, HIV transmission networks, phylogenetics, venue affiliation network, core-periphery structure, young black men who have sex with men, sexual networks

DOI

10.1016/j.socnet.2021.05.003

PMID

34262236

PMCID

PMC8274587

PubMedCentral® Posted Date

1-1-2023

PubMedCentral® Full Text Version

Author MSS

Published Open-Access

yes